3I8D

The Pairing Geometry of the Hydrophobic Thymine Analog 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray Crystallography

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity
C	0003676	molecular_function	nucleic acid binding
C	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 601

Chain	Residue
A	HOH25
A	TYR83
A	VAL114
A	HIS115
A	ARG118

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 602

Chain	Residue
C	HOH243
C	GOL603
C	HIS115
C	ARG118
C	ALA165
C	HOH215

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 603

Chain	Residue
C	HIS115
C	TYR119
C	GLU122
C	HOH197
C	HOH217
C	GOL602

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 604

Chain	Residue
C	GLY73
C	SER74
C	GLU82
C	TYR193
D	DG12

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:15989951

Chain	Residue	Details
A	ASP71
A	GLU109
A	ASN132
A	ASP192
C	ASP71
C	GLU109
C	ASN132
C	ASP192

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