3H0G

RNA Polymerase II from Schizosaccharomyces pombe

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0000785	cellular_component	chromatin
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed RNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005665	cellular_component	RNA polymerase II, core complex
A	0006325	biological_process	chromatin organization
A	0006351	biological_process	DNA-templated transcription
A	0006366	biological_process	transcription by RNA polymerase II
A	0006367	biological_process	transcription initiation at RNA polymerase II promoter
A	0006368	biological_process	transcription elongation by RNA polymerase II
A	0006369	biological_process	termination of RNA polymerase II transcription
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0016591	cellular_component	RNA polymerase II, holoenzyme
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0030643	biological_process	intracellular phosphate ion homeostasis
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0042789	biological_process	mRNA transcription by RNA polymerase II
A	0046872	molecular_function	metal ion binding
A	0140463	molecular_function	chromatin-protein adaptor activity
A	0180034	biological_process	co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003723	molecular_function	RNA binding
B	0003899	molecular_function	DNA-directed RNA polymerase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005665	cellular_component	RNA polymerase II, core complex
B	0005721	cellular_component	pericentric heterochromatin
B	0005829	cellular_component	cytosol
B	0006351	biological_process	DNA-templated transcription
B	0006366	biological_process	transcription by RNA polymerase II
B	0006367	biological_process	transcription initiation at RNA polymerase II promoter
B	0008270	molecular_function	zinc ion binding
B	0016591	cellular_component	RNA polymerase II, holoenzyme
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0031047	biological_process	regulatory ncRNA-mediated gene silencing
B	0032549	molecular_function	ribonucleoside binding
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0046872	molecular_function	metal ion binding
B	0140727	biological_process	siRNA-mediated pericentric heterochromatin formation
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0000785	cellular_component	chromatin
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed RNA polymerase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005665	cellular_component	RNA polymerase II, core complex
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006366	biological_process	transcription by RNA polymerase II
C	0016591	cellular_component	RNA polymerase II, holoenzyme
C	0046983	molecular_function	protein dimerization activity
C	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
D	0000166	molecular_function	nucleotide binding
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0003899	molecular_function	DNA-directed RNA polymerase activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005665	cellular_component	RNA polymerase II, core complex
D	0006352	biological_process	DNA-templated transcription initiation
D	0006366	biological_process	transcription by RNA polymerase II
D	0006367	biological_process	transcription initiation at RNA polymerase II promoter
D	0016591	cellular_component	RNA polymerase II, holoenzyme
D	0030880	cellular_component	RNA polymerase complex
D	0031369	molecular_function	translation initiation factor binding
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed RNA polymerase activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005665	cellular_component	RNA polymerase II, core complex
E	0005666	cellular_component	RNA polymerase III complex
E	0005736	cellular_component	RNA polymerase I complex
E	0005829	cellular_component	cytosol
E	0006351	biological_process	DNA-templated transcription
E	0006360	biological_process	transcription by RNA polymerase I
E	0006362	biological_process	transcription elongation by RNA polymerase I
E	0006366	biological_process	transcription by RNA polymerase II
E	0006367	biological_process	transcription initiation at RNA polymerase II promoter
E	0006383	biological_process	transcription by RNA polymerase III
E	0016591	cellular_component	RNA polymerase II, holoenzyme
