3HC3

BHA10 IgG1 Fab double mutant variant - antibody directed at human LTBR

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT H 218

Chain	Residue
H	TYR33
H	HIS35
H	TRP50
H	SER99
H	HOH264
H	HOH392
H	HOH406
L	TYR94

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN L 214

Chain	Residue
H	HOH351
L	ASN137
L	ASN138
L	ACT217
H	HIS167

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 215

Chain	Residue
H	HIS57
L	ASP151
L	HIS189
L	ACT216

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ACT L 216

Chain	Residue
H	TYR33
H	TRP50
H	ASN55
H	HIS57
H	HOH244
L	ASP151
L	HIS189
L	ZN215
L	HOH347

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site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT L 217

Chain	Residue
H	GLY165
H	HIS167
H	THR186
H	HOH351
L	ASN137
L	ASN138
L	ZN214
L	HOH400

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR197-HIS203
L	TYR192-HIS198

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