3GKV
X-ray structure of an intermediate along the oxidation pathway of Trematomus bernacchii hemoglobin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005833 | cellular_component | hemoglobin complex |
| A | 0015671 | biological_process | oxygen transport |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0031720 | molecular_function | haptoglobin binding |
| A | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0043177 | molecular_function | organic acid binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0072562 | cellular_component | blood microparticle |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005344 | molecular_function | oxygen carrier activity |
| B | 0005833 | cellular_component | hemoglobin complex |
| B | 0015671 | biological_process | oxygen transport |
| B | 0019825 | molecular_function | oxygen binding |
| B | 0020037 | molecular_function | heme binding |
| B | 0031720 | molecular_function | haptoglobin binding |
| B | 0031721 | molecular_function | hemoglobin alpha binding |
| B | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0043177 | molecular_function | organic acid binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0072562 | cellular_component | blood microparticle |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM A 200 |
| Chain | Residue |
| A | TYR42 |
| A | VAL94 |
| A | ASN98 |
| A | LEU102 |
| A | ASN103 |
| A | LEU137 |
| A | CMO199 |
| A | HOH1103 |
| A | HOH1291 |
| A | PHE43 |
| A | HIS45 |
| A | TRP46 |
| A | HIS59 |
| A | LYS62 |
| A | GLN87 |
| A | HIS88 |
| A | LEU92 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM B 400 |
| Chain | Residue |
| B | HIS41 |
| B | PHE42 |
| B | HIS63 |
| B | LYS66 |
| B | HIS92 |
| B | LEU96 |
| B | VAL98 |
| B | ASN102 |
| B | PHE103 |
| B | LEU106 |
| B | LEU141 |
| B | CMO399 |
| B | HOH1265 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CMO A 199 |
| Chain | Residue |
| A | LEU29 |
| A | HIS59 |
| A | VAL63 |
| A | HEM200 |
| A | HOH1290 |
| A | HOH1291 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CMO B 399 |
| Chain | Residue |
| B | HIS63 |
| B | VAL67 |
| B | HEM400 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: distal binding residue => ECO:0007744|PDB:1S5X, ECO:0007744|PDB:1S5Y, ECO:0007744|PDB:2PEG, ECO:0007744|PDB:4IRO |
| Chain | Residue | Details |
| B | HIS63 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: proximal binding residue => ECO:0000269|PubMed:7623382, ECO:0007744|PDB:1HBH, ECO:0007744|PDB:1PBX, ECO:0007744|PDB:1S5X, ECO:0007744|PDB:1S5Y, ECO:0007744|PDB:2H8D, ECO:0007744|PDB:2H8F, ECO:0007744|PDB:2PEG, ECO:0007744|PDB:3GKV, ECO:0007744|PDB:3GQG, ECO:0007744|PDB:4G51, ECO:0007744|PDB:4IRO, ECO:0007744|PDB:4ODC |
| Chain | Residue | Details |
| B | HIS92 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylserine => ECO:0000269|PubMed:7623382 |
| Chain | Residue | Details |
| A | SER1 |
