3H0L

Structure of trna-dependent amidotransferase gatcab from aquifex aeolicus

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Functional Information from GO Data

ChainGOidnamespacecontents
A0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
A0004040molecular_functionamidase activity
A0005524molecular_functionATP binding
A0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
A0006412biological_processtranslation
D0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
D0004040molecular_functionamidase activity
D0005524molecular_functionATP binding
D0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
D0006412biological_processtranslation
G0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
G0004040molecular_functionamidase activity
G0005524molecular_functionATP binding
G0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
G0006412biological_processtranslation
J0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
J0004040molecular_functionamidase activity
J0005524molecular_functionATP binding
J0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
J0006412biological_processtranslation
M0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
M0004040molecular_functionamidase activity
M0005524molecular_functionATP binding
M0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
M0006412biological_processtranslation
P0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
P0004040molecular_functionamidase activity
P0005524molecular_functionATP binding
P0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
P0006412biological_processtranslation
S0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
S0004040molecular_functionamidase activity
S0005524molecular_functionATP binding
S0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
S0006412biological_processtranslation
V0030956cellular_componentglutamyl-tRNA(Gln) amidotransferase complex
V0004040molecular_functionamidase activity
V0005524molecular_functionATP binding
V0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
V0006412biological_processtranslation
B0005739cellular_componentmitochondrion
B0005524molecular_functionATP binding
B0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
B0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
B0032543biological_processmitochondrial translation
E0005739cellular_componentmitochondrion
E0005524molecular_functionATP binding
E0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
E0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
E0032543biological_processmitochondrial translation
H0005739cellular_componentmitochondrion
H0005524molecular_functionATP binding
H0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
H0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
H0032543biological_processmitochondrial translation
K0005739cellular_componentmitochondrion
K0005524molecular_functionATP binding
K0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
K0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
K0032543biological_processmitochondrial translation
N0005739cellular_componentmitochondrion
N0005524molecular_functionATP binding
N0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
N0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
N0032543biological_processmitochondrial translation
Q0005739cellular_componentmitochondrion
Q0005524molecular_functionATP binding
Q0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Q0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
Q0032543biological_processmitochondrial translation
T0005739cellular_componentmitochondrion
T0005524molecular_functionATP binding
T0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
T0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
T0032543biological_processmitochondrial translation
W0005739cellular_componentmitochondrion
W0005524molecular_functionATP binding
W0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
W0070681biological_processglutaminyl-tRNAGln biosynthesis via transamidation
W0032543biological_processmitochondrial translation
C0005524molecular_functionATP binding
C0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
C0006450biological_processregulation of translational fidelity
C0006412biological_processtranslation
F0005524molecular_functionATP binding
F0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
F0006450biological_processregulation of translational fidelity
F0006412biological_processtranslation
I0005524molecular_functionATP binding
I0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
I0006450biological_processregulation of translational fidelity
I0006412biological_processtranslation
L0005524molecular_functionATP binding
L0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
L0006450biological_processregulation of translational fidelity
L0006412biological_processtranslation
O0005524molecular_functionATP binding
O0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
O0006450biological_processregulation of translational fidelity
O0006412biological_processtranslation
R0005524molecular_functionATP binding
R0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
R0006450biological_processregulation of translational fidelity
R0006412biological_processtranslation
U0005524molecular_functionATP binding
U0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
U0006450biological_processregulation of translational fidelity
U0006412biological_processtranslation
X0005524molecular_functionATP binding
X0050567molecular_functionglutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
X0006450biological_processregulation of translational fidelity
X0006412biological_processtranslation
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC112BINDING SITE FOR RESIDUE ADP B 701
ChainResidue
BVAL8
BGLY10
BLEU11
BGLU12
BVAL155
BTHR156
BGLU157
BPRO158
BASN197
BSER199
BGLY209
BARG211

