3HDA

PrtC methionine mutants: M226A_DESY

Functional Information from GO Data

Chain	GOid	namespace	contents
P	0004222	molecular_function	metalloendopeptidase activity
P	0005509	molecular_function	calcium ion binding
P	0005576	cellular_component	extracellular region
P	0005615	cellular_component	extracellular space
P	0006508	biological_process	proteolysis
P	0008237	molecular_function	metallopeptidase activity
P	0008270	molecular_function	zinc ion binding
P	0031012	cellular_component	extracellular matrix
P	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 480

Chain	Residue
P	ARG265
P	GLY267
P	SER269
P	ASP297
P	GLY299
P	ASP302

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 481

Chain	Residue
P	GLU341
P	HOH634
P	HOH635
P	GLY300
P	ASP302
P	THR339

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 482

Chain	Residue
P	GLY346
P	GLY348
P	ASP350
P	GLY363
P	ALA365
P	ASP368

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 483

Chain	Residue
P	ASN355
P	ALA357
P	ASN359
P	GLY372
P	ALA374
P	ASP377

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 484

Chain	Residue
P	GLY364
P	GLY366
P	ASP368
P	GLY381
P	ALA383
P	ASP386

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 485

Chain	Residue
P	HOH10
P	GLY382
P	GLY384
P	ASP386
P	GLN408
P	ASP412

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 487

Chain	Residue
P	GLY373
P	GLY375
P	ASP377
P	ASP395
P	ASP402
P	HOH636

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL P 1

Chain	Residue
P	ARG265
P	GLY267
P	SER269
P	HOH659

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL P 3

Chain	Residue
P	GLN110
P	SER113
P	HOH508
P	HOH694

---

Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TFTHEIGHAL

Chain	Residue	Details
P	THR185-LEU194

---

site_id	PS00330
Number of Residues	19
Details	HEMOLYSIN_CALCIUM Hemolysin-type calcium-binding region signature. DvLyggaGaDtLyGGagrD

Chain	Residue	Details
P	ASP368-ASP386

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
P	GLU189

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
P	HIS188
P	HIS192
P	TYR228

---

site_id	SWS_FT_FI3
Number of Residues	31
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
P	ARG265
P	GLY348
P	ASP350
P	ASN355
P	ALA357
P	ASN359
P	GLY363
P	GLY364
P	ALA365
P	GLY366
P	ASP368
P	GLY267
P	GLY372
P	GLY373
P	GLY375
P	ASP377
P	GLY381
P	GLY382
P	ALA383
P	GLY384
P	ASP386
P	ASP395
P	ASP297
P	ASP402
P	ASP412
P	GLY299
P	GLY300
P	ASP302
P	THR339
P	GLU341
P	GLY346

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1qib

Chain	Residue	Details
P	GLU189

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