Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0008234 | molecular_function | cysteine-type peptidase activity |
C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
C | 0006508 | biological_process | proteolysis |
C | 0008234 | molecular_function | cysteine-type peptidase activity |
D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
D | 0006508 | biological_process | proteolysis |
D | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE DZE A 1 |
Chain | Residue |
A | ARG64 |
B | ARG207 |
A | SER120 |
A | HIS121 |
A | GLY122 |
A | GLN161 |
A | CYS163 |
B | TYR204 |
B | SER205 |
B | TRP206 |
site_id | AC2 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE DZE C 2 |
Chain | Residue |
C | ARG64 |
C | SER120 |
C | HIS121 |
C | GLY122 |
C | GLN161 |
C | CYS163 |
D | TYR204 |
D | SER205 |
D | TRP206 |
D | ARG207 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL B 284 |
Chain | Residue |
B | TRP206 |
B | ASN208 |
B | TRP214 |
B | SER249 |
B | PHE250 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL D 284 |
Chain | Residue |
D | TRP206 |
D | ASN208 |
D | TRP214 |
D | SER249 |
D | PHE250 |
Functional Information from PROSITE/UniProt
site_id | PS01121 |
Number of Residues | 15 |
Details | CASPASE_HIS Caspase family histidine active site. HskrsSfvCvLLSHG |
Chain | Residue | Details |
A | HIS108-GLY122 | |
site_id | PS01122 |
Number of Residues | 12 |
Details | CASPASE_CYS Caspase family cysteine active site. KPKLFIIQACRG |
Chain | Residue | Details |
A | LYS154-GLY165 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS121 | |
A | CYS163 | |
C | HIS121 | |
C | CYS163 | |
Chain | Residue | Details |
A | CYS163 | |
C | CYS163 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1qx3 |
Chain | Residue | Details |
A | HIS121 | |
A | GLY122 | |
A | CYS163 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1qx3 |
Chain | Residue | Details |
C | HIS121 | |
C | GLY122 | |
C | CYS163 | |
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 815 |
Chain | Residue | Details |
A | THR62 | electrostatic stabiliser |
A | SER63 | electrostatic stabiliser |
A | HIS121 | electrostatic stabiliser, proton acceptor, proton donor |
A | GLY122 | electrostatic stabiliser |
A | CYS163 | electrostatic stabiliser |
site_id | MCSA2 |
Number of Residues | 5 |
Details | M-CSA 815 |
Chain | Residue | Details |
C | THR62 | electrostatic stabiliser |
C | SER63 | electrostatic stabiliser |
C | HIS121 | electrostatic stabiliser, proton acceptor, proton donor |
C | GLY122 | electrostatic stabiliser |
C | CYS163 | electrostatic stabiliser |