3HLT

The crystal structure of human haloacid dehalogenase-like hydrolase domain containing 2 (HDHD2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0008150	biological_process	biological_process
A	0016311	biological_process	dephosphorylation
A	0016791	molecular_function	phosphatase activity
A	0019899	molecular_function	enzyme binding
A	0046872	molecular_function	metal ion binding
A	0070062	cellular_component	extracellular exosome
C	0005515	molecular_function	protein binding
C	0008150	biological_process	biological_process
C	0016311	biological_process	dephosphorylation
C	0016791	molecular_function	phosphatase activity
C	0019899	molecular_function	enzyme binding
C	0046872	molecular_function	metal ion binding
C	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 267

Chain	Residue
A	THR48
A	THR49
A	LYS50
A	LEU117
A	HIS144
A	HOH302

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 268

Chain	Residue
A	GLY191

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 269

Chain	Residue
A	ASP204
A	ASP209
A	HOH307
A	HOH314
A	ASP13
A	SER15

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 267

Chain	Residue
C	THR48
C	THR49
C	LYS50
C	LEU117
C	HIS144

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL C 268

Chain	Residue
C	GLY191
C	GLY191
C	THR192
C	GLY193

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA C 269

Chain	Residue
C	ASP13
C	SER15
C	ASP204

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP13
A	ASP204
C	ASP13
C	SER15
C	THR46
C	LYS179
C	ASP204
A	SER15
A	THR46
A	LYS179

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q3UGR5

Chain	Residue	Details
A	LYS50
C	LYS50

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