3GMC
Crystal Structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid Oxygenase with substrate bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0047081 | molecular_function | 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity |
| A | 0071949 | molecular_function | FAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0047081 | molecular_function | 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity |
| B | 0071949 | molecular_function | FAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE FAD A 380 |
| Chain | Residue |
| A | GLY18 |
| A | TYR54 |
| A | ARG106 |
| A | SER128 |
| A | GLU129 |
| A | ALA130 |
| A | ALA155 |
| A | ASP156 |
| A | GLY157 |
| A | LEU179 |
| A | ARG181 |
| A | GLY19 |
| A | TYR270 |
| A | GLY287 |
| A | ASP288 |
| A | GLY300 |
| A | ALA301 |
| A | GLY302 |
| A | 3HM381 |
| A | HOH384 |
| A | HOH423 |
| A | HOH426 |
| A | GLY20 |
| A | HOH482 |
| A | HOH484 |
| A | HOH512 |
| A | HOH601 |
| A | HOH620 |
| A | HOH654 |
| A | PHE21 |
| A | ALA22 |
| A | HIS40 |
| A | GLU41 |
| A | LYS42 |
| A | ILE53 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 3HM A 381 |
| Chain | Residue |
| A | TYR54 |
| A | ARG211 |
| A | LEU213 |
| A | PRO295 |
| A | ALA296 |
| A | ALA298 |
| A | FAD380 |
| A | HOH435 |
| A | HOH484 |
| A | HOH493 |
| A | HOH546 |
| A | HOH654 |
| site_id | AC3 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE FAD B 380 |
| Chain | Residue |
| B | GLY18 |
| B | GLY19 |
| B | GLY20 |
| B | PHE21 |
| B | ALA22 |
| B | HIS40 |
| B | GLU41 |
| B | LYS42 |
| B | ILE53 |
| B | TYR54 |
| B | ARG106 |
| B | SER128 |
| B | GLU129 |
| B | ALA130 |
| B | ALA155 |
| B | ASP156 |
| B | GLY157 |
| B | LEU179 |
| B | ARG181 |
| B | TYR270 |
| B | GLY287 |
| B | ASP288 |
| B | GLY300 |
| B | ALA301 |
| B | GLY302 |
| B | 3HM381 |
| B | HOH383 |
| B | HOH402 |
| B | HOH462 |
| B | HOH463 |
| B | HOH479 |
| B | HOH502 |
| B | HOH517 |
| B | HOH527 |
| B | HOH657 |
| B | HOH705 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 3HM B 381 |
| Chain | Residue |
| B | TYR54 |
| B | ARG211 |
| B | LEU213 |
| B | MET227 |
| B | PRO295 |
| B | ALA296 |
| B | ALA298 |
| B | LEU352 |
| B | FAD380 |
| B | HOH463 |
| B | HOH480 |
| B | HOH481 |
| B | HOH517 |
| B | HOH726 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19317437","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27568368","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ALJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ALL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ALM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GMC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GF7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HXI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27568368","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4JY3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19317437","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GMC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4H2Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19317437","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GMC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
