Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016787 | molecular_function | hydrolase activity |
D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE ZN A 500 |
Chain | Residue |
A | ENL0 |
A | ASP271 |
A | ASN303 |
A | HIS352 |
A | HIS427 |
A | ZN501 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN A 501 |
Chain | Residue |
A | ASP271 |
A | ZN500 |
A | ENL0 |
A | ASP242 |
A | HIS244 |
site_id | AC3 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE ENL A 0 |
Chain | Residue |
A | ASP242 |
A | HIS244 |
A | ASP271 |
A | ARG275 |
A | ASN303 |
A | HIS304 |
A | HIS352 |
A | ARG400 |
A | HIS427 |
A | GLU428 |
A | PHE446 |
A | TYR451 |
A | ZN500 |
A | ZN501 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE ZN D 500 |
Chain | Residue |
D | ENL0 |
D | ASP271 |
D | ASN303 |
D | HIS352 |
D | HIS427 |
D | ZN501 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN D 501 |
Chain | Residue |
D | ENL0 |
D | ASP242 |
D | HIS244 |
D | ASP271 |
D | ZN500 |
site_id | AC6 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE ENL D 0 |
Chain | Residue |
D | ASP242 |
D | HIS244 |
D | ASP271 |
D | ARG275 |
D | ASN303 |
D | HIS304 |
D | ARG400 |
D | HIS427 |
D | GLU428 |
D | VAL429 |
D | PHE446 |
D | TYR451 |
D | ZN500 |
D | ZN501 |
Functional Information from PROSITE/UniProt
site_id | PS00125 |
Number of Residues | 6 |
Details | SER_THR_PHOSPHATASE Serine/threonine specific protein phosphatases signature. LRGNHE |
Chain | Residue | Details |
A | LEU300-GLU305 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS304 | |
D | HIS304 | |
Chain | Residue | Details |
A | ASP242 | |
A | ASP271 | |
A | ASN303 | |
A | HIS352 | |
D | ASP242 | |
D | ASP271 | |
D | ASN303 | |
D | HIS352 | |
Chain | Residue | Details |
A | HIS244 | |
A | ARG275 | |
A | ARG400 | |
A | HIS427 | |
D | HIS244 | |
D | ARG275 | |
D | ARG400 | |
D | HIS427 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1aui |
Chain | Residue | Details |
A | HIS304 | |
A | ASP274 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1aui |
Chain | Residue | Details |
D | HIS304 | |
D | ASP274 | |
site_id | MCSA1 |
Number of Residues | 10 |
Details | M-CSA 472 |
Chain | Residue | Details |
A | ASP242 | metal ligand |
A | HIS427 | activator, metal ligand |
A | HIS244 | metal ligand |
A | ASP271 | metal ligand |
A | ASP274 | activator, proton donor |
A | ARG275 | transition state stabiliser |
A | ASN303 | metal ligand, transition state stabiliser |
A | HIS304 | proton acceptor, proton donor, proton relay |
A | HIS352 | metal ligand |
A | ARG400 | transition state stabiliser |
site_id | MCSA2 |
Number of Residues | 10 |
Details | M-CSA 472 |
Chain | Residue | Details |
D | ASP242 | metal ligand |
D | HIS427 | activator, metal ligand |
D | HIS244 | metal ligand |
D | ASP271 | metal ligand |
D | ASP274 | activator, proton donor |
D | ARG275 | transition state stabiliser |
D | ASN303 | metal ligand, transition state stabiliser |
D | HIS304 | proton acceptor, proton donor, proton relay |
D | HIS352 | metal ligand |
D | ARG400 | transition state stabiliser |