Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3GIT

Crystal structure of a truncated acetyl-CoA synthase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0006084	biological_process	acetyl-CoA metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0018492	molecular_function	carbon-monoxide dehydrogenase (acceptor) activity
B	0003824	molecular_function	catalytic activity
B	0006084	biological_process	acetyl-CoA metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0018492	molecular_function	carbon-monoxide dehydrogenase (acceptor) activity
C	0003824	molecular_function	catalytic activity
C	0006084	biological_process	acetyl-CoA metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0018492	molecular_function	carbon-monoxide dehydrogenase (acceptor) activity
D	0003824	molecular_function	catalytic activity
D	0006084	biological_process	acetyl-CoA metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0018492	molecular_function	carbon-monoxide dehydrogenase (acceptor) activity
E	0003824	molecular_function	catalytic activity
E	0006084	biological_process	acetyl-CoA metabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0018492	molecular_function	carbon-monoxide dehydrogenase (acceptor) activity
F	0003824	molecular_function	catalytic activity
F	0006084	biological_process	acetyl-CoA metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0018492	molecular_function	carbon-monoxide dehydrogenase (acceptor) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SF4 A 738

Chain	Residue
A	ARG405
A	CYS506
A	CYS509
A	CYS518
A	LEU527
A	CYS528
A	VAL531
A	ZN739

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 739

Chain	Residue
A	CYS595
A	CYS597
A	SF4738
A	H2S740
A	CYS509

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE H2S A 740

Chain	Residue
A	CYS595
A	GLY596
A	CYS597
A	ZN739

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 741

Chain	Residue
A	PRO377
A	GLU378
E	LYS335
E	LYS381

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 742

Chain	Residue
A	GLU554
A	GLY555
A	GLU556

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 743

Chain	Residue
A	ILE333
A	TRP418
A	SO4744
A	HOH759

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 744

Chain	Residue
A	ARG334
A	LYS335
A	ARG429
A	GOL743

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 745

Chain	Residue
A	ARG354
A	TYR477

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 746

Chain	Residue
A	LYS335
A	LYS381
F	PRO377
F	GLU378

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SF4 B 738

Chain	Residue
B	ARG405
B	CYS506
B	CYS509
B	CYS518
B	LEU527
B	CYS528
B	ZN739

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 739

Chain	Residue
B	CYS509
B	CYS595
B	CYS597
B	SF4738
B	H2S740

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE H2S B 740

Chain	Residue
B	CYS595
B	GLY596
B	CYS597
B	ZN739

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 742

Chain	Residue
B	GLU554
B	GLY555
B	GLU556

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 743

Chain	Residue
B	SER332
B	ILE333
B	TRP418
B	TRP427
B	HOH758
B	HOH759

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 744

Chain	Residue
B	ILE333
B	ARG334
B	LYS335
B	ARG429
B	HOH756

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 745

Chain	Residue
B	ARG354
B	TYR477

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 741

Chain	Residue
B	LYS335
B	LYS381
C	PRO377
C	GLU378

site_id	BC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SF4 C 738

Chain	Residue
C	ARG405
C	CYS506
C	CYS509
C	CYS518
C	GLY526
C	LEU527
C	CYS528
C	VAL531
C	ZN739

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 739

Chain	Residue
C	CYS509
C	CYS595
C	CYS597
C	SF4738
C	H2S740

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE H2S C 740

Chain	Residue
C	CYS509
C	CYS595
C	GLY596
C	CYS597
C	ZN739

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 742

Chain	Residue
C	GLU554
C	GLY555
C	GLU556

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL C 743

Chain	Residue
C	SER332
C	ILE333
C	TRP418

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 744

Chain	Residue
C	ARG334
C	LYS335
C	ARG429
C	HOH756

site_id	CC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 745

Chain	Residue
C	ARG354
C	TYR477

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 741

Chain	Residue
C	LYS335
C	LYS381
D	PRO377
D	GLU378

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 741

Chain	Residue
B	PRO377
B	GLU378
D	LYS335
D	LYS381

site_id	CC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SF4 D 738

Chain	Residue
D	ARG405
D	CYS506
D	CYS509
D	CYS518
D	GLY526
D	LEU527
D	CYS528
D	ZN739