E	0042797	biological_process	tRNA transcription by RNA polymerase III
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0003677	molecular_function	DNA binding
F	0003899	molecular_function	DNA-directed RNA polymerase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005665	cellular_component	RNA polymerase II, core complex
F	0005666	cellular_component	RNA polymerase III complex
F	0005736	cellular_component	RNA polymerase I complex
F	0005829	cellular_component	cytosol
F	0006351	biological_process	DNA-templated transcription
F	0006354	biological_process	DNA-templated transcription elongation
F	0006360	biological_process	transcription by RNA polymerase I
F	0006362	biological_process	transcription elongation by RNA polymerase I
F	0006366	biological_process	transcription by RNA polymerase II
F	0016591	cellular_component	RNA polymerase II, holoenzyme
F	0042797	biological_process	tRNA transcription by RNA polymerase III
G	0000428	cellular_component	DNA-directed RNA polymerase complex
G	0000932	cellular_component	P-body
G	0000956	biological_process	nuclear-transcribed mRNA catabolic process
G	0003676	molecular_function	nucleic acid binding
G	0003697	molecular_function	single-stranded DNA binding
G	0003727	molecular_function	single-stranded RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005665	cellular_component	RNA polymerase II, core complex
G	0005829	cellular_component	cytosol
G	0006351	biological_process	DNA-templated transcription
G	0006352	biological_process	DNA-templated transcription initiation
G	0006367	biological_process	transcription initiation at RNA polymerase II promoter
G	0010590	biological_process	regulation of septum digestion after cytokinesis
G	0016591	cellular_component	RNA polymerase II, holoenzyme
G	0031369	molecular_function	translation initiation factor binding
G	0045948	biological_process	positive regulation of translational initiation
G	0060213	biological_process	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
H	0000428	cellular_component	DNA-directed RNA polymerase complex
H	0003677	molecular_function	DNA binding
H	0003899	molecular_function	DNA-directed RNA polymerase activity
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005665	cellular_component	RNA polymerase II, core complex
H	0005666	cellular_component	RNA polymerase III complex
H	0005736	cellular_component	RNA polymerase I complex
H	0005829	cellular_component	cytosol
H	0006351	biological_process	DNA-templated transcription
H	0006362	biological_process	transcription elongation by RNA polymerase I
H	0006366	biological_process	transcription by RNA polymerase II
H	0006383	biological_process	transcription by RNA polymerase III
H	0016591	cellular_component	RNA polymerase II, holoenzyme
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0001193	biological_process	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I	0003676	molecular_function	nucleic acid binding
I	0003899	molecular_function	DNA-directed RNA polymerase activity
I	0005634	cellular_component	nucleus
I	0005665	cellular_component	RNA polymerase II, core complex
I	0005730	cellular_component	nucleolus
I	0005829	cellular_component	cytosol
I	0006283	biological_process	transcription-coupled nucleotide-excision repair
I	0006351	biological_process	DNA-templated transcription
I	0006367	biological_process	transcription initiation at RNA polymerase II promoter
I	0008270	molecular_function	zinc ion binding
I	0016591	cellular_component	RNA polymerase II, holoenzyme
I	0046872	molecular_function	metal ion binding
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0003677	molecular_function	DNA binding
J	0003899	molecular_function	DNA-directed RNA polymerase activity
J	0005634	cellular_component	nucleus
J	0005665	cellular_component	RNA polymerase II, core complex
J	0005666	cellular_component	RNA polymerase III complex
J	0005730	cellular_component	nucleolus
J	0005736	cellular_component	RNA polymerase I complex
J	0005829	cellular_component	cytosol
J	0006351	biological_process	DNA-templated transcription
J	0006360	biological_process	transcription by RNA polymerase I
J	0006362	biological_process	transcription elongation by RNA polymerase I
J	0006366	biological_process	transcription by RNA polymerase II
