Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3I53

Crystal structure of an O-methyltransferase (NcsB1) from neocarzinostatin biosynthesis in complex with S-adenosyl-L-homocysteine (SAH)

Functional Information from GO Data
ChainGOidnamespacecontents
A0008168molecular_functionmethyltransferase activity
A0008171molecular_functionO-methyltransferase activity
A0017000biological_processantibiotic biosynthetic process
A0032259biological_processmethylation
B0008168molecular_functionmethyltransferase activity
B0008171molecular_functionO-methyltransferase activity
B0017000biological_processantibiotic biosynthetic process
B0032259biological_processmethylation
Functional Information from PDB Data
site_idAC1
Number of Residues20
DetailsBINDING SITE FOR RESIDUE SAH A 401
ChainResidue
ATRP133
APHE228
ASER242
AASP247
ATRP248
AHOH537
AHOH540
AHOH556
AHOH609
AHOH692
AHOH709
APHE146
AHOH769
AHIS153
AGLY177
AGLY179
AASP200
ALEU201
AGLY226
ASER227

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE SAH B 401
ChainResidue
BTRP133
BASP175
BGLY177
BGLY178
BGLY179
BASP200
BLEU201
BPRO204
BGLY226
BSER227
BPHE228
BSER242
BALA243
BASP247
BTRP248
BHOH575
BHOH659
BHOH754

site_idAC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE GOL B 402
ChainResidue
BMET150
BHOH753

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU01020
ChainResidueDetails
AHIS246
BHIS246

site_idSWS_FT_FI2
Number of Residues16
DetailsBINDING: BINDING => ECO:0000269|PubMed:19702337
ChainResidueDetails
AARG11
BTRP133
BHIS153
BASP175
BGLY177
BSER227
BSER242
BASP247
ATRP133
AHIS153
AASP175
AGLY177
ASER227
ASER242
AASP247
BARG11

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01020, ECO:0000269|PubMed:19702337
ChainResidueDetails
AASP200
BASP200

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1kyw
ChainResidueDetails
AHIS246

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1kyw
ChainResidueDetails
BHIS246

227344

PDB entries from 2024-11-13

PDB statisticsPDBj update infoContact PDBjnumon