3I6E
CRYSTAL STRUCTURE OF MUCONATE LACTONIZING ENZYME FROM Ruegeria pomeroyi.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006518 | biological_process | peptide metabolic process |
| A | 0009063 | biological_process | amino acid catabolic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016854 | molecular_function | racemase and epimerase activity |
| A | 0018849 | molecular_function | muconate cycloisomerase activity |
| A | 0018850 | molecular_function | chloromuconate cycloisomerase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0006518 | biological_process | peptide metabolic process |
| B | 0009063 | biological_process | amino acid catabolic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016854 | molecular_function | racemase and epimerase activity |
| B | 0018849 | molecular_function | muconate cycloisomerase activity |
| B | 0018850 | molecular_function | chloromuconate cycloisomerase activity |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0006518 | biological_process | peptide metabolic process |
| C | 0009063 | biological_process | amino acid catabolic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0016854 | molecular_function | racemase and epimerase activity |
| C | 0018849 | molecular_function | muconate cycloisomerase activity |
| C | 0018850 | molecular_function | chloromuconate cycloisomerase activity |
| C | 0030145 | molecular_function | manganese ion binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0006518 | biological_process | peptide metabolic process |
| D | 0009063 | biological_process | amino acid catabolic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0016854 | molecular_function | racemase and epimerase activity |
| D | 0018849 | molecular_function | muconate cycloisomerase activity |
| D | 0018850 | molecular_function | chloromuconate cycloisomerase activity |
| D | 0030145 | molecular_function | manganese ion binding |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0006518 | biological_process | peptide metabolic process |
| E | 0009063 | biological_process | amino acid catabolic process |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0016854 | molecular_function | racemase and epimerase activity |
| E | 0018849 | molecular_function | muconate cycloisomerase activity |
| E | 0018850 | molecular_function | chloromuconate cycloisomerase activity |
| E | 0030145 | molecular_function | manganese ion binding |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0006518 | biological_process | peptide metabolic process |
| F | 0009063 | biological_process | amino acid catabolic process |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0016854 | molecular_function | racemase and epimerase activity |
| F | 0018849 | molecular_function | muconate cycloisomerase activity |
| F | 0018850 | molecular_function | chloromuconate cycloisomerase activity |
| F | 0030145 | molecular_function | manganese ion binding |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0006518 | biological_process | peptide metabolic process |
| G | 0009063 | biological_process | amino acid catabolic process |
| G | 0016853 | molecular_function | isomerase activity |
| G | 0016854 | molecular_function | racemase and epimerase activity |
| G | 0018849 | molecular_function | muconate cycloisomerase activity |
| G | 0018850 | molecular_function | chloromuconate cycloisomerase activity |
| G | 0030145 | molecular_function | manganese ion binding |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0006518 | biological_process | peptide metabolic process |
| H | 0009063 | biological_process | amino acid catabolic process |
| H | 0016853 | molecular_function | isomerase activity |
| H | 0016854 | molecular_function | racemase and epimerase activity |
| H | 0018849 | molecular_function | muconate cycloisomerase activity |
| H | 0018850 | molecular_function | chloromuconate cycloisomerase activity |
| H | 0030145 | molecular_function | manganese ion binding |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 386 |
| Chain | Residue |
| A | ASP198 |
| A | GLU224 |
| A | ASP249 |
| A | HOH1011 |
| A | HOH1012 |
| A | HOH1013 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 387 |
| Chain | Residue |
| A | HOH419 |
| A | HOH427 |
| A | HOH579 |
| A | ARG239 |
| A | THR242 |
| A | HOH406 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 386 |
| Chain | Residue |
