Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004392 | molecular_function | heme oxygenase (decyclizing) activity |
A | 0006788 | biological_process | heme oxidation |
A | 0006979 | biological_process | response to oxidative stress |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0020037 | molecular_function | heme binding |
A | 0042167 | biological_process | heme catabolic process |
A | 0046872 | molecular_function | metal ion binding |
B | 0004392 | molecular_function | heme oxygenase (decyclizing) activity |
B | 0006788 | biological_process | heme oxidation |
B | 0006979 | biological_process | response to oxidative stress |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0020037 | molecular_function | heme binding |
B | 0042167 | biological_process | heme catabolic process |
B | 0046872 | molecular_function | metal ion binding |
C | 0004392 | molecular_function | heme oxygenase (decyclizing) activity |
C | 0006788 | biological_process | heme oxidation |
C | 0006979 | biological_process | response to oxidative stress |
C | 0016491 | molecular_function | oxidoreductase activity |
C | 0020037 | molecular_function | heme binding |
C | 0042167 | biological_process | heme catabolic process |
C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE HEM A 901 |
Chain | Residue |
A | LYS13 |
A | PHE201 |
A | ASN204 |
A | PHE208 |
A | HOH235 |
A | HOH361 |
A | HOH419 |
A | DTV2001 |
A | HIS20 |
A | ALA23 |
A | MET29 |
A | TYR130 |
A | VAL131 |
A | GLY135 |
A | VAL142 |
A | ARG177 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
Chain | Residue |
A | SER26 |
A | THR27 |
A | HIS205 |
A | HOH279 |
A | HOH286 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 1005 |
Chain | Residue |
A | ARG99 |
A | ILE100 |
A | THR101 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE DTV A 2001 |
Chain | Residue |
A | ARG132 |
A | GLY135 |
A | ASP136 |
A | GLY139 |
A | GLY140 |
A | HOH326 |
A | HEM901 |
site_id | AC5 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE HEM B 902 |
Chain | Residue |
B | HOH25 |
B | HOH185 |
B | LYS313 |
B | HIS320 |
B | ALA323 |
B | MET329 |
B | LEU333 |
B | TYR430 |
B | VAL431 |
B | GLY435 |
B | SER438 |
B | GLY439 |
B | ARG477 |
B | PHE501 |
B | ASN504 |
B | PHE508 |
B | DTV2002 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 1002 |
Chain | Residue |
B | HOH18 |
B | VAL382 |
B | ARG385 |
B | GLY459 |
B | HOH532 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 1003 |
Chain | Residue |
B | HOH67 |
B | HOH289 |
B | LYS470 |
B | LYS473 |
B | ARG477 |
site_id | AC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 1004 |
Chain | Residue |
B | HOH196 |
B | SER326 |
B | THR327 |
B | HIS505 |
B | ALA509 |
site_id | AC9 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 B 1008 |
Chain | Residue |
B | HOH61 |
B | HOH213 |
B | GLY367 |
B | ALA369 |
B | GLU370 |
B | SER371 |
B | HOH516 |
site_id | BC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE DTV B 2002 |
Chain | Residue |
B | HOH3 |
B | HOH5 |
B | HOH130 |
B | MET329 |
B | ARG432 |
B | GLY435 |
B | GLY439 |
B | ILE443 |
B | PHE508 |
B | HEM902 |
site_id | BC2 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE HEM C 903 |
Chain | Residue |
C | HOH158 |
C | HOH226 |
C | LYS613 |
C | HIS620 |
C | ALA623 |
C | GLU624 |
C | TYR730 |
C | VAL731 |
C | LEU734 |
C | GLY735 |
C | SER738 |
C | GLY739 |
C | VAL742 |
C | ILE743 |
C | ARG777 |
C | PHE801 |
C | ASN804 |
C | PHE808 |
C | DTV2003 |
site_id | BC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 C 1009 |
Chain | Residue |
C | SER626 |
C | THR627 |
C | PHE628 |
C | HIS805 |
C | ALA809 |
site_id | BC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 C 1010 |
Chain | Residue |
C | HOH212 |
C | HOH356 |
C | GLY667 |
C | ALA669 |
C | GLU670 |
C | SER671 |
site_id | BC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 C 1011 |
Chain | Residue |
C | HOH403 |
C | VAL682 |
C | ARG685 |
C | GLY759 |
site_id | BC6 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE DTV C 2003 |
Chain | Residue |
C | HOH118 |
C | HOH202 |
C | HOH346 |
C | MET629 |
C | ARG732 |
C | GLY735 |
C | ASP736 |
C | GLY739 |
C | PHE808 |
C | HEM903 |
Functional Information from PROSITE/UniProt
site_id | PS00593 |
Number of Residues | 11 |
Details | HEME_OXYGENASE Heme oxygenase signature. LVAHHYVRYLG |
Chain | Residue | Details |
A | LEU125-GLY135 | |