3HQJ

Structure-function analysis of Mycobacterium tuberculosis acyl carrier protein synthase (AcpS).

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0008897	molecular_function	holo-[acyl-carrier-protein] synthase activity
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 131

Chain	Residue
A	HOH132
A	HOH132
A	HOH132
A	HOH133
A	HOH133
A	HOH133

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 134

Chain	Residue
A	HOH137
A	HOH139
A	COA150
A	ASP9
A	HOH135
A	HOH136

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 145

Chain	Residue
A	HIS116
A	HOH146
A	HOH147
A	HOH148
A	COA150

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site_id	AC4
Number of Residues	20
Details	BINDING SITE FOR RESIDUE COA A 150

Chain	Residue
A	ASP9
A	HIS49
A	ARG53
A	LYS62
A	SER65
A	GLY91
A	ARG92
A	PRO93
A	LEU114
A	THR115
A	HIS116
A	MG134
A	HOH136
A	HOH137
A	HOH138
A	HOH139
A	MG145
A	HOH146
A	HOH147
A	HOH151

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19733180","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19733180","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3HQJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1f7l

Chain	Residue	Details
A	LYS62
A	HIS116

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