AC23BINDING SITE FOR RESIDUE MG B 801
ChainResidue
BHIS14
BGLU127
BGLU153

AC34BINDING SITE FOR RESIDUE ZN B 901
ChainResidue
BCYS25
BCYS27
BCYS40
BCYS43

AC412BINDING SITE FOR RESIDUE ADP E 702
ChainResidue
EVAL8
EGLY10
ELEU11
EGLU12
EVAL155
ETHR156
EGLU157
EPRO158
EASN197
ESER199
EGLY209
EARG211

AC53BINDING SITE FOR RESIDUE MG E 802
ChainResidue
EHIS14
EGLU127
EGLU153

AC64BINDING SITE FOR RESIDUE ZN E 902
ChainResidue
ECYS25
ECYS27
ECYS40
ECYS43

AC712BINDING SITE FOR RESIDUE ADP H 703
ChainResidue
HVAL8
HGLY10
HLEU11
HGLU12
HVAL155
HTHR156
HGLU157
HPRO158
HASN197
HSER199
HGLY209
HARG211

AC83BINDING SITE FOR RESIDUE MG H 803
ChainResidue
HHIS14
HGLU127
HGLU153

AC94BINDING SITE FOR RESIDUE ZN H 903
ChainResidue
HCYS25
HCYS27
HCYS40
HCYS43

BC112BINDING SITE FOR RESIDUE ADP K 704
ChainResidue
KVAL8
KGLY10
KLEU11
KGLU12
KVAL155
KTHR156
KGLU157
KPRO158
KASN197
KSER199
KGLY209
KARG211

BC23BINDING SITE FOR RESIDUE MG K 804
ChainResidue
KHIS14
KGLU127
KGLU153

BC34BINDING SITE FOR RESIDUE ZN K 904
ChainResidue
KCYS25
KCYS27
KCYS40
KCYS43

BC412BINDING SITE FOR RESIDUE ADP N 705
ChainResidue
NVAL8
NGLY10
NLEU11
NGLU12
NVAL155
NTHR156
NGLU157
NPRO158
NASN197
NSER199
NGLY209
NARG211

BC53BINDING SITE FOR RESIDUE MG N 805
ChainResidue
NHIS14
NGLU127
NGLU153

BC64BINDING SITE FOR RESIDUE ZN N 905
ChainResidue
NCYS25
NCYS27
NCYS40
NCYS43

BC713BINDING SITE FOR RESIDUE ADP Q 706
ChainResidue
QVAL8
QGLY10
QLEU11
QGLU12
QVAL155
QTHR156
QGLU157
QPRO158
QASN197
QVAL198
QSER199
QGLY209
QARG211

BC83BINDING SITE FOR RESIDUE MG Q 806
ChainResidue
QHIS14
QGLU127
QGLU153

BC94BINDING SITE FOR RESIDUE ZN Q 906
ChainResidue
QCYS25
QCYS27
QCYS40
QCYS43

CC112BINDING SITE FOR RESIDUE ADP T 707
ChainResidue
TVAL8
TGLY10
TLEU11
TGLU12
TVAL155
TTHR156
TGLU157
TPRO158
TASN197
TSER199
TGLY209
TARG211

CC23BINDING SITE FOR RESIDUE MG T 807
ChainResidue
THIS14
TGLU127
TGLU153

CC34BINDING SITE FOR RESIDUE ZN T 907
ChainResidue
TCYS25
TCYS27
TCYS40
TCYS43

CC412BINDING SITE FOR RESIDUE ADP W 708
ChainResidue
WVAL8
WGLY10
WLEU11
WGLU12
WVAL155
WTHR156
WGLU157
WPRO158
WASN197
WSER199
WGLY209
WARG211

CC53BINDING SITE FOR RESIDUE MG W 808
ChainResidue
WHIS14
WGLU127
WGLU153

CC64BINDING SITE FOR RESIDUE ZN W 908
ChainResidue
WCYS25
WCYS27
WCYS40
WCYS43

CC711BINDING SITE FOR RESIDUE ASN A 901
ChainResidue
AALA121
AGLY123
ASER124
ASER147
AGLY169
AGLY170
ASER171
ATYR302
ATYR303
AARG351
AASP418

