3GYH
Crystal Structure Analysis of S. Pombe ATL in complex with damaged DNA containing POB
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| X | 0003677 | molecular_function | DNA binding |
| X | 0003684 | molecular_function | damaged DNA binding |
| X | 0003824 | molecular_function | catalytic activity |
| X | 0003908 | molecular_function | methylated-DNA-[protein]-cysteine S-methyltransferase activity |
| X | 0005634 | cellular_component | nucleus |
| X | 0005829 | cellular_component | cytosol |
| X | 0006281 | biological_process | DNA repair |
| X | 0006283 | biological_process | transcription-coupled nucleotide-excision repair |
| X | 0006974 | biological_process | DNA damage response |
| X | 0032132 | molecular_function | O6-alkylguanine-DNA binding |
| X | 0070911 | biological_process | global genome nucleotide-excision repair |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PBO Y 200 |
| Chain | Residue |
| X | MET45 |
| X | LEU48 |
| X | PRO50 |
| X | TRP56 |
| X | ARG77 |
| X | ARG81 |
| Y | DG207 |
| Y | DG211 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Site: {"description":"Required for phosphate rotation/nucleotide flipping","evidences":[{"source":"PubMed","id":"19516334","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Arg finger, required for nucleotide flipping","evidences":[{"source":"PubMed","id":"19516334","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Critical for recognition of O(6)-alkylguanines, probes the electrostatic potential of the flipped base to distinguish between O(6)-alkylguanine and guanine","evidences":[{"source":"PubMed","id":"23112169","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
