Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 247 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH275 |
| A | HOH279 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE BEN A 1 |
| Chain | Residue |
| A | SER195 |
| A | VAL213 |
| A | GLY219 |
| A | GLY226 |
| A | SO4249 |
| A | HOH280 |
| A | HOH455 |
| A | ASP189 |
| A | SER190 |
| A | GLN192 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 246 |
| Chain | Residue |
| A | ASN95 |
| A | THR98 |
| A | ASN100 |
| A | HOH374 |
| A | HOH436 |
| A | HOH473 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 2 |
| Chain | Residue |
| A | EDO3 |
| A | ASN97 |
| A | LEU99 |
| A | LYS159 |
| A | TRP215 |
| A | HOH381 |
| A | HOH468 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 3 |
| Chain | Residue |
| A | EDO2 |
| A | GLN135 |
| A | LEU137 |
| A | LYS159 |
| A | HOH259 |
| A | HOH344 |
| A | HOH453 |
| A | HOH475 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 4 |
| Chain | Residue |
| A | ALA129 |
| A | ASP165 |
| A | PHE181 |
| A | LYS230 |
| A | HOH327 |
| A | HOH425 |
| A | HOH441 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 248 |
| Chain | Residue |
| A | LYS87 |
| A | LYS107 |
| A | THR149 |
| A | TYR151 |
| A | HOH297 |
| A | HOH319 |
| A | HOH411 |
| A | HOH445 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 249 |
| Chain | Residue |
| A | BEN1 |
| A | HIS57 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | HOH328 |
| A | HOH447 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 250 |
| Chain | Residue |
| A | PRO124 |
| A | THR125 |
| A | SER127 |
| A | SER147 |
| A | GLY148 |
| A | LYS204 |
| A | HOH205 |
| A | HOH336 |
| A | HOH429 |
| A | HOH434 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 251 |
| Chain | Residue |
| A | LYS145 |
| A | SER146 |
| A | SER147 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 5 |
| Chain | Residue |
| A | SO46 |
| A | THR177 |
| A | SER178 |
| A | HOH405 |
| A | HOH435 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 6 |
| Chain | Residue |
| A | SO45 |
| A | SER178 |
| A | ASN179 |
| A | HOH390 |
| A | HOH405 |
| A | HOH451 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 7 |
| Chain | Residue |
| A | PRO173 |
| A | GLY174 |
| A | HOH302 |
| A | HOH361 |
| A | HOH403 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | VAL75 | |
| A | GLU80 | |
| A | ASP189 | |
| A | GLN192 | |
| A | SER195 | |
| A | ASN72 | |
