3IB8
Crystal structure of full length Rv0805 in complex with 5'-AMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004112 | molecular_function | cyclic-nucleotide phosphodiesterase activity |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0004115 | molecular_function | 3',5'-cyclic-AMP phosphodiesterase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008199 | molecular_function | ferric iron binding |
| A | 0008663 | molecular_function | 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0030313 | cellular_component | cell envelope |
| A | 0042301 | molecular_function | phosphate ion binding |
| A | 0042545 | biological_process | cell wall modification |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047555 | molecular_function | 3',5'-cyclic-GMP phosphodiesterase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE A 444 |
| Chain | Residue |
| A | ASP21 |
| A | HIS23 |
| A | ASP63 |
| A | HIS209 |
| A | MN555 |
| A | HOH565 |
| A | AMP666 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 555 |
| Chain | Residue |
| A | HIS169 |
| A | HIS207 |
| A | FE444 |
| A | HOH565 |
| A | AMP666 |
| A | ASP63 |
| A | ASN97 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE AMP A 666 |
| Chain | Residue |
| A | HIS23 |
| A | ASP63 |
| A | ASN97 |
| A | HIS98 |
| A | ALA157 |
| A | MET179 |
| A | ALA180 |
| A | THR182 |
| A | HIS207 |
| A | LEU208 |
| A | HIS209 |
| A | HOH359 |
| A | FE444 |
| A | HOH474 |
| A | HOH485 |
| A | HOH492 |
| A | HOH495 |
| A | HOH499 |
| A | HOH500 |
| A | HOH549 |
| A | MN555 |
| A | HOH565 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE BTB A 777 |
| Chain | Residue |
| A | ASP66 |
| A | LYS67 |
| A | ASN97 |
| A | HIS98 |
| A | ASP99 |
| A | VAL121 |
| A | PRO137 |
| A | GLY138 |
| A | HIS140 |
| A | GLU155 |
| A | HOH387 |
| A | HOH393 |
| A | HOH512 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 778 |
| Chain | Residue |
| A | VAL92 |
| A | TRP93 |
| A | ARG120 |
| A | CYS122 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 779 |
| Chain | Residue |
| A | ASP119 |
| A | SER147 |
| A | TRP151 |
| A | HOH383 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MPD A 780 |
| Chain | Residue |
| A | ARG77 |
| A | GLU81 |
| A | LEU109 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1000 |
| Chain | Residue |
| A | ALA160 |
| A | HOH481 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17059828","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19801656","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19801656","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IB8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
