3GHZ
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0008685 | molecular_function | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity |
| A | 0016114 | biological_process | terpenoid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019288 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0008685 | molecular_function | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity |
| B | 0016114 | biological_process | terpenoid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019288 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0008299 | biological_process | isoprenoid biosynthetic process |
| C | 0008685 | molecular_function | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity |
| C | 0016114 | biological_process | terpenoid biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019288 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 303 |
| Chain | Residue |
| A | SER35 |
| A | ILE57 |
| A | GLY58 |
| A | PHE61 |
| A | ASP63 |
| A | HOH191 |
| A | HOH209 |
| A | HOH210 |
| A | HOH250 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 304 |
| Chain | Residue |
| A | ASP8 |
| A | HOH165 |
| A | HOH198 |
| A | HOH205 |
| C | HOH214 |
| C | HOH215 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 307 |
| Chain | Residue |
| A | GLU149 |
| B | GLU149 |
| C | GLU149 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POP B 301 |
| Chain | Residue |
| A | GLY138 |
| A | PHE139 |
| A | ARG142 |
| B | GLY138 |
| B | PHE139 |
| B | ARG142 |
| B | HOH220 |
| C | GLY138 |
| C | PHE139 |
| C | ARG142 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 306 |
| Chain | Residue |
| A | HOH167 |
| A | HOH176 |
| A | HOH181 |
| B | ASP8 |
| B | HOH180 |
| B | HOH182 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL C 302 |
| Chain | Residue |
| C | SER35 |
| C | ILE57 |
| C | GLY58 |
| C | PHE61 |
| C | ASP63 |
| C | HOH190 |
| C | HOH192 |
| C | HOH207 |
| C | HOH208 |
| C | HOH273 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 305 |
| Chain | Residue |
| B | HOH271 |
| B | HOH272 |
| C | ASP8 |
| C | HOH160 |
| C | HOH218 |
| C | HOH273 |
Functional Information from PROSITE/UniProt
| site_id | PS01350 |
| Number of Residues | 16 |
| Details | ISPF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. SDGDVAlHAltDAllG |
| Chain | Residue | Details |
| A | SER35-GLY50 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 69 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00107","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_00107","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
