Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3I6E

CRYSTAL STRUCTURE OF MUCONATE LACTONIZING ENZYME FROM Ruegeria pomeroyi.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0009063	biological_process	amino acid catabolic process
A	0016853	molecular_function	isomerase activity
A	0018849	molecular_function	muconate cycloisomerase activity
A	0018850	molecular_function	chloromuconate cycloisomerase activity
A	0019439	biological_process	obsolete aromatic compound catabolic process
A	0030145	molecular_function	manganese ion binding
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0009063	biological_process	amino acid catabolic process
B	0016853	molecular_function	isomerase activity
B	0018849	molecular_function	muconate cycloisomerase activity
B	0018850	molecular_function	chloromuconate cycloisomerase activity
B	0019439	biological_process	obsolete aromatic compound catabolic process
B	0030145	molecular_function	manganese ion binding
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0009063	biological_process	amino acid catabolic process
C	0016853	molecular_function	isomerase activity
C	0018849	molecular_function	muconate cycloisomerase activity
C	0018850	molecular_function	chloromuconate cycloisomerase activity
C	0019439	biological_process	obsolete aromatic compound catabolic process
C	0030145	molecular_function	manganese ion binding
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0009063	biological_process	amino acid catabolic process
D	0016853	molecular_function	isomerase activity
D	0018849	molecular_function	muconate cycloisomerase activity
D	0018850	molecular_function	chloromuconate cycloisomerase activity
D	0019439	biological_process	obsolete aromatic compound catabolic process
D	0030145	molecular_function	manganese ion binding
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0003824	molecular_function	catalytic activity
E	0009063	biological_process	amino acid catabolic process
E	0016853	molecular_function	isomerase activity
E	0018849	molecular_function	muconate cycloisomerase activity
E	0018850	molecular_function	chloromuconate cycloisomerase activity
E	0019439	biological_process	obsolete aromatic compound catabolic process
E	0030145	molecular_function	manganese ion binding
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0003824	molecular_function	catalytic activity
F	0009063	biological_process	amino acid catabolic process
F	0016853	molecular_function	isomerase activity
F	0018849	molecular_function	muconate cycloisomerase activity
F	0018850	molecular_function	chloromuconate cycloisomerase activity
F	0019439	biological_process	obsolete aromatic compound catabolic process
F	0030145	molecular_function	manganese ion binding
F	0046872	molecular_function	metal ion binding
G	0000287	molecular_function	magnesium ion binding
G	0003824	molecular_function	catalytic activity
G	0009063	biological_process	amino acid catabolic process
G	0016853	molecular_function	isomerase activity
G	0018849	molecular_function	muconate cycloisomerase activity
G	0018850	molecular_function	chloromuconate cycloisomerase activity
G	0019439	biological_process	obsolete aromatic compound catabolic process
G	0030145	molecular_function	manganese ion binding
G	0046872	molecular_function	metal ion binding
H	0000287	molecular_function	magnesium ion binding
H	0003824	molecular_function	catalytic activity
H	0009063	biological_process	amino acid catabolic process
H	0016853	molecular_function	isomerase activity
H	0018849	molecular_function	muconate cycloisomerase activity
H	0018850	molecular_function	chloromuconate cycloisomerase activity
H	0019439	biological_process	obsolete aromatic compound catabolic process
H	0030145	molecular_function	manganese ion binding
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 386

Chain	Residue
A	ASP198
A	GLU224
A	ASP249
A	HOH1011
A	HOH1012
A	HOH1013

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 387

Chain	Residue
A	HOH419
A	HOH427
A	HOH579
A	ARG239
A	THR242
A	HOH406

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 386

Chain	Residue
B	ASP198
B	GLU224
B	ASP249
B	HOH1021
B	HOH1022
B	HOH1023

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA B 387

Chain	Residue
B	ARG239
B	THR242
B	HOH390
B	HOH413
B	HOH417
B	HOH439

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 386

Chain	Residue
C	ASP198
C	GLU224
C	ASP249
C	HOH1031
C	HOH1032
C	HOH1033

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA C 387

Chain	Residue
C	ARG239
C	THR242
C	HOH400
C	HOH412
C	HOH464
C	HOH932

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 386

Chain	Residue
D	ASP198
D	GLU224
D	ASP249
D	HOH1041
D	HOH1042
D	HOH1043

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA D 387

Chain	Residue
D	ARG239
D	THR242
D	HOH402
D	HOH582
D	HOH619
D	HOH772

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG E 386

Chain	Residue
E	ASP198
E	GLU224
E	ASP249
E	HOH1051
E	HOH1052
E	HOH1053

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA E 387

Chain	Residue
E	ARG239
E	THR242
E	HOH397
E	HOH398
E	HOH402
E	HOH607

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG F 386

Chain	Residue
F	ASP198
F	GLU224
F	ASP249
F	HOH1061
F	HOH1062

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA F 387

Chain	Residue
F	ARG239
F	THR242
F	HOH396
F	HOH404
F	HOH428
F	HOH664

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG G 386

Chain	Residue
G	ASP198
G	GLU224
G	ASP249
G	HOH1071
G	HOH1072
G	HOH1073

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA G 387

Chain	Residue
G	ARG239
G	THR242
G	HOH399
G	HOH430
G	HOH448
G	HOH808

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG H 386

Chain	Residue
H	ASP198
H	GLU224
H	ASP249
H	HOH1081
H	HOH1082
H	HOH1083
H	HOH1085

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA H 387

Chain	Residue
H	ARG239
H	THR242
H	HOH392
H	HOH396
H	HOH643
H	HOH736

Functional Information from PROSITE/UniProt

site_id	PS00908
Number of Residues	26
Details	MR_MLE_1 Mandelate racemase / muconate lactonizing enzyme family signature 1. AkAALDsALlDLaGRisnlPVwaLLG

Chain	Residue	Details
A	ALA106-GLY131

site_id	PS00909
Number of Residues	32
Details	MR_MLE_2 Mandelate racemase / muconate lactonizing enzyme family signature 2. VrvDyNqgleideAvprvldVaqfqpdfIEQP

Chain	Residue	Details
A	VAL195-PRO226

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)