3GL9
The structure of a histidine kinase-response regulator complex sheds light into two-component signaling and reveals a novel cis autophosphorylation mechanism
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000156 | molecular_function | phosphorelay response regulator activity |
| A | 0000160 | biological_process | phosphorelay signal transduction system |
| A | 0003677 | molecular_function | DNA binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000156 | molecular_function | phosphorelay response regulator activity |
| B | 0000160 | biological_process | phosphorelay signal transduction system |
| B | 0003677 | molecular_function | DNA binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000156 | molecular_function | phosphorelay response regulator activity |
| C | 0000160 | biological_process | phosphorelay signal transduction system |
| C | 0003677 | molecular_function | DNA binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000156 | molecular_function | phosphorelay response regulator activity |
| D | 0000160 | biological_process | phosphorelay signal transduction system |
| D | 0003677 | molecular_function | DNA binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 123 |
| Chain | Residue |
| A | ASP10 |
| A | BFD53 |
| A | MET55 |
| A | HOH148 |
| A | HOH368 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 124 |
| Chain | Residue |
| A | HOH367 |
| A | HOH436 |
| A | HOH490 |
| A | HOH651 |
| D | GLY87 |
| D | GLU88 |
| D | HOH137 |
| A | ARG100 |
| A | GLU115 |
| A | HIS118 |
| A | LEU119 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 123 |
| Chain | Residue |
| B | ASP10 |
| B | BFD53 |
| B | MET55 |
| B | HOH149 |
| B | HOH369 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 124 |
| Chain | Residue |
| B | GLY86 |
| B | GLY87 |
| B | ARG100 |
| B | HIS118 |
| B | LEU119 |
| B | GLU122 |
| B | HOH159 |
| B | HOH171 |
| B | HOH563 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 123 |
| Chain | Residue |
| C | ASP10 |
| C | BFD53 |
| C | MET55 |
| C | HOH166 |
| C | HOH194 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 124 |
| Chain | Residue |
| A | GLY87 |
| A | GLU88 |
| A | HOH276 |
| C | ARG100 |
| C | GLU115 |
| C | HIS118 |
| C | HOH141 |
| C | HOH154 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 123 |
| Chain | Residue |
| D | ASP10 |
| D | BFD53 |
| D | MET55 |
| D | HOH157 |
| D | HOH174 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 124 |
| Chain | Residue |
| C | GLY87 |
| C | GLU88 |
| C | HOH241 |
| D | ARG100 |
| D | GLU115 |
| D | HIS118 |
| D | HOH165 |
| D | HOH459 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 D 125 |
| Chain | Residue |
| A | GLY98 |
| A | ARG100 |
| A | HOH140 |
| A | HOH323 |
| A | HOH427 |
| A | HOH477 |
| A | HOH596 |
| D | LYS85 |
| D | GLY86 |
| D | ARG104 |
