3H0M

Structure of trna-dependent amidotransferase gatcab from aquifex aeolicus

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Functional Information from GO Data

ChainGOidnamespacecontents
A0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
A0004040molecular_functionamidase activity
A0005524molecular_functionATP binding
A0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
A0006412biological_processtranslation
D0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
D0004040molecular_functionamidase activity
D0005524molecular_functionATP binding
D0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
D0006412biological_processtranslation
G0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
G0004040molecular_functionamidase activity
G0005524molecular_functionATP binding
G0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
G0006412biological_processtranslation
J0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
J0004040molecular_functionamidase activity
J0005524molecular_functionATP binding
J0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
J0006412biological_processtranslation
M0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
M0004040molecular_functionamidase activity
M0005524molecular_functionATP binding
M0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
M0006412biological_processtranslation
P0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
P0004040molecular_functionamidase activity
P0005524molecular_functionATP binding
P0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
P0006412biological_processtranslation
S0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
S0004040molecular_functionamidase activity
S0005524molecular_functionATP binding
S0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
S0006412biological_processtranslation
V0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
V0004040molecular_functionamidase activity
V0005524molecular_functionATP binding
V0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
V0006412biological_processtranslation
B0005739cellular_componentmitochondrion
B0005524molecular_functionATP binding
B0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
B0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
B0032543biological_processmitochondrial translation
E0005739cellular_componentmitochondrion
E0005524molecular_functionATP binding
E0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
E0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
E0032543biological_processmitochondrial translation
H0005739cellular_componentmitochondrion
H0005524molecular_functionATP binding
H0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
H0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
H0032543biological_processmitochondrial translation
K0005739cellular_componentmitochondrion
K0005524molecular_functionATP binding
K0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
K0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
K0032543biological_processmitochondrial translation
N0005739cellular_componentmitochondrion
N0005524molecular_functionATP binding
N0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
N0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
N0032543biological_processmitochondrial translation
Q0005739cellular_componentmitochondrion
Q0005524molecular_functionATP binding
Q0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Q0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
Q0032543biological_processmitochondrial translation
T0005739cellular_componentmitochondrion
T0005524molecular_functionATP binding
T0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
T0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
T0032543biological_processmitochondrial translation
W0005739cellular_componentmitochondrion
W0005524molecular_functionATP binding
W0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
W0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
W0032543biological_processmitochondrial translation
C0005524molecular_functionATP binding
C0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
C0006450biological_processregulation of translational fidelity
C0006412biological_processtranslation
F0005524molecular_functionATP binding
F0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
F0006450biological_processregulation of translational fidelity
F0006412biological_processtranslation
I0005524molecular_functionATP binding
I0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
I0006450biological_processregulation of translational fidelity
I0006412biological_processtranslation
L0005524molecular_functionATP binding
L0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
L0006450biological_processregulation of translational fidelity
L0006412biological_processtranslation
O0005524molecular_functionATP binding
O0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
O0006450biological_processregulation of translational fidelity
O0006412biological_processtranslation
R0005524molecular_functionATP binding
R0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
R0006450biological_processregulation of translational fidelity
R0006412biological_processtranslation
U0005524molecular_functionATP binding
U0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
U0006450biological_processregulation of translational fidelity
U0006412biological_processtranslation
X0005524molecular_functionATP binding
X0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
X0006450biological_processregulation of translational fidelity
X0006412biological_processtranslation
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC114BINDING SITE FOR RESIDUE GLN A 901
ChainResidue
AALA121
AMET122
AGLY123
ASER124
AASP167
ATHR168
AGLY169
AGLY170
ASER171
APHE199
ATYR302
ATYR303
AARG351
AASP418

AC214BINDING SITE FOR RESIDUE GLN D 902
ChainResidue
DALA121
DMET122
DGLY123
DSER124
DASP167
DTHR168
DGLY169
DGLY170
DSER171
DPHE199
DTYR302
DTYR303
DARG351
DASP418

AC314BINDING SITE FOR RESIDUE GLN G 903
ChainResidue
GALA121
GMET122
GGLY123
GSER124
GSER147
GSER166
GASP167
GTHR168
GGLY169
GSER171
GPHE199
GTYR302
GARG351
GASP418