J	0006367	biological_process	transcription initiation at RNA polymerase II promoter
J	0006383	biological_process	transcription by RNA polymerase III
J	0008270	molecular_function	zinc ion binding
J	0016591	cellular_component	RNA polymerase II, holoenzyme
J	0042797	biological_process	tRNA transcription by RNA polymerase III
J	0046872	molecular_function	metal ion binding
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed RNA polymerase activity
K	0005634	cellular_component	nucleus
K	0005665	cellular_component	RNA polymerase II, core complex
K	0005829	cellular_component	cytosol
K	0006351	biological_process	DNA-templated transcription
K	0006366	biological_process	transcription by RNA polymerase II
K	0006367	biological_process	transcription initiation at RNA polymerase II promoter
K	0016591	cellular_component	RNA polymerase II, holoenzyme
K	0046983	molecular_function	protein dimerization activity
L	0000428	cellular_component	DNA-directed RNA polymerase complex
L	0003677	molecular_function	DNA binding
L	0003899	molecular_function	DNA-directed RNA polymerase activity
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005665	cellular_component	RNA polymerase II, core complex
L	0005666	cellular_component	RNA polymerase III complex
L	0005730	cellular_component	nucleolus
L	0005736	cellular_component	RNA polymerase I complex
L	0005829	cellular_component	cytosol
L	0006351	biological_process	DNA-templated transcription
L	0006360	biological_process	transcription by RNA polymerase I
L	0006362	biological_process	transcription elongation by RNA polymerase I
L	0006366	biological_process	transcription by RNA polymerase II
L	0006383	biological_process	transcription by RNA polymerase III
L	0008270	molecular_function	zinc ion binding
L	0046872	molecular_function	metal ion binding
M	0000428	cellular_component	DNA-directed RNA polymerase complex
M	0000785	cellular_component	chromatin
M	0003677	molecular_function	DNA binding
M	0003899	molecular_function	DNA-directed RNA polymerase activity
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005665	cellular_component	RNA polymerase II, core complex
M	0006325	biological_process	chromatin organization
M	0006351	biological_process	DNA-templated transcription
M	0006366	biological_process	transcription by RNA polymerase II
M	0006367	biological_process	transcription initiation at RNA polymerase II promoter
M	0006368	biological_process	transcription elongation by RNA polymerase II
M	0006369	biological_process	termination of RNA polymerase II transcription
M	0006370	biological_process	7-methylguanosine mRNA capping
M	0016591	cellular_component	RNA polymerase II, holoenzyme
M	0016740	molecular_function	transferase activity
M	0016779	molecular_function	nucleotidyltransferase activity
M	0030643	biological_process	intracellular phosphate ion homeostasis
M	0034062	molecular_function	5'-3' RNA polymerase activity
M	0042789	biological_process	mRNA transcription by RNA polymerase II
M	0046872	molecular_function	metal ion binding
M	0140463	molecular_function	chromatin-protein adaptor activity
M	0180034	biological_process	co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway
N	0000428	cellular_component	DNA-directed RNA polymerase complex
N	0003676	molecular_function	nucleic acid binding
N	0003677	molecular_function	DNA binding
N	0003723	molecular_function	RNA binding
N	0003899	molecular_function	DNA-directed RNA polymerase activity
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005665	cellular_component	RNA polymerase II, core complex
N	0005721	cellular_component	pericentric heterochromatin
N	0005829	cellular_component	cytosol
N	0006351	biological_process	DNA-templated transcription
N	0006366	biological_process	transcription by RNA polymerase II
N	0006367	biological_process	transcription initiation at RNA polymerase II promoter
N	0008270	molecular_function	zinc ion binding
N	0016591	cellular_component	RNA polymerase II, holoenzyme
N	0016740	molecular_function	transferase activity
N	0016779	molecular_function	nucleotidyltransferase activity
N	0031047	biological_process	regulatory ncRNA-mediated gene silencing
N	0032549	molecular_function	ribonucleoside binding
N	0034062	molecular_function	5'-3' RNA polymerase activity
N	0046872	molecular_function	metal ion binding