| B | ASP198 |
| B | GLU224 |
| B | ASP249 |
| B | HOH1021 |
| B | HOH1022 |
| B | HOH1023 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 387 |
| Chain | Residue |
| B | ARG239 |
| B | THR242 |
| B | HOH390 |
| B | HOH413 |
| B | HOH417 |
| B | HOH439 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 386 |
| Chain | Residue |
| C | ASP198 |
| C | GLU224 |
| C | ASP249 |
| C | HOH1031 |
| C | HOH1032 |
| C | HOH1033 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 387 |
| Chain | Residue |
| C | ARG239 |
| C | THR242 |
| C | HOH400 |
| C | HOH412 |
| C | HOH464 |
| C | HOH932 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 386 |
| Chain | Residue |
| D | ASP198 |
| D | GLU224 |
| D | ASP249 |
| D | HOH1041 |
| D | HOH1042 |
| D | HOH1043 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA D 387 |
| Chain | Residue |
| D | ARG239 |
| D | THR242 |
| D | HOH402 |
| D | HOH582 |
| D | HOH619 |
| D | HOH772 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG E 386 |
| Chain | Residue |
| E | ASP198 |
| E | GLU224 |
| E | ASP249 |
| E | HOH1051 |
| E | HOH1052 |
| E | HOH1053 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA E 387 |
| Chain | Residue |
| E | ARG239 |
| E | THR242 |
| E | HOH397 |
| E | HOH398 |
| E | HOH402 |
| E | HOH607 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG F 386 |
| Chain | Residue |
| F | ASP198 |
| F | GLU224 |
| F | ASP249 |
| F | HOH1061 |
| F | HOH1062 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA F 387 |
| Chain | Residue |
| F | ARG239 |
| F | THR242 |
| F | HOH396 |
| F | HOH404 |
| F | HOH428 |
| F | HOH664 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG G 386 |
| Chain | Residue |
| G | ASP198 |
| G | GLU224 |
| G | ASP249 |
| G | HOH1071 |
| G | HOH1072 |
| G | HOH1073 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA G 387 |
| Chain | Residue |
| G | ARG239 |
| G | THR242 |
| G | HOH399 |
| G | HOH430 |
| G | HOH448 |
| G | HOH808 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG H 386 |
| Chain | Residue |
| H | ASP198 |
| H | GLU224 |
| H | ASP249 |
| H | HOH1081 |
| H | HOH1082 |
| H | HOH1083 |
| H | HOH1085 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA H 387 |
| Chain | Residue |
| H | ARG239 |
| H | THR242 |
| H | HOH392 |
| H | HOH396 |
| H | HOH643 |
| H | HOH736 |
Functional Information from PROSITE/UniProt
| site_id | PS00908 |
| Number of Residues | 26 |
| Details | MR_MLE_1 Mandelate racemase / muconate lactonizing enzyme family signature 1. AkAALDsALlDLaGRisnlPVwaLLG |
| Chain | Residue | Details |
| A | ALA106-GLY131 |
| site_id | PS00909 |
| Number of Residues | 32 |
| Details | MR_MLE_2 Mandelate racemase / muconate lactonizing enzyme family signature 2. VrvDyNqgleideAvprvldVaqfqpdfIEQP |
| Chain | Residue | Details |
| A | VAL195-PRO226 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| A | LYS170 | |
| A | GLU327 | |
| A | LYS168 |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| B | LYS273 | |
| B | LYS170 |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| C | LYS273 | |
| C | LYS170 |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| D | LYS273 | |
| D | LYS170 |
| site_id | CSA13 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| E | LYS273 | |
| E | LYS170 |
| site_id | CSA14 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| F | LYS273 | |
| F | LYS170 |
| site_id | CSA15 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| G | LYS273 | |
| G | LYS170 |
| site_id | CSA16 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| H | LYS273 | |
| H | LYS170 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| B | LYS170 | |
| B | GLU327 | |
| B | LYS168 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| C | LYS170 | |
| C | GLU327 | |
| C | LYS168 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| D | LYS170 | |
| D | GLU327 | |
| D | LYS168 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| E | LYS170 | |
| E | GLU327 | |
| E | LYS168 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| F | LYS170 | |
| F | GLU327 | |
| F | LYS168 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| G | LYS170 | |
| G | GLU327 | |
| G | LYS168 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| H | LYS170 | |
| H | GLU327 | |
| H | LYS168 |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1muc |
| Chain | Residue | Details |
| A | LYS273 | |
| A | LYS170 |