AC413BINDING SITE FOR RESIDUE GLN J 904
ChainResidue
JALA121
JMET122
JGLY123
JASP167
JTHR168
JGLY169
JGLY170
JSER171
JPHE199
JTYR302
JTYR303
JARG351
JASP418

AC512BINDING SITE FOR RESIDUE GLN M 905
ChainResidue
MMET122
MGLY123
MSER124
MASP167
MTHR168
MGLY169
MGLY170
MSER171
MPHE199
MTYR302
MARG351
MASP418

AC613BINDING SITE FOR RESIDUE GLN P 906
ChainResidue
PMET122
PGLY123
PSER124
PASP167
PTHR168
PGLY169
PGLY170
PSER171
PPHE199
PTYR302
PTYR303
PARG351
PASP418

AC713BINDING SITE FOR RESIDUE GLN S 907
ChainResidue
SALA121
SMET122
SGLY123
SSER124
SSER147
SASP167
STHR168
SGLY169
SSER171
STYR302
STYR303
SARG351
SASP418

AC813BINDING SITE FOR RESIDUE GLN V 908
ChainResidue
VMET122
VGLY123
VSER124
VASP167
VTHR168
VGLY169
VGLY170
VSER171
VPHE199
VTYR302
VTYR303
VARG351
VASP418

AC93BINDING SITE FOR RESIDUE MG B 479
ChainResidue
BHIS14
BGLU127
BGLU153

BC13BINDING SITE FOR RESIDUE MG H 479
ChainResidue
HHIS14
HGLU127
HGLU153

BC23BINDING SITE FOR RESIDUE MG K 479
ChainResidue
KHIS14
KGLU127
KGLU153

BC33BINDING SITE FOR RESIDUE MG N 479
ChainResidue
NHIS14
NGLU127
NGLU153

BC43BINDING SITE FOR RESIDUE MG Q 479
ChainResidue
QHIS14
QGLU127
QGLU153

BC53BINDING SITE FOR RESIDUE MG T 479
ChainResidue
THIS14
TGLU127
TGLU153

BC63BINDING SITE FOR RESIDUE MG W 479
ChainResidue
WHIS14
WGLU127
WGLU153

BC74BINDING SITE FOR RESIDUE ZN B 901
ChainResidue
BCYS25
BCYS27
BCYS40
BCYS43

BC84BINDING SITE FOR RESIDUE ZN E 902
ChainResidue
ECYS25
ECYS27
ECYS40
ECYS43

BC94BINDING SITE FOR RESIDUE ZN H 903
ChainResidue
HCYS25
HCYS27
HCYS40
HCYS43

CC14BINDING SITE FOR RESIDUE ZN K 904
ChainResidue
KCYS25
KCYS27
KCYS40
KCYS43

CC24BINDING SITE FOR RESIDUE ZN N 905
ChainResidue
NCYS25
NCYS27
NCYS40
NCYS43

CC34BINDING SITE FOR RESIDUE ZN Q 906
ChainResidue
QCYS25
QCYS27
QCYS40
QCYS43

CC44BINDING SITE FOR RESIDUE ZN T 907
ChainResidue
TCYS25
TCYS27
TCYS40
TCYS43

CC54BINDING SITE FOR RESIDUE ZN W 908
ChainResidue
WCYS25
WCYS27
WCYS40
WCYS43

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
GLN_3h0m_A_90118GLUTAMINE binding site
ChainResidueligand
AALA121-SER124GLN: GLUTAMINE
AGLY146-SER147GLN: GLUTAMINE
ASER166-ILE172GLN: GLUTAMINE
APHE199GLN: GLUTAMINE
ATYR302-TYR303GLN: GLUTAMINE
AARG351GLN: GLUTAMINE
AASP418GLN: GLUTAMINE

GLN_3h0m_D_90218GLUTAMINE binding site
ChainResidueligand
DALA121-SER124GLN: GLUTAMINE
DGLY146-SER147GLN: GLUTAMINE
DSER166-ILE172GLN: GLUTAMINE
DPHE199GLN: GLUTAMINE
DTYR302-TYR303GLN: GLUTAMINE
DARG351GLN: GLUTAMINE
DASP418GLN: GLUTAMINE

GLN_3h0m_G_90319GLUTAMINE binding site
ChainResidueligand
GLYS72GLN: GLUTAMINE
GALA121-SER124GLN: GLUTAMINE
GGLY146-SER147GLN: GLUTAMINE
GSER166-ILE172GLN: GLUTAMINE
GPHE199GLN: GLUTAMINE
GTYR302-TYR303GLN: GLUTAMINE
GARG351GLN: GLUTAMINE
GASP418GLN: GLUTAMINE