N	0140727	biological_process	siRNA-mediated pericentric heterochromatin formation
O	0000428	cellular_component	DNA-directed RNA polymerase complex
O	0000785	cellular_component	chromatin
O	0003677	molecular_function	DNA binding
O	0003899	molecular_function	DNA-directed RNA polymerase activity
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005665	cellular_component	RNA polymerase II, core complex
O	0005829	cellular_component	cytosol
O	0006351	biological_process	DNA-templated transcription
O	0006366	biological_process	transcription by RNA polymerase II
O	0016591	cellular_component	RNA polymerase II, holoenzyme
O	0046983	molecular_function	protein dimerization activity
O	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
P	0000166	molecular_function	nucleotide binding
P	0000428	cellular_component	DNA-directed RNA polymerase complex
P	0003899	molecular_function	DNA-directed RNA polymerase activity
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005665	cellular_component	RNA polymerase II, core complex
P	0006352	biological_process	DNA-templated transcription initiation
P	0006366	biological_process	transcription by RNA polymerase II
P	0006367	biological_process	transcription initiation at RNA polymerase II promoter
P	0016591	cellular_component	RNA polymerase II, holoenzyme
P	0030880	cellular_component	RNA polymerase complex
P	0031369	molecular_function	translation initiation factor binding
Q	0000428	cellular_component	DNA-directed RNA polymerase complex
Q	0003677	molecular_function	DNA binding
Q	0003899	molecular_function	DNA-directed RNA polymerase activity
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005665	cellular_component	RNA polymerase II, core complex
Q	0005666	cellular_component	RNA polymerase III complex
Q	0005736	cellular_component	RNA polymerase I complex
Q	0005829	cellular_component	cytosol
Q	0006351	biological_process	DNA-templated transcription
Q	0006360	biological_process	transcription by RNA polymerase I
Q	0006362	biological_process	transcription elongation by RNA polymerase I
Q	0006366	biological_process	transcription by RNA polymerase II
Q	0006367	biological_process	transcription initiation at RNA polymerase II promoter
Q	0006383	biological_process	transcription by RNA polymerase III
Q	0016591	cellular_component	RNA polymerase II, holoenzyme
Q	0042797	biological_process	tRNA transcription by RNA polymerase III
R	0000428	cellular_component	DNA-directed RNA polymerase complex
R	0003677	molecular_function	DNA binding
R	0003899	molecular_function	DNA-directed RNA polymerase activity
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005665	cellular_component	RNA polymerase II, core complex
R	0005666	cellular_component	RNA polymerase III complex
R	0005736	cellular_component	RNA polymerase I complex
R	0005829	cellular_component	cytosol
R	0006351	biological_process	DNA-templated transcription
R	0006354	biological_process	DNA-templated transcription elongation
R	0006360	biological_process	transcription by RNA polymerase I
R	0006362	biological_process	transcription elongation by RNA polymerase I
R	0006366	biological_process	transcription by RNA polymerase II
R	0016591	cellular_component	RNA polymerase II, holoenzyme
R	0042797	biological_process	tRNA transcription by RNA polymerase III
S	0000428	cellular_component	DNA-directed RNA polymerase complex
S	0000932	cellular_component	P-body
S	0000956	biological_process	nuclear-transcribed mRNA catabolic process
S	0003676	molecular_function	nucleic acid binding
S	0003697	molecular_function	single-stranded DNA binding
S	0003727	molecular_function	single-stranded RNA binding
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005665	cellular_component	RNA polymerase II, core complex
S	0005829	cellular_component	cytosol
S	0006351	biological_process	DNA-templated transcription
S	0006352	biological_process	DNA-templated transcription initiation
S	0006367	biological_process	transcription initiation at RNA polymerase II promoter
S	0010590	biological_process	regulation of septum digestion after cytokinesis
S	0016591	cellular_component	RNA polymerase II, holoenzyme
S	0031369	molecular_function	translation initiation factor binding
S	0045948	biological_process	positive regulation of translational initiation
