Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3GLH

Crystal Structure of the E. coli clamp loader bound to Psi Peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003689	molecular_function	DNA clamp loader activity
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005515	molecular_function	protein binding
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0009360	cellular_component	DNA polymerase III complex
A	0030894	cellular_component	replisome
A	0043846	cellular_component	DNA polymerase III, clamp loader complex
A	0071897	biological_process	DNA biosynthetic process
B	0003677	molecular_function	DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005524	molecular_function	ATP binding
B	0006260	biological_process	DNA replication
B	0009360	cellular_component	DNA polymerase III complex
B	0016887	molecular_function	ATP hydrolysis activity
C	0003677	molecular_function	DNA binding
C	0003887	molecular_function	DNA-directed DNA polymerase activity
C	0005524	molecular_function	ATP binding
C	0006260	biological_process	DNA replication
C	0009360	cellular_component	DNA polymerase III complex
C	0016887	molecular_function	ATP hydrolysis activity
D	0003677	molecular_function	DNA binding
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0005524	molecular_function	ATP binding
D	0006260	biological_process	DNA replication
D	0009360	cellular_component	DNA polymerase III complex
D	0016887	molecular_function	ATP hydrolysis activity
E	0003677	molecular_function	DNA binding
E	0003689	molecular_function	DNA clamp loader activity
E	0003887	molecular_function	DNA-directed DNA polymerase activity
E	0005515	molecular_function	protein binding
E	0006260	biological_process	DNA replication
E	0006261	biological_process	DNA-templated DNA replication
E	0008408	molecular_function	3'-5' exonuclease activity
E	0009360	cellular_component	DNA polymerase III complex
E	0030894	cellular_component	replisome
E	0043846	cellular_component	DNA polymerase III, clamp loader complex
E	0071897	biological_process	DNA biosynthetic process
F	0003677	molecular_function	DNA binding
F	0003689	molecular_function	DNA clamp loader activity
F	0003887	molecular_function	DNA-directed DNA polymerase activity
F	0005515	molecular_function	protein binding
F	0006260	biological_process	DNA replication
F	0006261	biological_process	DNA-templated DNA replication
F	0009360	cellular_component	DNA polymerase III complex
F	0030894	cellular_component	replisome
F	0043846	cellular_component	DNA polymerase III, clamp loader complex
F	0071897	biological_process	DNA biosynthetic process
G	0003677	molecular_function	DNA binding
G	0003887	molecular_function	DNA-directed DNA polymerase activity
G	0005524	molecular_function	ATP binding
G	0006260	biological_process	DNA replication
G	0009360	cellular_component	DNA polymerase III complex
G	0016887	molecular_function	ATP hydrolysis activity
H	0003677	molecular_function	DNA binding
H	0003887	molecular_function	DNA-directed DNA polymerase activity
H	0005524	molecular_function	ATP binding
H	0006260	biological_process	DNA replication
H	0009360	cellular_component	DNA polymerase III complex
H	0016887	molecular_function	ATP hydrolysis activity
I	0003677	molecular_function	DNA binding
I	0003887	molecular_function	DNA-directed DNA polymerase activity
I	0005524	molecular_function	ATP binding
I	0006260	biological_process	DNA replication
I	0009360	cellular_component	DNA polymerase III complex
I	0016887	molecular_function	ATP hydrolysis activity
J	0003677	molecular_function	DNA binding
J	0003689	molecular_function	DNA clamp loader activity
J	0003887	molecular_function	DNA-directed DNA polymerase activity
J	0005515	molecular_function	protein binding
J	0006260	biological_process	DNA replication
J	0006261	biological_process	DNA-templated DNA replication
J	0008408	molecular_function	3'-5' exonuclease activity
J	0009360	cellular_component	DNA polymerase III complex
J	0030894	cellular_component	replisome
J	0043846	cellular_component	DNA polymerase III, clamp loader complex
J	0071897	biological_process	DNA biosynthetic process
K	0003677	molecular_function	DNA binding
K	0003689	molecular_function	DNA clamp loader activity
K	0003887	molecular_function	DNA-directed DNA polymerase activity
K	0005515	molecular_function	protein binding
K	0006260	biological_process	DNA replication
K	0006261	biological_process	DNA-templated DNA replication
K	0009360	cellular_component	DNA polymerase III complex
K	0030894	cellular_component	replisome
K	0043846	cellular_component	DNA polymerase III, clamp loader complex
K	0071897	biological_process	DNA biosynthetic process
L	0003677	molecular_function	DNA binding
L	0003887	molecular_function	DNA-directed DNA polymerase activity
L	0005524	molecular_function	ATP binding
L	0006260	biological_process	DNA replication
L	0009360	cellular_component	DNA polymerase III complex
L	0016887	molecular_function	ATP hydrolysis activity
M	0003677	molecular_function	DNA binding
M	0003887	molecular_function	DNA-directed DNA polymerase activity
M	0005524	molecular_function	ATP binding
M	0006260	biological_process	DNA replication
M	0009360	cellular_component	DNA polymerase III complex
M	0016887	molecular_function	ATP hydrolysis activity
N	0003677	molecular_function	DNA binding
N	0003887	molecular_function	DNA-directed DNA polymerase activity
N	0005524	molecular_function	ATP binding
N	0006260	biological_process	DNA replication
N	0009360	cellular_component	DNA polymerase III complex
N	0016887	molecular_function	ATP hydrolysis activity
O	0003677	molecular_function	DNA binding
O	0003689	molecular_function	DNA clamp loader activity
O	0003887	molecular_function	DNA-directed DNA polymerase activity
O	0005515	molecular_function	protein binding
O	0006260	biological_process	DNA replication
O	0006261	biological_process	DNA-templated DNA replication
O	0008408	molecular_function	3'-5' exonuclease activity
O	0009360	cellular_component	DNA polymerase III complex
O	0030894	cellular_component	replisome
O	0043846	cellular_component	DNA polymerase III, clamp loader complex
O	0071897	biological_process	DNA biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
B	GLY45
C	GLY45
D	GLY45
G	GLY45
H	GLY45
I	GLY45
L	GLY45
M	GLY45
N	GLY45

