Functional Information from GO Data
Chain | GOid | namespace | contents |
P | 0004222 | molecular_function | metalloendopeptidase activity |
P | 0005509 | molecular_function | calcium ion binding |
P | 0005576 | cellular_component | extracellular region |
P | 0005615 | cellular_component | extracellular space |
P | 0006508 | biological_process | proteolysis |
P | 0008233 | molecular_function | peptidase activity |
P | 0008237 | molecular_function | metallopeptidase activity |
P | 0008270 | molecular_function | zinc ion binding |
P | 0016787 | molecular_function | hydrolase activity |
P | 0031012 | cellular_component | extracellular matrix |
P | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA P 480 |
Chain | Residue |
P | ARG265 |
P | GLY267 |
P | SER269 |
P | ASP297 |
P | GLY299 |
P | ASP302 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA P 481 |
Chain | Residue |
P | GLU341 |
P | HOH634 |
P | HOH635 |
P | GLY300 |
P | ASP302 |
P | THR339 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA P 482 |
Chain | Residue |
P | GLY346 |
P | GLY348 |
P | ASP350 |
P | GLY363 |
P | ALA365 |
P | ASP368 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA P 483 |
Chain | Residue |
P | ASN355 |
P | ALA357 |
P | ASN359 |
P | GLY372 |
P | ALA374 |
P | ASP377 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA P 484 |
Chain | Residue |
P | GLY364 |
P | GLY366 |
P | ASP368 |
P | GLY381 |
P | ALA383 |
P | ASP386 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA P 485 |
Chain | Residue |
P | HOH10 |
P | GLY382 |
P | GLY384 |
P | ASP386 |
P | GLN408 |
P | ASP412 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA P 487 |
Chain | Residue |
P | GLY373 |
P | GLY375 |
P | ASP377 |
P | ASP395 |
P | ASP402 |
P | HOH636 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL P 1 |
Chain | Residue |
P | ARG265 |
P | GLY267 |
P | SER269 |
P | HOH659 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL P 3 |
Chain | Residue |
P | GLN110 |
P | SER113 |
P | HOH508 |
P | HOH694 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TFTHEIGHAL |
Chain | Residue | Details |
P | THR185-LEU194 | |
site_id | PS00330 |
Number of Residues | 19 |
Details | HEMOLYSIN_CALCIUM Hemolysin-type calcium-binding region signature. DvLyggaGaDtLyGGagrD |
Chain | Residue | Details |
P | ASP368-ASP386 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 17 |
Details | Repeat: {"description":"Hemolysin-type calcium-binding 1"} |
site_id | SWS_FT_FI2 |
Number of Residues | 17 |
Details | Repeat: {"description":"Hemolysin-type calcium-binding 2"} |
site_id | SWS_FT_FI3 |
Number of Residues | 17 |
Details | Repeat: {"description":"Hemolysin-type calcium-binding 3"} |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"}]} |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"}]} |
site_id | SWS_FT_FI6 |
Number of Residues | 31 |
Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1qib |
Chain | Residue | Details |
P | GLU189 | |