Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005833 | cellular_component | hemoglobin complex |
| A | 0015671 | biological_process | oxygen transport |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048821 | biological_process | erythrocyte development |
| B | 0005344 | molecular_function | oxygen carrier activity |
| B | 0005833 | cellular_component | hemoglobin complex |
| B | 0015671 | biological_process | oxygen transport |
| B | 0019825 | molecular_function | oxygen binding |
| B | 0020037 | molecular_function | heme binding |
| B | 0031721 | molecular_function | hemoglobin alpha binding |
| B | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048821 | biological_process | erythrocyte development |
| C | 0005344 | molecular_function | oxygen carrier activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0005833 | cellular_component | hemoglobin complex |
| C | 0015671 | biological_process | oxygen transport |
| C | 0019825 | molecular_function | oxygen binding |
| C | 0020037 | molecular_function | heme binding |
| C | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0048821 | biological_process | erythrocyte development |
| D | 0005344 | molecular_function | oxygen carrier activity |
| D | 0005833 | cellular_component | hemoglobin complex |
| D | 0015671 | biological_process | oxygen transport |
| D | 0019825 | molecular_function | oxygen binding |
| D | 0020037 | molecular_function | heme binding |
| D | 0031721 | molecular_function | hemoglobin alpha binding |
| D | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0048821 | biological_process | erythrocyte development |
| E | 0005344 | molecular_function | oxygen carrier activity |
| E | 0005506 | molecular_function | iron ion binding |
| E | 0005833 | cellular_component | hemoglobin complex |
| E | 0015671 | biological_process | oxygen transport |
| E | 0019825 | molecular_function | oxygen binding |
| E | 0020037 | molecular_function | heme binding |
| E | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0048821 | biological_process | erythrocyte development |
| F | 0005344 | molecular_function | oxygen carrier activity |
| F | 0005833 | cellular_component | hemoglobin complex |
| F | 0015671 | biological_process | oxygen transport |
| F | 0019825 | molecular_function | oxygen binding |
| F | 0020037 | molecular_function | heme binding |
| F | 0031721 | molecular_function | hemoglobin alpha binding |
| F | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0048821 | biological_process | erythrocyte development |
| G | 0005344 | molecular_function | oxygen carrier activity |
| G | 0005506 | molecular_function | iron ion binding |
| G | 0005833 | cellular_component | hemoglobin complex |
| G | 0015671 | biological_process | oxygen transport |
| G | 0019825 | molecular_function | oxygen binding |
| G | 0020037 | molecular_function | heme binding |
| G | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0048821 | biological_process | erythrocyte development |
| H | 0005344 | molecular_function | oxygen carrier activity |
| H | 0005833 | cellular_component | hemoglobin complex |
| H | 0015671 | biological_process | oxygen transport |
| H | 0019825 | molecular_function | oxygen binding |
| H | 0020037 | molecular_function | heme binding |
| H | 0031721 | molecular_function | hemoglobin alpha binding |
| H | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0048821 | biological_process | erythrocyte development |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM A 143 |
| Chain | Residue |
| A | TYR42 |
| A | ASN97 |
| A | PHE98 |
| A | LEU101 |
| A | LEU136 |
| A | HOH142 |
| A | PHE43 |
| A | HIS45 |
| A | HIS58 |
| A | LYS61 |
| A | LEU86 |
| A | HIS87 |
| A | LEU91 |
| A | VAL93 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE HEM B 148 |
| Chain | Residue |
| B | PHE41 |
| B | PHE42 |
| B | HIS63 |
| B | HIS92 |
| B | LEU96 |
| B | ASN102 |
| B | PHE103 |
| B | LEU106 |
| B | LEU141 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM C 143 |
| Chain | Residue |
| C | TYR42 |
| C | PHE43 |
| C | HIS45 |
| C | PHE46 |
| C | HIS58 |
| C | LYS61 |
| C | ALA65 |
| C | LEU86 |
| C | HIS87 |
| C | LEU91 |
| C | VAL93 |
| C | PHE98 |
| C | LEU101 |
| C | HOH142 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM D 148 |
| Chain | Residue |
| D | PHE41 |
| D | PHE42 |
| D | HIS63 |
| D | LYS66 |
| D | VAL67 |
| D | SER70 |
| D | LEU88 |
| D | HIS92 |
| D | LEU96 |
| D | ASN102 |
| D | LEU106 |
| D | LEU141 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM E 143 |
| Chain | Residue |
| E | TYR42 |
| E | PHE43 |
| E | HIS45 |
| E | PHE46 |
| E | HIS58 |
| E | LYS61 |
| E | ALA65 |
| E | LEU83 |
| E | HIS87 |
| E | VAL93 |
| E | ASN97 |
| E | PHE98 |
| E | LEU101 |
| E | HOH142 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM F 148 |
| Chain | Residue |
| F | THR38 |
| F | PHE41 |
| F | PHE42 |
| F | HIS63 |
| F | LYS66 |
| F | HIS92 |
| F | LEU96 |
| F | VAL98 |
| F | ASN102 |
| F | LEU106 |
| F | LEU141 |
| F | HOH147 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM G 143 |
| Chain | Residue |
| G | TYR42 |
| G | PHE43 |
| G | HIS45 |
| G | PHE46 |
| G | LYS61 |
| G | VAL62 |
| G | LEU83 |
| G | HIS87 |
| G | LEU91 |
| G | VAL93 |
| G | ASN97 |
| G | PHE98 |
| G | LEU101 |
| G | LEU136 |
| G | HOH144 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM H 148 |
| Chain | Residue |
| H | ASN102 |
| H | PHE103 |
| H | LEU106 |
| H | LEU141 |
| H | THR38 |
| H | PHE41 |
| H | PHE42 |
| H | HIS63 |
| H | SER70 |
| H | LEU88 |
| H | LEU91 |
| H | HIS92 |
| H | LEU96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Peptide: {"description":"Hemopressin","featureId":"PRO_0000455877","evidences":[{"source":"UniProtKB","id":"P01946","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"proximal binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P69905","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P01942","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P01942","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P69905","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 12 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P01942","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 12 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P01942","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 576 |
| Details | Domain: {"description":"Globin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"distal binding residue"} |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Binding site: {"description":"proximal binding residue"} |
| site_id | SWS_FT_FI13 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P68871","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI14 |
| Number of Residues | 12 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P68871","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI15 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"UniProtKB","id":"P68871","evidenceCode":"ECO:0000250"}]} |