site_id	SWS_FT_FI2
Number of Residues	36
Details	BINDING: BINDING => ECO:0000269\|PubMed:11525729, ECO:0007744\|PDB:1JR3

Chain	Residue	Details
B	CYS64
D	CYS73
D	CYS76
D	CYS79
G	CYS64
G	CYS73
G	CYS76
G	CYS79
H	CYS64
H	CYS73
H	CYS76
B	CYS73
H	CYS79
I	CYS64
I	CYS73
I	CYS76
I	CYS79
L	CYS64
L	CYS73
L	CYS76
L	CYS79
M	CYS64
B	CYS76
M	CYS73
M	CYS76
M	CYS79
N	CYS64
N	CYS73
N	CYS76
N	CYS79
B	CYS79
C	CYS64
C	CYS73
C	CYS76
C	CYS79
D	CYS64

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
B	VAL253

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
B	ARG215
B	LYS51
B	LYS141

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
C	ARG215
C	LYS51
C	LYS141

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
D	ARG215
D	LYS51
D	LYS141

site_id	CSA13
Number of Residues	3
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
G	ARG215
G	LYS51
G	LYS141

site_id	CSA14
Number of Residues	3
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
H	ARG215
H	LYS51
H	LYS141

site_id	CSA15
Number of Residues	3
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
I	ARG215
I	LYS51
I	LYS141

site_id	CSA16
Number of Residues	3
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
L	ARG215
L	LYS51
L	LYS141

site_id	CSA17
Number of Residues	3
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
M	ARG215
M	LYS51
M	LYS141

site_id	CSA18
Number of Residues	3
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
N	ARG215
N	LYS51
N	LYS141

site_id	CSA19
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
B	ARG215
B	THR157

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
C	VAL253

site_id	CSA20
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
C	ARG215
C	THR157

site_id	CSA21
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
D	ARG215
D	THR157

site_id	CSA22
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
G	ARG215
G	THR157

site_id	CSA23
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
H	ARG215
H	THR157

site_id	CSA24
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
I	ARG215
I	THR157

site_id	CSA25
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
L	ARG215
L	THR157

site_id	CSA26
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
M	ARG215
M	THR157

site_id	CSA27
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
N	ARG215
N	THR157

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
D	VAL253

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
G	VAL253

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
H	VAL253

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
I	VAL253

site_id	CSA7
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
L	VAL253

site_id	CSA8
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
M	VAL253

site_id	CSA9
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8p

Chain	Residue	Details
N	VAL253

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)