3HLK

Crystal structure of human mitochondrial acyl-CoA thioesterase (ACOT2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000038	biological_process	very long-chain fatty acid metabolic process
A	0001676	biological_process	long-chain fatty acid metabolic process
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0006631	biological_process	fatty acid metabolic process
A	0006637	biological_process	acyl-CoA metabolic process
A	0016790	molecular_function	thiolester hydrolase activity
A	0047617	molecular_function	fatty acyl-CoA hydrolase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity
B	0000038	biological_process	very long-chain fatty acid metabolic process
B	0001676	biological_process	long-chain fatty acid metabolic process
B	0005515	molecular_function	protein binding
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0005782	cellular_component	peroxisomal matrix
B	0005829	cellular_component	cytosol
B	0006631	biological_process	fatty acid metabolic process
B	0006637	biological_process	acyl-CoA metabolic process
B	0016790	molecular_function	thiolester hydrolase activity
B	0047617	molecular_function	fatty acyl-CoA hydrolase activity
B	0052689	molecular_function	carboxylic ester hydrolase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Charge relay system => ECO:0000303|PubMed:19497300

Chain	Residue	Details
A	SER294
A	ASP388
A	HIS422
B	SER294
B	ASP388
B	HIS422

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q9QYR9

Chain	Residue	Details
A	LYS104
B	LYS104

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q9QYR9

Chain	Residue	Details
A	LYS470
B	LYS470

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