3HB2

PrtC methionine mutants: M226I

Functional Information from GO Data

Chain	GOid	namespace	contents
P	0004222	molecular_function	metalloendopeptidase activity
P	0005509	molecular_function	calcium ion binding
P	0005576	cellular_component	extracellular region
P	0005615	cellular_component	extracellular space
P	0006508	biological_process	proteolysis
P	0008233	molecular_function	peptidase activity
P	0008237	molecular_function	metallopeptidase activity
P	0008270	molecular_function	zinc ion binding
P	0016787	molecular_function	hydrolase activity
P	0030198	biological_process	extracellular matrix organization
P	0030574	biological_process	collagen catabolic process
P	0031012	cellular_component	extracellular matrix
P	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 480

Chain	Residue
P	ARG265
P	GLY267
P	SER269
P	ASP297
P	GLY299
P	ASP302

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 481

Chain	Residue
P	GLU341
P	HOH532
P	HOH533
P	GLY300
P	ASP302
P	THR339

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 482

Chain	Residue
P	GLY346
P	GLY348
P	ASP350
P	GLY363
P	ALA365
P	ASP368

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 483

Chain	Residue
P	ASN355
P	ALA357
P	ASN359
P	GLY372
P	ALA374
P	ASP377

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 484

Chain	Residue
P	GLY364
P	GLY366
P	ASP368
P	GLY381
P	ALA383
P	ASP386

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 485

Chain	Residue
P	HOH17
P	GLY382
P	GLY384
P	ASP386
P	GLN408
P	ASP412

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN P 486

Chain	Residue
P	HIS188
P	HIS192
P	HIS198
P	HOH556

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA P 487

Chain	Residue
P	GLY373
P	GLY375
P	ASP377
P	ASP395
P	ASP402
P	HOH535

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL P 1

Chain	Residue
P	ASN355
P	SER356
P	ALA374
P	HOH895
P	HOH981

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL P 3

Chain	Residue
P	TYR146
P	ARG467
P	HOH758

---

Functional Information from PROSITE/UniProt

site_id	PS00330
Number of Residues	19
Details	HEMOLYSIN_CALCIUM Hemolysin-type calcium-binding region signature. DvLyggaGaDtLyGGagrD

Chain	Residue	Details
P	ASP368-ASP386

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
P	ALA189

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
P	HIS188
P	HIS192
P	TYR228

---

site_id	SWS_FT_FI3
Number of Residues	31
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
P	ARG265
P	GLY348
P	ASP350
P	ASN355
P	ALA357
P	ASN359
P	GLY363
P	GLY364
P	ALA365
P	GLY366
P	ASP368
P	GLY267
P	GLY372
P	GLY373
P	GLY375
P	ASP377
P	GLY381
P	GLY382
P	ALA383
P	GLY384
P	ASP386
P	ASP395
P	ASP297
P	ASP402
P	ASP412
P	GLY299
P	GLY300
P	ASP302
P	THR339
P	GLU341
P	GLY346

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