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3GON

Streptococcus pneumoniae Phosphomevalonate Kinase in Complex with Phosphomevalonate and AMPPNP

Replaces:  2PG9
Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0005524molecular_functionATP binding
A0016020cellular_componentmembrane
A0016301molecular_functionkinase activity
A0016740molecular_functiontransferase activity
A0019287biological_processisopentenyl diphosphate biosynthetic process, mevalonate pathway
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE PMV A 400
ChainResidue
ALYS9
AALA293
AHOH336
AHOH337
AHOH338
AHOH344
AHOH346
AANP500
AHOH517
AMG600
ATYR11
AGLU15
ATYR16
AILE18
AGLY146
ASER147
ASER213
AGLY292

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE ANP A 500
ChainResidue
ALYS9
AMET34
ASER48
AMET50
APHE51
ALYS101
AGLY103
AGLY105
ASER106
ASER107
ASER213
AASP297
AHOH336
AHOH337
AHOH341
APMV400
AHOH414
AMG600

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 600
ChainResidue
AASP297
AHOH336
AHOH337
AHOH338
APMV400
AANP500

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PDB entries from 2025-06-18

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