3HT5
Crystal Structure of IlvE a Branched Chain Amino Acid Transaminase from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004084 | molecular_function | branched-chain-amino-acid transaminase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009081 | biological_process | branched-chain amino acid metabolic process |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0009099 | biological_process | L-valine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018272 | biological_process | protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0052654 | molecular_function | L-leucine-2-oxoglutarate transaminase activity |
| A | 0052655 | molecular_function | L-valine-2-oxoglutarate transaminase activity |
| A | 0052656 | molecular_function | L-isoleucine-2-oxoglutarate transaminase activity |
| A | 0071267 | biological_process | L-methionine salvage |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PMP A 6236 |
| Chain | Residue |
| A | ARG101 |
| A | LEU268 |
| A | GLY270 |
| A | ILE271 |
| A | THR272 |
| A | GLY313 |
| A | THR314 |
| A | HOH388 |
| A | HOH423 |
| A | HOH448 |
| A | HOH507 |
| A | ARG194 |
| A | LYS204 |
| A | TYR209 |
| A | GLU240 |
| A | GLY242 |
| A | GLY243 |
| A | MET244 |
| A | ASN245 |
Functional Information from PROSITE/UniProt
| site_id | PS00770 |
| Number of Residues | 34 |
| Details | AA_TRANSFER_CLASS_4 Aminotransferases class-IV signature. EmGgmNIFfvlgsggsar..LvTpelsgsl.LpGItR |
| Chain | Residue | Details |
| A | GLU240-ARG273 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ARG101 | |
| A | TYR209 | |
| A | ILE271 | |
| A | THR314 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine |
| Chain | Residue | Details |
| A | LYS204 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1iyd |
| Chain | Residue | Details |
| A | LYS204 |
