3HER

Human prion protein variant F198S with V129

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
A	0051260	biological_process	protein homooligomerization
B	0016020	cellular_component	membrane
B	0051260	biological_process	protein homooligomerization

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 300

Chain	Residue
A	HIS140
A	ASP147
A	HOH324
A	HOH325
B	HIS177

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD B 301

Chain	Residue
A	HIS177
B	HIS140
B	ASP147
B	HOH438

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Functional Information from PROSITE/UniProt

site_id	PS00291
Number of Residues	16
Details	PRION_1 Prion protein signature 1. AGAAAAGAVVGGLGGY

Chain	Residue	Details
A	ALA113-TYR128

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site_id	PS00706
Number of Residues	19
Details	PRION_2 Prion protein signature 2. EtDvKMMeRVVeQMCitQY

Chain	Residue	Details
A	GLU200-TYR218

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	LIPID: GPI-anchor amidated serine => ECO:0000250|UniProtKB:P04273

Chain	Residue	Details
A	SER230
B	SER230

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12214108

Chain	Residue	Details
A	ASN181
B	ASN181

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19349973

Chain	Residue	Details
A	ASN197
B	ASN197

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