3GIT
Crystal structure of a truncated acetyl-CoA synthase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0043885 | molecular_function | anaerobic carbon-monoxide dehydrogenase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0006084 | biological_process | acetyl-CoA metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0043885 | molecular_function | anaerobic carbon-monoxide dehydrogenase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0006084 | biological_process | acetyl-CoA metabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0043885 | molecular_function | anaerobic carbon-monoxide dehydrogenase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0006084 | biological_process | acetyl-CoA metabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0043885 | molecular_function | anaerobic carbon-monoxide dehydrogenase activity |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0006084 | biological_process | acetyl-CoA metabolic process |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0043885 | molecular_function | anaerobic carbon-monoxide dehydrogenase activity |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0006084 | biological_process | acetyl-CoA metabolic process |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0043885 | molecular_function | anaerobic carbon-monoxide dehydrogenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 A 738 |
| Chain | Residue |
| A | ARG405 |
| A | CYS506 |
| A | CYS509 |
| A | CYS518 |
| A | LEU527 |
| A | CYS528 |
| A | VAL531 |
| A | ZN739 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 739 |
| Chain | Residue |
| A | CYS595 |
| A | CYS597 |
| A | SF4738 |
| A | H2S740 |
| A | CYS509 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE H2S A 740 |
| Chain | Residue |
| A | CYS595 |
| A | GLY596 |
| A | CYS597 |
| A | ZN739 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 741 |
| Chain | Residue |
| A | PRO377 |
| A | GLU378 |
| E | LYS335 |
| E | LYS381 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 742 |
| Chain | Residue |
| A | GLU554 |
| A | GLY555 |
| A | GLU556 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 743 |
| Chain | Residue |
| A | ILE333 |
| A | TRP418 |
| A | SO4744 |
| A | HOH759 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 744 |
| Chain | Residue |
| A | ARG334 |
| A | LYS335 |
| A | ARG429 |
| A | GOL743 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 745 |
| Chain | Residue |
| A | ARG354 |
| A | TYR477 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 746 |
| Chain | Residue |
| A | LYS335 |
| A | LYS381 |
| F | PRO377 |
| F | GLU378 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SF4 B 738 |
| Chain | Residue |
| B | ARG405 |
| B | CYS506 |
| B | CYS509 |
| B | CYS518 |
| B | LEU527 |
| B | CYS528 |
| B | ZN739 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 739 |
| Chain | Residue |
| B | CYS509 |
| B | CYS595 |
| B | CYS597 |
| B | SF4738 |
| B | H2S740 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE H2S B 740 |
| Chain | Residue |
| B | CYS595 |
| B | GLY596 |
| B | CYS597 |
| B | ZN739 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 742 |
| Chain | Residue |
| B | GLU554 |
| B | GLY555 |
| B | GLU556 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 743 |
| Chain | Residue |
| B | SER332 |
| B | ILE333 |
| B | TRP418 |
| B | TRP427 |
| B | HOH758 |
| B | HOH759 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 744 |
| Chain | Residue |
| B | ILE333 |
| B | ARG334 |
| B | LYS335 |
| B | ARG429 |
| B | HOH756 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 745 |
| Chain | Residue |
| B | ARG354 |
| B | TYR477 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 741 |
| Chain | Residue |
| B | LYS335 |
| B | LYS381 |
| C | PRO377 |
| C | GLU378 |
| site_id | BC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SF4 C 738 |
| Chain | Residue |
| C | ARG405 |
| C | CYS506 |
| C | CYS509 |
| C | CYS518 |
| C | GLY526 |
| C | LEU527 |
| C | CYS528 |
| C | VAL531 |
| C | ZN739 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 739 |
| Chain | Residue |
| C | CYS509 |
| C | CYS595 |
| C | CYS597 |
| C | SF4738 |
| C | H2S740 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE H2S C 740 |
| Chain | Residue |
| C | CYS509 |
| C | CYS595 |
| C | GLY596 |
| C | CYS597 |
| C | ZN739 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 742 |
| Chain | Residue |
| C | GLU554 |
| C | GLY555 |
| C | GLU556 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 743 |
| Chain | Residue |
| C | SER332 |
| C | ILE333 |
| C | TRP418 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 744 |
| Chain | Residue |
| C | ARG334 |
| C | LYS335 |
| C | ARG429 |
| C | HOH756 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 745 |
| Chain | Residue |
| C | ARG354 |
