Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 997 |
| Chain | Residue |
| A | GLU473 |
| A | ASN474 |
| A | ARG510 |
| A | SO4998 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 998 |
| Chain | Residue |
| A | ARG510 |
| A | ARG558 |
| A | SO4997 |
| A | HOH134 |
| A | HOH140 |
| A | PHE472 |
| A | GLU473 |
| A | ASN474 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 1 |
| Chain | Residue |
| A | MG2 |
| A | HOH3 |
| A | HIS519 |
| A | HIS553 |
| A | ASP554 |
| A | ASP664 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 2 |
| Chain | Residue |
| A | ZN1 |
| A | HOH3 |
| A | HOH4 |
| A | HOH5 |
| A | ASP554 |
| A | HOH785 |
| A | HOH786 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE PF8 A 999 |
| Chain | Residue |
| A | HOH15 |
| A | HOH108 |
| A | HOH163 |
| A | HOH168 |
| A | TYR514 |
| A | HIS647 |
| A | LEU665 |
| A | VAL668 |
| A | TYR683 |
| A | PHE686 |
| A | PRO702 |
| A | MET703 |
| A | LYS708 |
| A | GLU711 |
| A | VAL712 |
| A | GLY715 |
| A | GLN716 |
| A | PHE719 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGfsNsY |
| Chain | Residue | Details |
| A | HIS553-TYR564 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9Y233","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17228859","evidenceCode":"ECO:0000269"}]} |
