Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004518 | molecular_function | nuclease activity |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004518 | molecular_function | nuclease activity |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0004518 | molecular_function | nuclease activity |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0004518 | molecular_function | nuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE THP A 150 |
| Chain | Residue |
| A | ARG35 |
| A | HOH166 |
| A | HOH200 |
| A | HOH203 |
| A | HOH232 |
| A | HOH245 |
| A | LYS84 |
| A | TYR85 |
| A | ARG87 |
| A | LEU89 |
| A | TYR113 |
| A | HOH155 |
| A | HOH159 |
| A | HOH160 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE THP B 150 |
| Chain | Residue |
| B | ARG35 |
| B | HOH45 |
| B | LYS84 |
| B | TYR85 |
| B | ARG87 |
| B | LEU89 |
| B | TYR113 |
| B | HOH153 |
| B | HOH154 |
| B | HOH163 |
| B | HOH164 |
| B | HOH178 |
| B | HOH208 |
| B | HOH209 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE THP C 150 |
| Chain | Residue |
| C | ARG35 |
| C | LYS84 |
| C | TYR85 |
| C | ARG87 |
| C | LEU89 |
| C | TYR113 |
| C | HOH152 |
| C | HOH158 |
| C | HOH179 |
| C | HOH195 |
| C | HOH200 |
| C | HOH228 |
| C | HOH267 |
| C | HOH296 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE THP D 150 |
| Chain | Residue |
| D | ARG35 |
| D | LYS84 |
| D | TYR85 |
| D | ARG87 |
| D | LEU89 |
| D | HOH155 |
| D | HOH159 |
| D | HOH161 |
| D | HOH191 |
| D | HOH231 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MRD B 151 |
| Chain | Residue |
| B | GLN80 |
| B | LYS116 |
| B | ASN118 |
| D | GLN106 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD A 151 |
| Chain | Residue |
| A | GLN80 |
| A | TYR115 |
| A | LYS116 |
| A | ASN118 |
| A | HOH238 |
| C | GLN106 |
| C | LEU137 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 151 |
| Chain | Residue |
| B | MET26 |
| C | THR13 |
| C | HOH221 |
| C | HOH223 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 152 |
| Chain | Residue |
| A | LYS116 |
| A | HOH212 |
| A | HOH213 |
| A | HOH215 |
| C | HOH215 |
Functional Information from PROSITE/UniProt
| site_id | PS01123 |
| Number of Residues | 25 |
| Details | TNASE_1 Thermonuclease family signature 1. DGDTVkLmykgqpmtf.RLllVDtPE |
| Chain | Residue | Details |
| A | ASP19-GLU43 | |
| site_id | PS01284 |
| Number of Residues | 11 |
| Details | TNASE_2 Thermonuclease family signature 2. DKYGRgLAyIY |
| Chain | Residue | Details |
| A | ASP83-TYR93 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ARG35 | |
| A | GLU43 | |
| A | TYR93 | |
| D | ARG35 | |
| D | GLU43 | |
| D | TYR93 | |
| B | GLU43 | |
| B | TYR93 | |
| C | ARG35 | |
| C | GLU43 | |
| C | TYR93 | |
| B | ARG35 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP21 | |
| A | ASP40 | |
| B | THR41 | |
| C | ASP21 | |
| C | ASP40 | |
| C | THR41 | |
| A | THR41 | |
| D | ASP21 | |
| D | ASP40 | |
| D | THR41 | |
| B | ASP21 | |
| B | ASP40 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 165 |
| Chain | Residue | Details |
| A | ASP21 | metal ligand |
| A | ARG35 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP40 | metal ligand |
| A | THR41 | metal ligand |
| A | GLU43 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | TYR93 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 165 |
| Chain | Residue | Details |
| D | ASP21 | metal ligand |
| D | ARG35 | electrostatic stabiliser, hydrogen bond donor |
| D | ASP40 | metal ligand |
| D | THR41 | metal ligand |
| D | GLU43 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | TYR93 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 6 |
| Details | M-CSA 165 |
| Chain | Residue | Details |
| B | ASP21 | metal ligand |
| B | ARG35 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP40 | metal ligand |
| B | THR41 | metal ligand |
| B | GLU43 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | TYR93 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA4 |
| Number of Residues | 6 |
| Details | M-CSA 165 |
| Chain | Residue | Details |
| C | ASP21 | metal ligand |
| C | ARG35 | electrostatic stabiliser, hydrogen bond donor |
| C | ASP40 | metal ligand |
| C | THR41 | metal ligand |
| C | GLU43 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | TYR93 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
