Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE 2NC A 204 |
| Chain | Residue |
| A | ARG8 |
| A | ILE50 |
| A | PHE53 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | LEU127 |
| A | ASP129 |
| A | GLY131 |
| A | ALA132 |
| A | ASP133 |
| A | ASP25 |
| A | ASP134 |
| A | ILE151 |
| A | GLY152 |
| A | GLY153 |
| A | ILE154 |
| A | PRO185 |
| A | ILE188 |
| A | HOH208 |
| A | HOH209 |
| A | HOH214 |
| A | GLY27 |
| A | HOH219 |
| A | HOH289 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | LYS55 |
| A | VAL56 |
| A | ARG57 |
| A | GLU65 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
| A | ALA126-ILE137 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Region: {"description":"Dimerization of protease","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For protease activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
3IAW
