3GQT
Crystal structure of glutaryl-CoA dehydrogenase from Burkholderia pseudomallei with fragment (1,4-dimethyl-1,2,3,4-tetrahydroquinoxalin-6-yl)methylamine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000062 | molecular_function | fatty-acyl-CoA binding |
| A | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| A | 0004361 | molecular_function | glutaryl-CoA dehydrogenase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0033539 | biological_process | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
| A | 0046949 | biological_process | fatty-acyl-CoA biosynthetic process |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000062 | molecular_function | fatty-acyl-CoA binding |
| B | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| B | 0004361 | molecular_function | glutaryl-CoA dehydrogenase activity |
| B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| B | 0033539 | biological_process | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
| B | 0046949 | biological_process | fatty-acyl-CoA biosynthetic process |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0000062 | molecular_function | fatty-acyl-CoA binding |
| C | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| C | 0004361 | molecular_function | glutaryl-CoA dehydrogenase activity |
| C | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| C | 0033539 | biological_process | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
| C | 0046949 | biological_process | fatty-acyl-CoA biosynthetic process |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0000062 | molecular_function | fatty-acyl-CoA binding |
| D | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| D | 0004361 | molecular_function | glutaryl-CoA dehydrogenase activity |
| D | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| D | 0033539 | biological_process | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
| D | 0046949 | biological_process | fatty-acyl-CoA biosynthetic process |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE UFO A 1000 |
| Chain | Residue |
| A | GLY350 |
| A | GLY351 |
| A | ASN352 |
| C | TRP169 |
| C | THR171 |
| C | LYS213 |
| C | LEU216 |
| C | THR221 |
| C | TYR373 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE UFO B 1001 |
| Chain | Residue |
| B | THR139 |
| B | TYR373 |
| B | GLU374 |
| D | UFO1000 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE UFO D 1000 |
| Chain | Residue |
| B | LYS213 |
| B | THR221 |
| B | TYR373 |
| B | UFO1001 |
| D | GLY350 |
| D | GLY351 |
| D | ASN352 |
Functional Information from PROSITE/UniProt
| site_id | PS00073 |
| Number of Residues | 20 |
| Details | ACYL_COA_DH_2 Acyl-CoA dehydrogenases signature 2. DmLGGnGIsdEfgvaRhlvN |
| Chain | Residue | Details |
| A | ASP347-ASN366 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| A | ALA253 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| B | ALA253 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| C | ALA253 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| D | ALA253 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| B | GLU374 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| C | GLU374 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ivh |
| Chain | Residue | Details |
| D | GLU374 |
