3HW4
Crystal structure of avian influenza A virus in complex with TMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0039694 | biological_process | viral RNA genome replication |
| C | 0003723 | molecular_function | RNA binding |
| C | 0039694 | biological_process | viral RNA genome replication |
| D | 0003723 | molecular_function | RNA binding |
| D | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 999 |
| Chain | Residue |
| A | GLU80 |
| A | ASP108 |
| A | TMP257 |
| A | HOH1001 |
| A | HOH1002 |
| A | HOH1003 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TMP A 257 |
| Chain | Residue |
| A | LEU42 |
| A | GLU80 |
| A | ASP108 |
| A | ILE120 |
| A | LYS134 |
| A | HOH333 |
| A | MG999 |
| A | HOH1001 |
| A | HOH1002 |
| A | HOH1041 |
| A | HOH1052 |
| A | ALA20 |
| A | ILE38 |
| A | HIS41 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 999 |
| Chain | Residue |
| B | GLU80 |
| B | ASP108 |
| B | HOH1001 |
| B | HOH1002 |
| B | HOH1003 |
| B | HOH1004 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TMP B 257 |
| Chain | Residue |
| A | GLU23 |
| A | TYR24 |
| A | ARG84 |
| A | PHE105 |
| B | TRP88 |
| B | ASN92 |
| B | LYS104 |
| B | HOH325 |
| B | HOH337 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 999 |
| Chain | Residue |
| C | GLU80 |
| C | ASP108 |
| C | HOH330 |
| C | HOH1001 |
| C | HOH1002 |
| C | HOH1003 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 999 |
| Chain | Residue |
| D | GLU80 |
| D | ASP108 |
| D | TMP257 |
| D | HOH1001 |
| D | HOH1002 |
| D | HOH1003 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TMP D 257 |
| Chain | Residue |
| D | ALA20 |
| D | TYR24 |
| D | ILE38 |
| D | HIS41 |
| D | LEU42 |
| D | GLU80 |
| D | GLY81 |
| D | ASP108 |
| D | GLU119 |
| D | ILE120 |
| D | LYS134 |
| D | MG999 |
| D | HOH1002 |
| D | HOH1003 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 60 |
| Details | Motif: {"description":"Nuclear localization signal 1 (NLS1)","evidences":[{"source":"UniProtKB","id":"P03433","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