CC811BINDING SITE FOR RESIDUE ASN D 902
ChainResidue
DALA121
DMET122
DGLY123
DSER124
DGLY169
DGLY170
DSER171
DPHE199
DTYR302
DARG351
DASP418

CC911BINDING SITE FOR RESIDUE ASN G 903
ChainResidue
GALA121
GGLY123
GSER124
GTHR168
GGLY169
GGLY170
GSER171
GPHE199
GTYR302
GARG351
GASP418

DC112BINDING SITE FOR RESIDUE ASN J 904
ChainResidue
JALA121
JMET122
JGLY123
JSER124
JTHR168
JGLY169
JGLY170
JSER171
JPHE199
JTYR302
JARG351
JASP418

DC211BINDING SITE FOR RESIDUE ASN M 905
ChainResidue
MALA121
MMET122
MGLY123
MSER124
MGLY169
MGLY170
MSER171
MTYR302
MTYR303
MARG351
MASP418

DC313BINDING SITE FOR RESIDUE ASN P 906
ChainResidue
PALA121
PMET122
PGLY123
PSER124
PSER147
PTHR168
PGLY169
PGLY170
PSER171
PPHE199
PTYR302
PARG351
PASP418

DC412BINDING SITE FOR RESIDUE ASN S 907
ChainResidue
SALA121
SMET122
SGLY123
SSER124
STHR168
SGLY169
SGLY170
SSER171
SPHE199
STYR302
SARG351
SASP418

DC59BINDING SITE FOR RESIDUE ASN V 908
ChainResidue
VALA121
VGLY123
VGLY169
VGLY170
VSER171
VPHE199
VTYR302
VARG351
VASP418

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
ASN_3h0l_A_90116ASPARAGINE binding site
ChainResidueligand
AALA121-SER124ASN: ASPARAGINE
AGLY146-SER147ASN: ASPARAGINE
AASP167-SER171ASN: ASPARAGINE
APHE199ASN: ASPARAGINE
ATYR302-TYR303ASN: ASPARAGINE
AARG351ASN: ASPARAGINE
AASP418ASN: ASPARAGINE

ADP_3h0l_B_70116ADENOSINE-5'-DIPHOSPHATE binding site
ChainResidueligand
BVAL8-GLU12ADP: ADENOSINE-5'-DIPHOSPHATE
BARG122ADP: ADENOSINE-5'-DIPHOSPHATE
BVAL155-PRO158ADP: ADENOSINE-5'-DIPHOSPHATE
BASN197-SER199ADP: ADENOSINE-5'-DIPHOSPHATE
BPHE208-GLY209ADP: ADENOSINE-5'-DIPHOSPHATE
BARG211ADP: ADENOSINE-5'-DIPHOSPHATE

ASN_3h0l_D_90216ASPARAGINE binding site
ChainResidueligand
DALA121-SER124ASN: ASPARAGINE
DGLY146-SER147ASN: ASPARAGINE
DASP167-SER171ASN: ASPARAGINE
DPHE199ASN: ASPARAGINE
DTYR302-TYR303ASN: ASPARAGINE
DARG351ASN: ASPARAGINE
DASP418ASN: ASPARAGINE

ADP_3h0l_E_70217ADENOSINE-5'-DIPHOSPHATE binding site
ChainResidueligand
EVAL8-GLU12ADP: ADENOSINE-5'-DIPHOSPHATE
EARG122-ARG123ADP: ADENOSINE-5'-DIPHOSPHATE
EVAL155-PRO158ADP: ADENOSINE-5'-DIPHOSPHATE
EASN197-SER199ADP: ADENOSINE-5'-DIPHOSPHATE
EPHE208-GLY209ADP: ADENOSINE-5'-DIPHOSPHATE
EARG211ADP: ADENOSINE-5'-DIPHOSPHATE

