3I3X
Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0008610 | biological_process | lipid biosynthetic process |
| B | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| C | 0005829 | cellular_component | cytosol |
| C | 0008610 | biological_process | lipid biosynthetic process |
| C | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| C | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE U22 A 901 |
| Chain | Residue |
| A | GLN68 |
| A | VAL154 |
| A | HIS155 |
| A | GLN156 |
| A | PHE157 |
| A | MET165 |
| A | ASN193 |
| A | VAL195 |
| A | GLY196 |
| A | ARG199 |
| A | HOH260 |
| A | MET113 |
| A | HIS117 |
| A | GLY119 |
| A | HIS120 |
| A | THR131 |
| A | ALA137 |
| A | GLY138 |
| A | PHE147 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE U22 B 901 |
| Chain | Residue |
| B | GLN68 |
| B | ASP69 |
| B | MET113 |
| B | HIS117 |
| B | HIS120 |
| B | HIS132 |
| B | ALA137 |
| B | GLY138 |
| B | PHE147 |
| B | ALA153 |
| B | HIS155 |
| B | GLN156 |
| B | MET165 |
| B | ASN193 |
| B | VAL195 |
| B | GLY196 |
| B | ARG199 |
| B | HOH260 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE U22 C 901 |
| Chain | Residue |
| C | GLN68 |
| C | LEU70 |
| C | MET113 |
| C | HIS117 |
| C | HIS120 |
| C | THR131 |
| C | HIS132 |
| C | ALA137 |
| C | GLY138 |
| C | HIS139 |
| C | VAL154 |
| C | HIS155 |
| C | GLN156 |
| C | PHE157 |
| C | MET165 |
| C | ASN193 |
| C | VAL195 |
| C | GLY196 |
| C | ARG199 |
| C | HOH424 |
| C | HOH594 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| A | HIS120 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| B | HIS120 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lxa |
| Chain | Residue | Details |
| C | HIS120 |
