3GK4

X-ray structure of bovine SBi523,Ca(2+)-S100B

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0005509	molecular_function	calcium ion binding
X	0005515	molecular_function	protein binding
X	0005576	cellular_component	extracellular region
X	0005615	cellular_component	extracellular space
X	0005634	cellular_component	nucleus
X	0005737	cellular_component	cytoplasm
X	0006417	biological_process	regulation of translation
X	0007155	biological_process	cell adhesion
X	0007409	biological_process	axonogenesis
X	0007611	biological_process	learning or memory
X	0008270	molecular_function	zinc ion binding
X	0008284	biological_process	positive regulation of cell population proliferation
X	0016310	biological_process	phosphorylation
X	0019210	molecular_function	kinase inhibitor activity
X	0042803	molecular_function	protein homodimerization activity
X	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
X	0044548	molecular_function	S100 protein binding
X	0045917	biological_process	positive regulation of complement activation
X	0046872	molecular_function	metal ion binding
X	0048143	biological_process	astrocyte activation
X	0048156	molecular_function	tau protein binding
X	0048306	molecular_function	calcium-dependent protein binding
X	0050786	molecular_function	RAGE receptor binding
X	0071638	biological_process	negative regulation of monocyte chemotactic protein-1 production
X	0097490	biological_process	sympathetic neuron projection extension
X	1990845	biological_process	adaptive thermogenesis

Functional Information from PDB Data

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DSDGDGECDfqEF

Chain	Residue	Details
X	ASP61-PHE73

site_id	PS00303
Number of Residues	22
Details	S100_CABP S-100/ICaBP type calcium binding protein signature. VMetLDsdgDgecDFqEFmaFV

Chain	Residue	Details
X	VAL56-VAL77

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P04271

site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU00448

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N-acetylserine => ECO:0000269\|PubMed:4026304

Chain	Residue	Details
X	SER1