site_id	DC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 739

Chain	Residue
D	CYS509
D	CYS595
D	CYS597
D	SF4738
D	H2S740

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE H2S D 740

Chain	Residue
D	CYS509
D	CYS595
D	GLY596
D	CYS597
D	ZN739

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 742

Chain	Residue
D	GLU554
D	GLY555
D	GLU556

site_id	DC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 743

Chain	Residue
D	SER332
D	ILE333
D	TRP418
D	TRP427
D	ARG429
D	HOH758

site_id	DC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 744

Chain	Residue
D	ILE333
D	ARG334
D	LYS335
D	ARG429
D	HOH756

site_id	DC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 745

Chain	Residue
D	ARG354
D	TYR477

site_id	DC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SF4 E 738

Chain	Residue
E	ARG405
E	CYS506
E	CYS509
E	CYS518
E	GLY526
E	LEU527
E	CYS528
E	VAL531
E	ZN739

site_id	DC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN E 739

Chain	Residue
E	CYS509
E	CYS595
E	CYS597
E	SF4738
E	H2S740

site_id	DC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE H2S E 740

Chain	Residue
E	CYS509
E	CYS595
E	GLY596
E	CYS597
E	ZN739

site_id	EC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 742

Chain	Residue
E	GLU554
E	GLY555
E	GLU556

site_id	EC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL E 743

Chain	Residue
E	SER332
E	ILE333
E	TRP418
E	TRP427
E	ARG429
E	SO4744
E	HOH759

site_id	EC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 744

Chain	Residue
E	ARG334
E	LYS335
E	ARG429
E	GOL743

site_id	EC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 745

Chain	Residue
E	ARG354
E	TYR477

site_id	EC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 741

Chain	Residue
E	PRO377
E	GLU378
F	LYS335
F	LYS381

site_id	EC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SF4 F 738

Chain	Residue
F	ARG405
F	CYS506
F	CYS509
F	CYS518
F	LEU527
F	CYS528
F	VAL531

site_id	EC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 739

Chain	Residue
F	CYS509
F	CYS595
F	CYS597
F	H2S740

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE H2S F 740

Chain	Residue
F	CYS595
F	GLY596
F	CYS597
F	ZN739

site_id	EC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 742

Chain	Residue
F	GLU554
F	GLY555
F	GLU556

site_id	FC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL F 743

Chain	Residue
F	SER332
F	ILE333
F	TRP418
F	TRP427
F	ARG429
F	SO4744
F	HOH759

site_id	FC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 744

Chain	Residue
F	ARG334
F	LYS335
F	ARG429
F	GOL743

site_id	FC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 745

Chain	Residue
F	ARG354
F	TYR477

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. LGILVDIYGRKmqadfeG

Chain	Residue	Details
A	LEU384-GLY401

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	42
Details	BINDING:

Chain	Residue	Details
A	CYS506
C	CYS595
C	GLY596
C	CYS597
D	CYS506
D	CYS509
D	CYS518
D	CYS528
D	CYS595
D	GLY596
D	CYS597
E	CYS506
E	CYS509
E	CYS518
E	CYS528
E	CYS595
E	GLY596
E	CYS597
F	CYS506
F	CYS509
F	CYS518
F	CYS528
F	CYS595
F	GLY596
F	CYS597
A	CYS509
A	CYS518
A	CYS528
A	CYS595
A	GLY596
A	CYS597
B	CYS506
B	CYS509
B	CYS518
B	CYS528
B	CYS595
B	GLY596
B	CYS597
C	CYS506
C	CYS509
C	CYS518
C	CYS528

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)