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3GWU

Leucine transporter LeuT in complex with sertraline

Functional Information from GO Data
ChainGOidnamespacecontents
A0005886cellular_componentplasma membrane
A0016020cellular_componentmembrane
A0035725biological_processsodium ion transmembrane transport
Functional Information from PDB Data
site_idAC1
Number of Residues12
DetailsBINDING SITE FOR RESIDUE LEU A 601
ChainResidue
AASN21
ASER256
APHE259
ANA752
AALA22
AGLY24
ALEU25
AGLY26
AASN27
ATYR108
APHE253
ATHR254

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 751
ChainResidue
AGLY20
AVAL23
AGLY24
AALA351
ATHR354
ASER355

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE NA A 752
ChainResidue
AALA22
AASN27
ATHR254
AASN286
ALEU601

site_idAC4
Number of Residues10
DetailsBINDING SITE FOR RESIDUE SRE A 801
ChainResidue
ALEU29
AARG30
ATYR108
APHE253
AALA319
ALEU400
AASP401
AASP404
ATHR409
AHOH933

229380

PDB entries from 2024-12-25

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