3GYQ
Structure of the Thiostrepton-Resistance Methyltransferase S-adenosyl-L-methionine Complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0006396 | biological_process | RNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008173 | molecular_function | RNA methyltransferase activity |
| A | 0008649 | molecular_function | rRNA methyltransferase activity |
| A | 0030743 | molecular_function | 23S rRNA (adenosine(1067)-2'-O)-methyltransferase activity |
| A | 0031167 | biological_process | rRNA methylation |
| A | 0032259 | biological_process | methylation |
| A | 0046677 | biological_process | response to antibiotic |
| B | 0003723 | molecular_function | RNA binding |
| B | 0006396 | biological_process | RNA processing |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008173 | molecular_function | RNA methyltransferase activity |
| B | 0008649 | molecular_function | rRNA methyltransferase activity |
| B | 0030743 | molecular_function | 23S rRNA (adenosine(1067)-2'-O)-methyltransferase activity |
| B | 0031167 | biological_process | rRNA methylation |
| B | 0032259 | biological_process | methylation |
| B | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE SAM A 270 |
| Chain | Residue |
| A | LEU195 |
| A | SER237 |
| A | ILE238 |
| A | MET240 |
| A | SER246 |
| A | LEU247 |
| A | SER252 |
| B | ARG135 |
| B | ARG165 |
| A | LYS196 |
| A | ALA197 |
| A | PHE217 |
| A | GLY218 |
| A | SER219 |
| A | GLU220 |
| A | LYS221 |
| A | VAL236 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE SAM B 270 |
| Chain | Residue |
| A | ARG135 |
| B | LEU195 |
| B | LYS196 |
| B | ALA197 |
| B | GLY218 |
| B | SER219 |
| B | GLU220 |
| B | LYS221 |
| B | GLY223 |
| B | VAL236 |
| B | SER237 |
| B | ILE238 |
| B | MET240 |
| B | SER246 |
| B | LEU247 |
| B | VAL249 |
| B | SER252 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19369248, ECO:0007744|PDB:3GYQ |
| Chain | Residue | Details |
| B | ARG135 | |
| B | ARG165 | |
| B | LEU195 | |
| B | GLY218 | |
| B | ILE238 | |
| B | LEU247 | |
| A | LEU247 | |
| A | ARG135 | |
| A | ARG165 | |
| A | LEU195 | |
| A | GLY218 | |
| A | ILE238 |
