Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 601 |
| Chain | Residue |
| A | ASP415 |
| A | ASP417 |
| A | ASN419 |
| A | TYR421 |
| A | GLU423 |
| A | GLU426 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 602 |
| Chain | Residue |
| A | GLN374 |
| A | GLU379 |
| A | HOH508 |
| A | ASP368 |
| A | ASN370 |
| A | ASP372 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 603 |
| Chain | Residue |
| A | ASP451 |
| A | ASP453 |
| A | SER455 |
| A | LYS457 |
| A | GLU462 |
| A | HOH587 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 604 |
| Chain | Residue |
| A | ASP485 |
| A | ASN487 |
| A | ASP489 |
| A | GLU491 |
| A | GLU496 |
| A | HOH588 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ANP A 605 |
| Chain | Residue |
| A | LEU57 |
| A | GLU64 |
| A | VAL65 |
| A | ALA78 |
| A | LYS80 |
| A | GLU129 |
| A | TYR131 |
| A | GLU135 |
| A | LEU181 |
| A | ASP195 |
| A | HOH528 |
| A | HOH529 |
| A | GOL611 |
| A | HOH700 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 606 |
| Chain | Residue |
| A | ARG173 |
| A | MET208 |
| A | LYS209 |
| A | ASP210 |
| A | TYR227 |
| A | HOH523 |
| A | HOH670 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 607 |
| Chain | Residue |
| A | LYS176 |
| A | HOH537 |
| A | HOH651 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 608 |
| Chain | Residue |
| A | LYS266 |
| A | ASP473 |
| A | SER474 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 609 |
| Chain | Residue |
| A | HIS33 |
| A | TYR256 |
| A | LYS260 |
| A | LYS338 |
| A | HOH512 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 610 |
| Chain | Residue |
| A | THR132 |
| A | SER184 |
| A | LYS185 |
| site_id | BC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 611 |
| Chain | Residue |
| A | LEU57 |
| A | GLY58 |
| A | LYS59 |
| A | GLY60 |
| A | SER61 |
| A | PHE62 |
| A | GLY63 |
| A | GLU64 |
| A | VAL65 |
| A | ANP605 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 612 |
| Chain | Residue |
| A | GLU279 |
| A | SER280 |
| A | SER294 |
| A | HOH517 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGSFGEVIlCkdkitgqe..........CAVK |
| Chain | Residue | Details |
| A | LEU57-LYS80 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IvHrDLKpeNLLL |
| Chain | Residue | Details |
| A | ILE170-LEU182 | |
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DKNGDGQLDraEL |
| Chain | Residue | Details |
| A | ASP368-LEU380 | |
| A | ASP415-PHE427 | |
| A | ASP451-LEU463 | |
| A | ASP485-PHE497 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP174 | |
| A | GLU178 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP174 | |
| A | LYS176 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP174 | |
| A | THR214 | |
| A | LYS176 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASN179 | |
| A | ASP174 | |
| A | LYS176 | |
