3HLX

Crystal Structure of PqqC Active Site Mutant Y175F in Complex with PQQ

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0018189	biological_process	pyrroloquinoline quinone biosynthetic process
A	0033732	molecular_function	pyrroloquinoline-quinone synthase activity
D	0016491	molecular_function	oxidoreductase activity
D	0018189	biological_process	pyrroloquinoline quinone biosynthetic process
D	0033732	molecular_function	pyrroloquinoline-quinone synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE PQQ A 500

Chain	Residue
A	TYR23
A	THR146
A	ILE153
A	HIS154
A	ARG157
A	PHE175
A	ARG179
A	LYS214
A	CL261
A	HOH295
A	HIS24
A	ARG50
A	TYR53
A	GLN54
A	LYS60
A	HIS84
A	TYR128
A	SER144

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 259

Chain	Residue
A	LYS76
A	TRP77
A	ARG80
A	ARG185
A	ASP186
A	HIS189
A	HOH390

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 260

Chain	Residue
A	ARG233
A	HOH407
D	THR226
D	ALA230

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 261

Chain	Residue
A	ALA150
A	HIS154
A	ARG179
A	PQQ500

---

site_id	AC5
Number of Residues	19
Details	BINDING SITE FOR RESIDUE PQQ D 500

Chain	Residue
D	TYR23
D	HIS24
D	ARG50
D	TYR53
D	GLN54
D	ILE57
D	LYS60
D	HIS84
D	TYR128
D	SER144
D	THR146
D	ILE153
D	HIS154
D	ARG157
D	PHE175
D	ARG179
D	LYS214
D	CL261
D	HOH273

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 259

Chain	Residue
D	LYS76
D	TRP77
D	ARG80
D	ARG185
D	ASP186
D	HIS189

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 260

Chain	Residue
A	TYR29
A	ALA32
A	THR226
A	ALA230
D	ARG233
D	HOH403

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL D 261

Chain	Residue
D	ALA150
D	HIS154
D	ARG179
D	PQQ500

---