3I9L
Crystal structure of ADP ribosyl cyclase complexed with N1-cIDPR
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003953 | molecular_function | NAD+ nucleosidase activity |
A | 0005886 | cellular_component | plasma membrane |
A | 0007338 | biological_process | single fertilization |
A | 0016020 | cellular_component | membrane |
A | 0016740 | molecular_function | transferase activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016849 | molecular_function | phosphorus-oxygen lyase activity |
A | 0030890 | biological_process | positive regulation of B cell proliferation |
A | 0031410 | cellular_component | cytoplasmic vesicle |
A | 0061809 | molecular_function | NAD+ nucleotidase, cyclic ADP-ribose generating |
B | 0003953 | molecular_function | NAD+ nucleosidase activity |
B | 0005886 | cellular_component | plasma membrane |
B | 0007338 | biological_process | single fertilization |
B | 0016020 | cellular_component | membrane |
B | 0016740 | molecular_function | transferase activity |
B | 0016787 | molecular_function | hydrolase activity |
B | 0016849 | molecular_function | phosphorus-oxygen lyase activity |
B | 0030890 | biological_process | positive regulation of B cell proliferation |
B | 0031410 | cellular_component | cytoplasmic vesicle |
B | 0061809 | molecular_function | NAD+ nucleotidase, cyclic ADP-ribose generating |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE N1C A 301 |
Chain | Residue |
A | TRP77 |
A | HOH302 |
A | HOH312 |
A | HOH343 |
A | HOH385 |
A | HOH438 |
A | HOH475 |
A | HOH691 |
A | LEU97 |
A | GLU98 |
A | PHE128 |
A | ARG136 |
A | TRP140 |
A | SER144 |
A | PHE174 |
A | HOH286 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1r16 |
Chain | Residue | Details |
A | GLU98 | |
A | GLY179 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1r16 |
Chain | Residue | Details |
B | GLU98 | |
B | GLY179 |
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 607 |
Chain | Residue | Details |
A | GLU98 | electrostatic stabiliser |
A | PHE174 | hydrophobic interaction |
A | GLY179 | covalent catalysis, covalently attached, nucleophile |
site_id | MCSA2 |
Number of Residues | 3 |
Details | M-CSA 607 |
Chain | Residue | Details |
B | GLU98 | electrostatic stabiliser |
B | PHE174 | hydrophobic interaction |
B | GLY179 | covalent catalysis, covalently attached, nucleophile |