3H45

Glycerol Kinase H232E with Ethylene Glycol

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000166	molecular_function	nucleotide binding
C	0004370	molecular_function	glycerol kinase activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0006071	biological_process	glycerol metabolic process
C	0006072	biological_process	glycerol-3-phosphate metabolic process
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
C	0019563	biological_process	glycerol catabolic process
D	0000166	molecular_function	nucleotide binding
D	0004370	molecular_function	glycerol kinase activity
D	0005524	molecular_function	ATP binding
D	0005829	cellular_component	cytosol
D	0005975	biological_process	carbohydrate metabolic process
D	0006071	biological_process	glycerol metabolic process
D	0006072	biological_process	glycerol-3-phosphate metabolic process
D	0016301	molecular_function	kinase activity
D	0016740	molecular_function	transferase activity
D	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
D	0019563	biological_process	glycerol catabolic process
O	0000166	molecular_function	nucleotide binding
O	0004370	molecular_function	glycerol kinase activity
O	0005524	molecular_function	ATP binding
O	0005829	cellular_component	cytosol
O	0005975	biological_process	carbohydrate metabolic process
O	0006071	biological_process	glycerol metabolic process
O	0006072	biological_process	glycerol-3-phosphate metabolic process
O	0016301	molecular_function	kinase activity
O	0016740	molecular_function	transferase activity
O	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
O	0019563	biological_process	glycerol catabolic process
X	0000166	molecular_function	nucleotide binding
X	0004370	molecular_function	glycerol kinase activity
X	0005524	molecular_function	ATP binding
X	0005829	cellular_component	cytosol
X	0005975	biological_process	carbohydrate metabolic process
X	0006071	biological_process	glycerol metabolic process
X	0006072	biological_process	glycerol-3-phosphate metabolic process
X	0016301	molecular_function	kinase activity
X	0016740	molecular_function	transferase activity
X	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
X	0019563	biological_process	glycerol catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO X 1000

Chain	Residue
X	ARG84
X	GLU85
X	TRP104
X	TYR136
X	ASP246
X	GLN247
X	PHE271
X	HOH531

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO X 507

Chain	Residue
X	HIS126
X	GLU127
O	ASP119

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 X 508

Chain	Residue
X	GLY13
X	THR14
X	GLY267
X	THR268
X	HOH531
X	HOH596

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 X 509

Chain	Residue
O	SER59
O	ALA62
X	SER59
X	GLY63
X	HOH513

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 X 510

Chain	Residue
X	ALA310
X	GLY311
X	ILE314
X	LEU382
X	ALA413
X	LEU419

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO O 1001

Chain	Residue
O	ARG84
O	GLU85
O	TRP104
O	TYR136
O	ASP246
O	GLN247
O	PHE271

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 O 507

Chain	Residue
O	THR14
O	GLY267
O	THR268
O	HOH572

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO C 1002

Chain	Residue
C	ARG84
C	GLU85
C	TYR136
C	ASP246
C	GLN247
C	PHE271

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 C 507

Chain	Residue
C	THR14
C	THR268

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 1003

Chain	Residue
D	ARG84
D	GLU85
D	TYR136
D	ASP246
D	PHE271

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 D 507

Chain	Residue
D	GLY13
D	THR14
D	THR268

---

Functional Information from PROSITE/UniProt

site_id	PS00445
Number of Residues	21
Details	FGGY_KINASES_2 FGGY family of carbohydrate kinases signature 2. GaVFGLtrgttke.DFVRATLQ

Chain	Residue	Details
X	GLY363-GLN383

---

site_id	PS00933
Number of Residues	13
Details	FGGY_KINASES_1 FGGY family of carbohydrate kinases signature 1. YfSatKVRWLLDN

Chain	Residue	Details
X	TYR136-ASN148

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	52
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00186","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00186","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19102629","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3D7E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphohistidine; by HPr","evidences":[{"source":"HAMAP-Rule","id":"MF_00186","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"9162046","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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