ASN_3h0l_G_90316ASPARAGINE binding site
ChainResidueligand
GALA121-SER124ASN: ASPARAGINE
GGLY146-SER147ASN: ASPARAGINE
GASP167-SER171ASN: ASPARAGINE
GPHE199ASN: ASPARAGINE
GTYR302-TYR303ASN: ASPARAGINE
GARG351ASN: ASPARAGINE
GASP418ASN: ASPARAGINE

ADP_3h0l_H_70316ADENOSINE-5'-DIPHOSPHATE binding site
ChainResidueligand
HVAL8-GLU12ADP: ADENOSINE-5'-DIPHOSPHATE
HARG122ADP: ADENOSINE-5'-DIPHOSPHATE
HVAL155-PRO158ADP: ADENOSINE-5'-DIPHOSPHATE
HASN197-SER199ADP: ADENOSINE-5'-DIPHOSPHATE
HPHE208-GLY209ADP: ADENOSINE-5'-DIPHOSPHATE
HARG211ADP: ADENOSINE-5'-DIPHOSPHATE

ASN_3h0l_J_90416ASPARAGINE binding site
ChainResidueligand
JALA121-SER124ASN: ASPARAGINE
JGLY146-SER147ASN: ASPARAGINE
JASP167-SER171ASN: ASPARAGINE
JPHE199ASN: ASPARAGINE
JTYR302-TYR303ASN: ASPARAGINE
JARG351ASN: ASPARAGINE
JASP418ASN: ASPARAGINE

ADP_3h0l_K_70416ADENOSINE-5'-DIPHOSPHATE binding site
ChainResidueligand
KVAL8-GLU12ADP: ADENOSINE-5'-DIPHOSPHATE
KARG122ADP: ADENOSINE-5'-DIPHOSPHATE
KVAL155-PRO158ADP: ADENOSINE-5'-DIPHOSPHATE
KASN197-SER199ADP: ADENOSINE-5'-DIPHOSPHATE
KPHE208-GLY209ADP: ADENOSINE-5'-DIPHOSPHATE
KARG211ADP: ADENOSINE-5'-DIPHOSPHATE

ASN_3h0l_M_90516ASPARAGINE binding site
ChainResidueligand
MALA121-SER124ASN: ASPARAGINE
MGLY146-SER147ASN: ASPARAGINE
MASP167-SER171ASN: ASPARAGINE
MPHE199ASN: ASPARAGINE
MTYR302-TYR303ASN: ASPARAGINE
MARG351ASN: ASPARAGINE
MASP418ASN: ASPARAGINE

ADP_3h0l_N_70516ADENOSINE-5'-DIPHOSPHATE binding site
ChainResidueligand
NVAL8-GLU12ADP: ADENOSINE-5'-DIPHOSPHATE
NARG122ADP: ADENOSINE-5'-DIPHOSPHATE
NVAL155-PRO158ADP: ADENOSINE-5'-DIPHOSPHATE
NASN197-SER199ADP: ADENOSINE-5'-DIPHOSPHATE
NPHE208-GLY209ADP: ADENOSINE-5'-DIPHOSPHATE
NARG211ADP: ADENOSINE-5'-DIPHOSPHATE

ASN_3h0l_P_90616ASPARAGINE binding site
ChainResidueligand
PALA121-SER124ASN: ASPARAGINE
PGLY146-SER147ASN: ASPARAGINE
PASP167-SER171ASN: ASPARAGINE
PPHE199ASN: ASPARAGINE
PTYR302-TYR303ASN: ASPARAGINE
PARG351ASN: ASPARAGINE
PASP418ASN: ASPARAGINE

ADP_3h0l_Q_70616ADENOSINE-5'-DIPHOSPHATE binding site
ChainResidueligand
QVAL8-GLU12ADP: ADENOSINE-5'-DIPHOSPHATE
QARG122ADP: ADENOSINE-5'-DIPHOSPHATE
QVAL155-PRO158ADP: ADENOSINE-5'-DIPHOSPHATE
QASN197-SER199ADP: ADENOSINE-5'-DIPHOSPHATE
QPHE208-GLY209ADP: ADENOSINE-5'-DIPHOSPHATE
QARG211ADP: ADENOSINE-5'-DIPHOSPHATE

