Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3H1L

Chicken cytochrome BC1 complex with ascochlorin bound at QO and QI sites

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0046872	molecular_function	metal ion binding
B	0046872	molecular_function	metal ion binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
C	0006979	biological_process	response to oxidative stress
C	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
C	0009055	molecular_function	electron transfer activity
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0020037	molecular_function	heme binding
C	0022904	biological_process	respiratory electron transport chain
C	0045275	cellular_component	respiratory chain complex III
C	0046872	molecular_function	metal ion binding
C	1902600	biological_process	proton transmembrane transport
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0009055	molecular_function	electron transfer activity
D	0020037	molecular_function	heme binding
D	0046872	molecular_function	metal ion binding
E	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
E	0016020	cellular_component	membrane
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F	0045275	cellular_component	respiratory chain complex III
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G	0045275	cellular_component	respiratory chain complex III
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
I	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J	0016020	cellular_component	membrane
J	0045275	cellular_component	respiratory chain complex III
N	0046872	molecular_function	metal ion binding
O	0046872	molecular_function	metal ion binding
P	0005737	cellular_component	cytoplasm
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
P	0006979	biological_process	response to oxidative stress
P	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
P	0009055	molecular_function	electron transfer activity
P	0016020	cellular_component	membrane
P	0016491	molecular_function	oxidoreductase activity
P	0020037	molecular_function	heme binding
P	0022904	biological_process	respiratory electron transport chain
P	0045275	cellular_component	respiratory chain complex III
P	0046872	molecular_function	metal ion binding
P	1902600	biological_process	proton transmembrane transport
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0009055	molecular_function	electron transfer activity
Q	0020037	molecular_function	heme binding
Q	0046872	molecular_function	metal ion binding
R	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
R	0016020	cellular_component	membrane
R	0051537	molecular_function	2 iron, 2 sulfur cluster binding
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
S	0045275	cellular_component	respiratory chain complex III
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
T	0045275	cellular_component	respiratory chain complex III
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
V	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
W	0016020	cellular_component	membrane
W	0045275	cellular_component	respiratory chain complex III

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	54
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000250\|UniProtKB:P13272

Chain	Residue	Details
E	VAL1-SER28
P	TRP78-ILE99
P	TRP114-LEU134
P	PHE179-THR199
P	PHE227-SER247
P	LEU289-HIS309
P	LEU321-SER341
P	PHE348-PRO368
R	VAL1-SER28
C	TRP114-LEU134
C	PHE179-THR199
C	PHE227-SER247
C	LEU289-HIS309
C	LEU321-SER341
C	PHE348-PRO368
P	PHE34-MET54

site_id	SWS_FT_FI2
Number of Residues	66
Details	TRANSMEM: Helical => ECO:0000269\|PubMed:9565029

Chain	Residue	Details
E	SER29-LEU62
R	SER29-LEU62

site_id	SWS_FT_FI3
Number of Residues	266
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000250\|UniProtKB:P13272

Chain	Residue	Details
E	SER63-GLY196
R	SER63-GLY196
P	HIS98
P	HIS197

site_id	SWS_FT_FI4
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269\|PubMed:9565029, ECO:0007744\|PDB:3H1H, ECO:0007744\|PDB:3H1I, ECO:0007744\|PDB:3H1J

Chain	Residue	Details
E	CYS139
R	SER163
E	HIS141
E	CYS158
E	HIS161
E	SER163
R	CYS139
R	HIS141
R	CYS158
R	HIS161

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:9565029, ECO:0007744\|PDB:3H1H, ECO:0007744\|PDB:3H1I

Chain	Residue	Details
E	LEU142
R	LEU142

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1hr6

Chain	Residue	Details
A	GLU60

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1hr6

Chain	Residue	Details
N	GLU60

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1hr6

Chain	Residue	Details
B	ARG70

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1hr6

Chain	Residue	Details
O	ARG70

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)