3HYS
Structure of Rv0554 from Mycobacterium tuberculosis complexed with Malonic Acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MLA A 5188 |
| Chain | Residue |
| A | THR27 |
| A | ARG146 |
| A | TRP172 |
| A | LEU240 |
| A | EDO264 |
| A | HOH405 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TRS A 263 |
| Chain | Residue |
| A | MET88 |
| A | ARG113 |
| A | GLN183 |
| A | LEU184 |
| A | HOH476 |
| A | GLY20 |
| A | ARG21 |
| A | SER87 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 264 |
| Chain | Residue |
| A | ARG21 |
| A | GLY23 |
| A | HOH400 |
| A | MLA5188 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 265 |
| Chain | Residue |
| A | ALA161 |
| A | ASP164 |
| A | TRP165 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 266 |
| Chain | Residue |
| A | PHE46 |
| A | ASN48 |
| A | ARG49 |
| A | MET65 |
| A | ASP68 |
| A | THR69 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 267 |
| Chain | Residue |
| A | ALA223 |
| A | LEU226 |
| A | GLY229 |
| A | HOH308 |
| A | HOH309 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE MLA B 5188 |
| Chain | Residue |
| B | GLY20 |
| B | ARG21 |
| B | SER87 |
| B | MET88 |
| B | ARG120 |
| B | PHE123 |
| B | HIS239 |
| B | HOH300 |
| B | HOH301 |
| B | HOH302 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 263 |
| Chain | Residue |
| B | ARG146 |
| B | HOH307 |
| B | HOH417 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 264 |
| Chain | Residue |
| B | GLY22 |
| B | ALA24 |
| B | ARG26 |
| B | TRP172 |
| B | PRO173 |
| B | HOH417 |
| B | HOH418 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 265 |
| Chain | Residue |
| B | ALA119 |
| B | HOH295 |
| B | HOH296 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 266 |
| Chain | Residue |
| B | GLY12 |
| B | ASP13 |
| B | GLY40 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 267 |
| Chain | Residue |
| B | ALA223 |
| B | ASP224 |
| B | LEU226 |
| B | GLY229 |
| B | HOH282 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"20693690","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20693690","evidenceCode":"ECO:0000305"},{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"submission","publicationDate":"JUN-2009","submissionDatabase":"PDB data bank","title":"The structure of Rv0554 from Mycobacterium tuberculosis.","authors":["Johnston J.M.","Baker E.N."]}}]} |
| Chain | Residue | Details |
