3HM8

Crystal structure of the C-terminal Hexokinase domain of human HK3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001678	biological_process	intracellular glucose homeostasis
A	0004396	molecular_function	hexokinase activity
A	0005524	molecular_function	ATP binding
A	0005536	molecular_function	D-glucose binding
A	0005975	biological_process	carbohydrate metabolic process
A	0006096	biological_process	glycolytic process
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
B	0001678	biological_process	intracellular glucose homeostasis
B	0004396	molecular_function	hexokinase activity
B	0005524	molecular_function	ATP binding
B	0005536	molecular_function	D-glucose binding
B	0005975	biological_process	carbohydrate metabolic process
B	0006096	biological_process	glycolytic process
B	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
C	0001678	biological_process	intracellular glucose homeostasis
C	0004396	molecular_function	hexokinase activity
C	0005524	molecular_function	ATP binding
C	0005536	molecular_function	D-glucose binding
C	0005975	biological_process	carbohydrate metabolic process
C	0006096	biological_process	glycolytic process
C	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
D	0001678	biological_process	intracellular glucose homeostasis
D	0004396	molecular_function	hexokinase activity
D	0005524	molecular_function	ATP binding
D	0005536	molecular_function	D-glucose binding
D	0005975	biological_process	carbohydrate metabolic process
D	0006096	biological_process	glycolytic process
D	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor

Functional Information from PROSITE/UniProt

site_id	PS00378
Number of Residues	26
Details	HEXOKINASE_1 Hexokinase domain signature. LGFTFSFPcrqlgLDqgiLlnWTKgF

Chain	Residue	Details
A	LEU604-PHE629

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P19367

site_id	SWS_FT_FI2
Number of Residues	20
Details	BINDING: BINDING => ECO:0000269\|Ref.5, ECO:0007744\|PDB:3HM8