ASN_3h0l_S_90716ASPARAGINE binding site
ChainResidueligand
SALA121-SER124ASN: ASPARAGINE
SGLY146-SER147ASN: ASPARAGINE
SASP167-SER171ASN: ASPARAGINE
SPHE199ASN: ASPARAGINE
STYR302-TYR303ASN: ASPARAGINE
SARG351ASN: ASPARAGINE
SASP418ASN: ASPARAGINE

ADP_3h0l_T_70715ADENOSINE-5'-DIPHOSPHATE binding site
ChainResidueligand
TVAL8-GLU12ADP: ADENOSINE-5'-DIPHOSPHATE
TVAL155-PRO158ADP: ADENOSINE-5'-DIPHOSPHATE
TASN197-SER199ADP: ADENOSINE-5'-DIPHOSPHATE
TPHE208-GLY209ADP: ADENOSINE-5'-DIPHOSPHATE
TARG211ADP: ADENOSINE-5'-DIPHOSPHATE

ASN_3h0l_V_90816ASPARAGINE binding site
ChainResidueligand
VALA121-SER124ASN: ASPARAGINE
VGLY146-SER147ASN: ASPARAGINE
VASP167-SER171ASN: ASPARAGINE
VPHE199ASN: ASPARAGINE
VTYR302-TYR303ASN: ASPARAGINE
VARG351ASN: ASPARAGINE
VASP418ASN: ASPARAGINE

ADP_3h0l_W_70817ADENOSINE-5'-DIPHOSPHATE binding site
ChainResidueligand
WVAL8-GLU12ADP: ADENOSINE-5'-DIPHOSPHATE
WARG122ADP: ADENOSINE-5'-DIPHOSPHATE
WVAL155-PRO158ADP: ADENOSINE-5'-DIPHOSPHATE
WASN197-SER199ADP: ADENOSINE-5'-DIPHOSPHATE
WPHE208-ARG211ADP: ADENOSINE-5'-DIPHOSPHATE

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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI12Charge relay system (By similarity).
ChainResidueDetails
ALYS72
ASER147

SWS_FT_FI21Acyl-ester intermediate (By similarity).
ChainResidueDetails
ASER171

SWS_FT_FI32Charge relay system (By similarity).
ChainResidueDetails
DLYS72
DSER147

SWS_FT_FI41Acyl-ester intermediate (By similarity).
ChainResidueDetails
DSER171

SWS_FT_FI52Charge relay system (By similarity).
ChainResidueDetails
GLYS72
GSER147

SWS_FT_FI61Acyl-ester intermediate (By similarity).
ChainResidueDetails
GSER171

SWS_FT_FI72Charge relay system (By similarity).
ChainResidueDetails
JLYS72
JSER147

SWS_FT_FI81Acyl-ester intermediate (By similarity).
ChainResidueDetails
JSER171

SWS_FT_FI92Charge relay system (By similarity).
ChainResidueDetails
MLYS72
MSER147

SWS_FT_FI101Acyl-ester intermediate (By similarity).
ChainResidueDetails
MSER171

SWS_FT_FI112Charge relay system (By similarity).
ChainResidueDetails
PLYS72
PSER147

SWS_FT_FI121Acyl-ester intermediate (By similarity).
ChainResidueDetails
PSER171

SWS_FT_FI132Charge relay system (By similarity).
ChainResidueDetails
SLYS72
SSER147

SWS_FT_FI141Acyl-ester intermediate (By similarity).
ChainResidueDetails
SSER171

SWS_FT_FI152Charge relay system (By similarity).
ChainResidueDetails
VLYS72
VSER147

SWS_FT_FI161Acyl-ester intermediate (By similarity).
ChainResidueDetails
VSER171

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Catalytic Information from CSA

site_idNumber of ResiduesDetails