S	0060213	biological_process	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
T	0000428	cellular_component	DNA-directed RNA polymerase complex
T	0003677	molecular_function	DNA binding
T	0003899	molecular_function	DNA-directed RNA polymerase activity
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005665	cellular_component	RNA polymerase II, core complex
T	0005666	cellular_component	RNA polymerase III complex
T	0005736	cellular_component	RNA polymerase I complex
T	0005829	cellular_component	cytosol
T	0006351	biological_process	DNA-templated transcription
T	0006362	biological_process	transcription elongation by RNA polymerase I
T	0006366	biological_process	transcription by RNA polymerase II
T	0006383	biological_process	transcription by RNA polymerase III
T	0016591	cellular_component	RNA polymerase II, holoenzyme
U	0000428	cellular_component	DNA-directed RNA polymerase complex
U	0001193	biological_process	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
U	0003676	molecular_function	nucleic acid binding
U	0003899	molecular_function	DNA-directed RNA polymerase activity
U	0005634	cellular_component	nucleus
U	0005665	cellular_component	RNA polymerase II, core complex
U	0005730	cellular_component	nucleolus
U	0005829	cellular_component	cytosol
U	0006283	biological_process	transcription-coupled nucleotide-excision repair
U	0006351	biological_process	DNA-templated transcription
U	0006367	biological_process	transcription initiation at RNA polymerase II promoter
U	0008270	molecular_function	zinc ion binding
U	0016591	cellular_component	RNA polymerase II, holoenzyme
U	0046872	molecular_function	metal ion binding
V	0000428	cellular_component	DNA-directed RNA polymerase complex
V	0003677	molecular_function	DNA binding
V	0003899	molecular_function	DNA-directed RNA polymerase activity
V	0005634	cellular_component	nucleus
V	0005665	cellular_component	RNA polymerase II, core complex
V	0005666	cellular_component	RNA polymerase III complex
V	0005730	cellular_component	nucleolus
V	0005736	cellular_component	RNA polymerase I complex
V	0005829	cellular_component	cytosol
V	0006351	biological_process	DNA-templated transcription
V	0006360	biological_process	transcription by RNA polymerase I
V	0006362	biological_process	transcription elongation by RNA polymerase I
V	0006366	biological_process	transcription by RNA polymerase II
V	0006367	biological_process	transcription initiation at RNA polymerase II promoter
V	0006383	biological_process	transcription by RNA polymerase III
V	0008270	molecular_function	zinc ion binding
V	0016591	cellular_component	RNA polymerase II, holoenzyme
V	0042797	biological_process	tRNA transcription by RNA polymerase III
V	0046872	molecular_function	metal ion binding
W	0000428	cellular_component	DNA-directed RNA polymerase complex
W	0003677	molecular_function	DNA binding
W	0003899	molecular_function	DNA-directed RNA polymerase activity
W	0005634	cellular_component	nucleus
W	0005665	cellular_component	RNA polymerase II, core complex
W	0005829	cellular_component	cytosol
W	0006351	biological_process	DNA-templated transcription
W	0006366	biological_process	transcription by RNA polymerase II
W	0006367	biological_process	transcription initiation at RNA polymerase II promoter
W	0016591	cellular_component	RNA polymerase II, holoenzyme
W	0046983	molecular_function	protein dimerization activity
X	0000428	cellular_component	DNA-directed RNA polymerase complex
X	0003677	molecular_function	DNA binding
X	0003899	molecular_function	DNA-directed RNA polymerase activity
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005665	cellular_component	RNA polymerase II, core complex
X	0005666	cellular_component	RNA polymerase III complex
X	0005730	cellular_component	nucleolus
X	0005736	cellular_component	RNA polymerase I complex
X	0005829	cellular_component	cytosol
X	0006351	biological_process	DNA-templated transcription
X	0006360	biological_process	transcription by RNA polymerase I
X	0006362	biological_process	transcription elongation by RNA polymerase I
X	0006366	biological_process	transcription by RNA polymerase II
X	0006383	biological_process	transcription by RNA polymerase III
X	0008270	molecular_function	zinc ion binding
X	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 2456

