Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004392 | molecular_function | heme oxygenase (decyclizing) activity |
| A | 0006788 | biological_process | heme oxidation |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0042167 | biological_process | heme catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004392 | molecular_function | heme oxygenase (decyclizing) activity |
| B | 0006788 | biological_process | heme oxidation |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0042167 | biological_process | heme catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004392 | molecular_function | heme oxygenase (decyclizing) activity |
| C | 0006788 | biological_process | heme oxidation |
| C | 0006979 | biological_process | response to oxidative stress |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0020037 | molecular_function | heme binding |
| C | 0042167 | biological_process | heme catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM A 901 |
| Chain | Residue |
| A | LYS13 |
| A | PHE201 |
| A | ASN204 |
| A | PHE208 |
| A | HOH235 |
| A | HOH361 |
| A | HOH419 |
| A | DTV2001 |
| A | HIS20 |
| A | ALA23 |
| A | MET29 |
| A | TYR130 |
| A | VAL131 |
| A | GLY135 |
| A | VAL142 |
| A | ARG177 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | SER26 |
| A | THR27 |
| A | HIS205 |
| A | HOH279 |
| A | HOH286 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1005 |
| Chain | Residue |
| A | ARG99 |
| A | ILE100 |
| A | THR101 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DTV A 2001 |
| Chain | Residue |
| A | ARG132 |
| A | GLY135 |
| A | ASP136 |
| A | GLY139 |
| A | GLY140 |
| A | HOH326 |
| A | HEM901 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM B 902 |
| Chain | Residue |
| B | HOH25 |
| B | HOH185 |
| B | LYS313 |
| B | HIS320 |
| B | ALA323 |
| B | MET329 |
| B | LEU333 |
| B | TYR430 |
| B | VAL431 |
| B | GLY435 |
| B | SER438 |
| B | GLY439 |
| B | ARG477 |
| B | PHE501 |
| B | ASN504 |
| B | PHE508 |
| B | DTV2002 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1002 |
| Chain | Residue |
| B | HOH18 |
| B | VAL382 |
| B | ARG385 |
| B | GLY459 |
| B | HOH532 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1003 |
| Chain | Residue |
| B | HOH67 |
| B | HOH289 |
| B | LYS470 |
| B | LYS473 |
| B | ARG477 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1004 |
| Chain | Residue |
| B | HOH196 |
| B | SER326 |
| B | THR327 |
| B | HIS505 |
| B | ALA509 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1008 |
| Chain | Residue |
| B | HOH61 |
| B | HOH213 |
| B | GLY367 |
| B | ALA369 |
| B | GLU370 |
| B | SER371 |
| B | HOH516 |
| site_id | BC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE DTV B 2002 |
| Chain | Residue |
| B | HOH3 |
| B | HOH5 |
| B | HOH130 |
| B | MET329 |
| B | ARG432 |
| B | GLY435 |
| B | GLY439 |
| B | ILE443 |
| B | PHE508 |
| B | HEM902 |
| site_id | BC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM C 903 |
| Chain | Residue |
| C | HOH158 |
| C | HOH226 |
| C | LYS613 |
| C | HIS620 |
| C | ALA623 |
| C | GLU624 |
| C | TYR730 |
| C | VAL731 |
| C | LEU734 |
| C | GLY735 |
| C | SER738 |
| C | GLY739 |
| C | VAL742 |
| C | ILE743 |
| C | ARG777 |
| C | PHE801 |
| C | ASN804 |
| C | PHE808 |
| C | DTV2003 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1009 |
| Chain | Residue |
| C | SER626 |
| C | THR627 |
| C | PHE628 |
| C | HIS805 |
| C | ALA809 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1010 |
| Chain | Residue |
| C | HOH212 |
| C | HOH356 |
| C | GLY667 |
| C | ALA669 |
| C | GLU670 |
| C | SER671 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1011 |
| Chain | Residue |
| C | HOH403 |
| C | VAL682 |
| C | ARG685 |
| C | GLY759 |
| site_id | BC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE DTV C 2003 |
| Chain | Residue |
| C | HOH118 |
| C | HOH202 |
| C | HOH346 |
| C | MET629 |
| C | ARG732 |
| C | GLY735 |
| C | ASP736 |
| C | GLY739 |
| C | PHE808 |
| C | HEM903 |
Functional Information from PROSITE/UniProt
| site_id | PS00593 |
| Number of Residues | 11 |
| Details | HEME_OXYGENASE Heme oxygenase signature. LVAHHYVRYLG |
| Chain | Residue | Details |
| A | LEU125-GLY135 | |
