3I3X

Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008610	biological_process	lipid biosynthetic process
A	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
A	0009245	biological_process	lipid A biosynthetic process
A	0016746	molecular_function	acyltransferase activity
B	0008610	biological_process	lipid biosynthetic process
B	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
B	0009245	biological_process	lipid A biosynthetic process
B	0016746	molecular_function	acyltransferase activity
C	0008610	biological_process	lipid biosynthetic process
C	0008780	molecular_function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
C	0009245	biological_process	lipid A biosynthetic process
C	0016746	molecular_function	acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE U22 A 901

Chain	Residue
A	GLN68
A	VAL154
A	HIS155
A	GLN156
A	PHE157
A	MET165
A	ASN193
A	VAL195
A	GLY196
A	ARG199
A	HOH260
A	MET113
A	HIS117
A	GLY119
A	HIS120
A	THR131
A	ALA137
A	GLY138
A	PHE147

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site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE U22 B 901

Chain	Residue
B	GLN68
B	ASP69
B	MET113
B	HIS117
B	HIS120
B	HIS132
B	ALA137
B	GLY138
B	PHE147
B	ALA153
B	HIS155
B	GLN156
B	MET165
B	ASN193
B	VAL195
B	GLY196
B	ARG199
B	HOH260

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site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE U22 C 901

Chain	Residue
C	GLN68
C	LEU70
C	MET113
C	HIS117
C	HIS120
C	THR131
C	HIS132
C	ALA137
C	GLY138
C	HIS139
C	VAL154
C	HIS155
C	GLN156
C	PHE157
C	MET165
C	ASN193
C	VAL195
C	GLY196
C	ARG199
C	HOH424
C	HOH594

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