Chain	Residue
A	CYS109
A	CYS112
A	CYS150
A	CYS175

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 2457

Chain	Residue
A	GLY61
A	CYS69
A	CYS79
A	HIS82

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 2225

Chain	Residue
B	CYS1155
B	SER1172
B	CYS1173
B	CYS1152

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 1269

Chain	Residue
C	CYS90
C	CYS92
C	CYS96
C	CYS99

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 1121

Chain	Residue
I	CYS7
I	CYS10
I	CYS29
I	CYS32

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN I 1122

Chain	Residue
I	CYS75
I	CYS78
I	HIS79
I	CYS103
I	CYS106

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN J 1066

Chain	Residue
J	CYS7
J	SER9
J	CYS10
J	CYS44
J	CYS45

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 1071

Chain	Residue
L	CYS24
L	CYS27
L	CYS41
L	CYS44

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN M 2456

Chain	Residue
M	CYS109
M	CYS150
M	CYS175
M	GLY176
M	ALA177

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN M 2457

Chain	Residue
M	GLY61
M	CYS69
M	CYS79
M	HIS82

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN N 2225

Chain	Residue
N	CYS1152
N	CYS1155
N	SER1172
N	CYS1173

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN O 1269

Chain	Residue
O	CYS90
O	CYS92
O	CYS96
O	CYS99

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN U 1121

Chain	Residue
U	CYS10
U	CYS29
U	ASN31
U	CYS32

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN U 1122

Chain	Residue
U	CYS75
U	CYS78
U	HIS79
U	CYS103
U	CYS106

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN V 1066

Chain	Residue
V	CYS7
V	SER9
V	CYS10
V	CYS44
V	CYS45

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN X 1071

Chain	Residue
X	CYS24
X	CYS27
X	CYS41
X	CYS44

---

Functional Information from PROSITE/UniProt

site_id	PS00115
Number of Residues	7
Details	RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPS

Chain	Residue	Details
A	TYR1578-SER1584
A	TYR1648-SER1654
A	TYR1655-SER1661
A	TYR1662-SER1668
A	TYR1669-SER1675
A	TYR1676-SER1682
A	TYR1683-SER1689
A	TYR1690-SER1696
A	TYR1697-SER1703
A	TYR1704-SER1710
A	TYR1711-SER1717
A	TYR1585-SER1591
A	TYR1718-SER1724
A	TYR1725-SER1731
A	TYR1732-SER1738
A	TYR1739-SER1745
A	TYR1746-SER1752
A	TYR1592-SER1598
A	TYR1599-SER1605
A	TYR1613-SER1619
A	TYR1620-SER1626
A	TYR1627-SER1633
A	TYR1634-SER1640
A	TYR1641-SER1647

---

site_id	PS00446
Number of Residues	41
Details	RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSLRRvvlaeiptvAidlVeinvNtSvmpDEfLAhRLGMIP

Chain	Residue	Details
C	ASN30-PRO70

---

site_id	PS00466
Number of Residues	36
Details	ZF_TFIIS_1 Zinc finger TFIIS-type signature. CprChqheavfyqTHSRRgDTMmtliyvCvh...CgfaF

Chain	Residue	Details
I	CYS75-PHE110

---

site_id	PS01030
Number of Residues	27
Details	RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. YCIECNNMLypredkvdrvlrlaCrnC

Chain	Residue	Details
I	TYR6-CYS32

---

site_id	PS01110
Number of Residues	14
Details	RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHilLspDE

Chain	Residue	Details
E	HIS142-GLU155

---

site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ

Chain	Residue	Details
F	THR76-GLN90

---

site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPIrCFSCG

Chain	Residue	Details
J	ILE2-GLY11

---

site_id	PS01154
Number of Residues	32
Details	RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. LekEdHTLaNmLanqLlsderVlfagYkvpHP

Chain	Residue	Details
K	LEU34-PRO65

---

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT

Chain	Residue	Details
B	GLY966-THR978

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	ZN_FING: C4-type => ECO:0000255

Chain	Residue	Details
L	CYS24-CYS44
A	ASP489
A	ASP491
M	CYS69
M	CYS72
M	CYS79
M	HIS82
M	CYS109
M	CYS112
M	CYS150
M	CYS175
X	CYS24-CYS44
M	ASP487
M	ASP489
M	ASP491
A	CYS79
A	HIS82
A	CYS109
A	CYS112
A	CYS150
A	CYS175
A	ASP487

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
L	CYS24
N	CYS1173
L	CYS27
L	CYS41
L	CYS44
X	CYS24
X	CYS27
X	CYS41
X	CYS44
N	CYS1170

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:18257517

Chain	Residue	Details
A	TYR1531
M	TYR1531
I	CYS29
I	CYS32
U	CYS7
U	CYS10
U	CYS29
U	CYS32

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P04050

Chain	Residue	Details
A	LYS1252
I	CYS78
M	LYS1252
I	CYS106
U	CYS75
U	CYS78
U	CYS103
U	CYS106

---