| C | TYR477 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 741 |
| Chain | Residue |
| C | LYS335 |
| C | LYS381 |
| D | PRO377 |
| D | GLU378 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 741 |
| Chain | Residue |
| B | PRO377 |
| B | GLU378 |
| D | LYS335 |
| D | LYS381 |
| site_id | CC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 D 738 |
| Chain | Residue |
| D | ARG405 |
| D | CYS506 |
| D | CYS509 |
| D | CYS518 |
| D | GLY526 |
| D | LEU527 |
| D | CYS528 |
| D | ZN739 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 739 |
| Chain | Residue |
| D | CYS509 |
| D | CYS595 |
| D | CYS597 |
| D | SF4738 |
| D | H2S740 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE H2S D 740 |
| Chain | Residue |
| D | CYS509 |
| D | CYS595 |
| D | GLY596 |
| D | CYS597 |
| D | ZN739 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 742 |
| Chain | Residue |
| D | GLU554 |
| D | GLY555 |
| D | GLU556 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 743 |
| Chain | Residue |
| D | SER332 |
| D | ILE333 |
| D | TRP418 |
| D | TRP427 |
| D | ARG429 |
| D | HOH758 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 744 |
| Chain | Residue |
| D | ILE333 |
| D | ARG334 |
| D | LYS335 |
| D | ARG429 |
| D | HOH756 |
| site_id | DC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 745 |
| Chain | Residue |
| D | ARG354 |
| D | TYR477 |
| site_id | DC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SF4 E 738 |
| Chain | Residue |
| E | ARG405 |
| E | CYS506 |
| E | CYS509 |
| E | CYS518 |
| E | GLY526 |
| E | LEU527 |
| E | CYS528 |
| E | VAL531 |
| E | ZN739 |
| site_id | DC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN E 739 |
| Chain | Residue |
| E | CYS509 |
| E | CYS595 |
| E | CYS597 |
| E | SF4738 |
| E | H2S740 |
| site_id | DC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE H2S E 740 |
| Chain | Residue |
| E | CYS509 |
| E | CYS595 |
| E | GLY596 |
| E | CYS597 |
| E | ZN739 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 742 |
| Chain | Residue |
| E | GLU554 |
| E | GLY555 |
| E | GLU556 |
| site_id | EC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL E 743 |
| Chain | Residue |
| E | SER332 |
| E | ILE333 |
| E | TRP418 |
| E | TRP427 |
| E | ARG429 |
| E | SO4744 |
| E | HOH759 |
| site_id | EC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 E 744 |
| Chain | Residue |
| E | ARG334 |
| E | LYS335 |
| E | ARG429 |
| E | GOL743 |
| site_id | EC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 E 745 |
| Chain | Residue |
| E | ARG354 |
| E | TYR477 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 F 741 |
| Chain | Residue |
| E | PRO377 |
| E | GLU378 |
| F | LYS335 |
| F | LYS381 |
| site_id | EC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SF4 F 738 |
| Chain | Residue |
| F | ARG405 |
| F | CYS506 |
| F | CYS509 |
| F | CYS518 |
| F | LEU527 |
| F | CYS528 |
| F | VAL531 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN F 739 |
| Chain | Residue |
| F | CYS509 |
| F | CYS595 |
| F | CYS597 |
| F | H2S740 |
| site_id | EC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE H2S F 740 |
| Chain | Residue |
| F | CYS595 |
| F | GLY596 |
| F | CYS597 |
| F | ZN739 |
| site_id | EC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 F 742 |
| Chain | Residue |
| F | GLU554 |
| F | GLY555 |
| F | GLU556 |
| site_id | FC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL F 743 |
| Chain | Residue |
| F | SER332 |
| F | ILE333 |
| F | TRP418 |
| F | TRP427 |
| F | ARG429 |
| F | SO4744 |
| F | HOH759 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 F 744 |
| Chain | Residue |
| F | ARG334 |
| F | LYS335 |
| F | ARG429 |
| F | GOL743 |
| site_id | FC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 F 745 |
| Chain | Residue |
| F | ARG354 |
| F | TYR477 |
Functional Information from PROSITE/UniProt
| site_id | PS00216 |
| Number of Residues | 18 |
| Details | SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. LGILVDIYGRKmqadfeG |
| Chain | Residue | Details |
| A | LEU384-GLY401 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | CYS506 | |
| B | CYS518 | |
| B | CYS528 | |
| B | CYS595 | |
| B | GLY596 | |
| B | CYS597 | |
| C | CYS506 | |
| C | CYS509 | |
| C | CYS518 | |
| C | CYS528 | |
| C | CYS595 | |
| A | CYS509 | |
| C | GLY596 | |
| C | CYS597 | |
| D | CYS506 | |
| D | CYS509 | |
| D | CYS518 | |
| D | CYS528 | |
| D | CYS595 | |
| D | GLY596 | |
| D | CYS597 | |
| E | CYS506 | |
| A | CYS518 | |
| E | CYS509 | |
| E | CYS518 | |
| E | CYS528 | |
| E | CYS595 | |
| E | GLY596 | |
| E | CYS597 | |
| F | CYS506 | |
| F | CYS509 | |
| F | CYS518 | |
| F | CYS528 | |
| A | CYS528 | |
| F | CYS595 | |
| F | GLY596 | |
| F | CYS597 | |
| A | CYS595 | |
| A | GLY596 | |
| A | CYS597 | |
| B | CYS506 | |
| B | CYS509 |
