3GON

Streptococcus pneumoniae Phosphomevalonate Kinase in Complex with Phosphomevalonate and AMPPNP

Replaces:  2PG9

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004631	molecular_function	phosphomevalonate kinase activity
A	0005524	molecular_function	ATP binding
A	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE PMV A 400

Chain	Residue
A	LYS9
A	ALA293
A	HOH336
A	HOH337
A	HOH338
A	HOH344
A	HOH346
A	ANP500
A	HOH517
A	MG600
A	TYR11
A	GLU15
A	TYR16
A	ILE18
A	GLY146
A	SER147
A	SER213
A	GLY292

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ANP A 500

Chain	Residue
A	LYS9
A	MET34
A	SER48
A	MET50
A	PHE51
A	LYS101
A	GLY103
A	GLY105
A	SER106
A	SER107
A	SER213
A	ASP297
A	HOH336
A	HOH337
A	HOH341
A	PMV400
A	HOH414
A	MG600

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 600

Chain	Residue
A	ASP297
A	HOH336
A	HOH337
A	HOH338
A	PMV400
A	ANP500

---