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3H5J

LeuD_1-168 small subunit of isopropylmalate isomerase (Rv2987c) from mycobacterium tuberculosis

Functional Information from GO Data
ChainGOidnamespacecontents
A0003861molecular_function3-isopropylmalate dehydratase activity
A0009098biological_processL-leucine biosynthetic process
A0009316cellular_component3-isopropylmalate dehydratase complex
B0003861molecular_function3-isopropylmalate dehydratase activity
B0009098biological_processL-leucine biosynthetic process
B0009316cellular_component3-isopropylmalate dehydratase complex
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE EDO A 1301
ChainResidue
AGLU2
AHOH505
AGLY106
ALYS107
AGLY109
AARG162
ALEU163
AGLY166
ALEU167
AHOH503

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 1302
ChainResidue
AVAL150
ALEU151
APRO152
AHOH421
AHOH468

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1306
ChainResidue
AARG16
AASP49
AALA51
APHE52
AHOH351
AHOH491

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1307
ChainResidue
APHE29
AARG32
AGLY37
APHE38
AASP40
AGLY41

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 2303
ChainResidue
BSER8
BGLY9
BGLU134
BHOH530
BHOH660

site_idAC6
Number of Residues1
DetailsBINDING SITE FOR RESIDUE EDO B 2304
ChainResidue
BARG15

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO B 2305
ChainResidue
BARG16
BTRP46
BHOH556
BSO42308

site_idAC8
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 B 2308
ChainResidue
BASP49
BALA51
BPHE52
BHOH517
BHOH674
BEDO2305

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup) => ECO:0000269|PubMed:20066036
ChainResidueDetails
APHE153
BPHE153

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PDB entries from 2024-11-06

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