GLN_3h0m_J_90416GLUTAMINE binding site
ChainResidueligand
JALA121-SER124GLN: GLUTAMINE
JSER147GLN: GLUTAMINE
JSER166-SER171GLN: GLUTAMINE
JPHE199GLN: GLUTAMINE
JTYR302-TYR303GLN: GLUTAMINE
JARG351GLN: GLUTAMINE
JASP418GLN: GLUTAMINE

GLN_3h0m_M_90518GLUTAMINE binding site
ChainResidueligand
MALA121-SER124GLN: GLUTAMINE
MGLY146-SER147GLN: GLUTAMINE
MSER166-ILE172GLN: GLUTAMINE
MPHE199GLN: GLUTAMINE
MTYR302-TYR303GLN: GLUTAMINE
MARG351GLN: GLUTAMINE
MASP418GLN: GLUTAMINE

GLN_3h0m_P_90618GLUTAMINE binding site
ChainResidueligand
PALA121-SER124GLN: GLUTAMINE
PSER147GLN: GLUTAMINE
PSER166-ILE172GLN: GLUTAMINE
PPHE199GLN: GLUTAMINE
PTYR302-TYR303GLN: GLUTAMINE
PARG351GLN: GLUTAMINE
PASP418GLN: GLUTAMINE
PASN425GLN: GLUTAMINE

GLN_3h0m_S_90719GLUTAMINE binding site
ChainResidueligand
SLYS72GLN: GLUTAMINE
SALA121-SER124GLN: GLUTAMINE
SGLY146-SER147GLN: GLUTAMINE
SSER166-SER171GLN: GLUTAMINE
SPHE199GLN: GLUTAMINE
STYR302-TYR303GLN: GLUTAMINE
SARG351GLN: GLUTAMINE
SASP418GLN: GLUTAMINE
SVAL422GLN: GLUTAMINE

GLN_3h0m_V_90818GLUTAMINE binding site
ChainResidueligand
VALA121-SER124GLN: GLUTAMINE
VGLY146-SER147GLN: GLUTAMINE
VSER166-ILE172GLN: GLUTAMINE
VPHE199GLN: GLUTAMINE
VTYR302-TYR303GLN: GLUTAMINE
VARG351GLN: GLUTAMINE
VASP418GLN: GLUTAMINE

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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI12Charge relay system (By similarity).
ChainResidueDetails
ALYS72
ASER147

SWS_FT_FI21Acyl-ester intermediate (By similarity).
ChainResidueDetails
ASER171

SWS_FT_FI32Charge relay system (By similarity).
ChainResidueDetails
DLYS72
DSER147

SWS_FT_FI41Acyl-ester intermediate (By similarity).
ChainResidueDetails
DSER171

SWS_FT_FI52Charge relay system (By similarity).
ChainResidueDetails
GLYS72
GSER147

SWS_FT_FI61Acyl-ester intermediate (By similarity).
ChainResidueDetails
GSER171

SWS_FT_FI72Charge relay system (By similarity).
ChainResidueDetails
JLYS72
JSER147

SWS_FT_FI81Acyl-ester intermediate (By similarity).
ChainResidueDetails
JSER171

SWS_FT_FI92Charge relay system (By similarity).
ChainResidueDetails
MLYS72
MSER147

SWS_FT_FI101Acyl-ester intermediate (By similarity).
ChainResidueDetails
MSER171

SWS_FT_FI112Charge relay system (By similarity).
ChainResidueDetails
PLYS72
PSER147

SWS_FT_FI121Acyl-ester intermediate (By similarity).
ChainResidueDetails
PSER171

SWS_FT_FI132Charge relay system (By similarity).
ChainResidueDetails
SLYS72
SSER147

SWS_FT_FI141Acyl-ester intermediate (By similarity).
ChainResidueDetails
SSER171

SWS_FT_FI152Charge relay system (By similarity).
ChainResidueDetails
VLYS72
VSER147

SWS_FT_FI161Acyl-ester intermediate (By similarity).
ChainResidueDetails
VSER171

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Catalytic Information from CSA

site_idNumber of ResiduesDetails