Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3GNQ

Crystal structure of glyceraldehyde-3-phosphate dehydrogenase, type I from Burkholderia pseudomallei

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A	0005829	cellular_component	cytosol
A	0006006	biological_process	glucose metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0048046	cellular_component	apoplast
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding
B	0000166	molecular_function	nucleotide binding
B	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B	0005829	cellular_component	cytosol
B	0006006	biological_process	glucose metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0048046	cellular_component	apoplast
B	0050661	molecular_function	NADP binding
B	0051287	molecular_function	NAD binding
C	0000166	molecular_function	nucleotide binding
C	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C	0005829	cellular_component	cytosol
C	0006006	biological_process	glucose metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0048046	cellular_component	apoplast
C	0050661	molecular_function	NADP binding
C	0051287	molecular_function	NAD binding
D	0000166	molecular_function	nucleotide binding
D	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D	0005829	cellular_component	cytosol
D	0006006	biological_process	glucose metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0048046	cellular_component	apoplast
D	0050661	molecular_function	NADP binding
D	0051287	molecular_function	NAD binding
E	0000166	molecular_function	nucleotide binding
E	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E	0005829	cellular_component	cytosol
E	0006006	biological_process	glucose metabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
E	0048046	cellular_component	apoplast
E	0050661	molecular_function	NADP binding
E	0051287	molecular_function	NAD binding
F	0000166	molecular_function	nucleotide binding
F	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F	0005829	cellular_component	cytosol
F	0006006	biological_process	glucose metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
F	0048046	cellular_component	apoplast
F	0050661	molecular_function	NADP binding
F	0051287	molecular_function	NAD binding
G	0000166	molecular_function	nucleotide binding
G	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G	0005829	cellular_component	cytosol
G	0006006	biological_process	glucose metabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
G	0048046	cellular_component	apoplast
G	0050661	molecular_function	NADP binding
G	0051287	molecular_function	NAD binding
H	0000166	molecular_function	nucleotide binding
H	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H	0005829	cellular_component	cytosol
H	0006006	biological_process	glucose metabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
H	0048046	cellular_component	apoplast
H	0050661	molecular_function	NADP binding
H	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	BINDING SITE FOR RESIDUE NAD B 901

Chain	Residue
B	GLY8
B	THR99
B	GLY100
B	PHE101
B	SER122
B	ALA123
B	CYS154
B	ASN185
B	ASN316
B	PHE320
B	HOH348
B	GLY10
B	HOH350
B	HOH360
B	HOH381
B	HOH517
B	HOH530
B	ARG11
B	ILE12
B	ASN35
B	ASP36
B	LEU37
B	ARG80
B	CYS98

site_id	AC2
Number of Residues	29
Details	BINDING SITE FOR RESIDUE NAD C 901

Chain	Residue
C	GLY8
C	TYR9
C	GLY10
C	ARG11
C	ILE12
C	ASN35
C	ASP36
C	ARG80
C	CYS98
C	THR99
C	GLY100
C	SER122
C	ALA123
C	CYS154
C	ASN185
C	ASN316
C	PHE320
C	HOH337
C	HOH341
C	HOH343
C	HOH364
C	HOH365
C	HOH369
C	HOH372
C	HOH383
C	HOH384
C	HOH395
D	VAL192
D	TYR193

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE NAD D 901

Chain	Residue
C	VAL192
D	GLY10
D	ARG11
D	ILE12
D	ASP36
D	CYS98
D	THR99
D	SER122
D	CYS154
D	ASN185
D	ASN316
D	HOH344

site_id	AC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE NAD E 901

Chain	Residue
E	GLY8
E	GLY10
E	ARG11
E	ILE12
E	ASP36
E	CYS98
E	PHE101
E	SER122
E	CYS154
E	ASN185
E	ASN316
E	PHE320
E	HOH352
F	VAL192

site_id	AC5
Number of Residues	24
Details	BINDING SITE FOR RESIDUE NAD F 901

Chain	Residue
F	HOH344
F	HOH349
F	HOH350
F	HOH473
F	GLY8
F	GLY10
F	ARG11
F	ILE12
F	ASN35
F	ASP36
F	LEU37
F	ARG80
F	CYS98
F	THR99
F	GLY100
F	SER122
F	ALA123
F	CYS154
F	ASN185
F	ASN316
F	PHE320
F	HOH338
F	HOH339
F	HOH341

site_id	AC6
Number of Residues	19
Details	BINDING SITE FOR RESIDUE NAD G 901

Chain	Residue
G	ASN7
G	GLY8
G	GLY10
G	ARG11
G	ILE12
G	ASP36
G	ARG80
G	CYS98
G	THR99
G	GLY100
G	SER122
G	ALA123
G	THR184
G	ASN185
G	ASN316
G	HOH343
G	HOH344
G	HOH355
G	HOH487

site_id	AC7
Number of Residues	28
Details	BINDING SITE FOR RESIDUE NAD H 901

Chain	Residue
G	VAL192
H	GLY8
H	TYR9
H	GLY10
H	ARG11
H	ILE12
H	ASN35
H	ASP36
H	LEU37
H	ARG80
H	CYS98
H	THR99
H	GLY100
H	SER122
H	ALA123
H	CYS154
H	THR184
H	ASN185
H	ASN316
H	PHE320
H	HOH341
H	HOH353
H	HOH355
H	HOH356
H	HOH360
H	HOH380
H	HOH499
H	HOH527

Functional Information from PROSITE/UniProt

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL

Chain	Residue	Details
A	ALA152-LEU159

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)