3GFD
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN and mono-iodotyrosine (MIT)
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FMN A 301 |
| Chain | Residue |
| A | HOH15 |
| A | THR235 |
| A | ARG275 |
| A | IYR302 |
| A | HOH372 |
| A | HOH395 |
| B | PRO123 |
| B | SER124 |
| B | GLY125 |
| B | HOH553 |
| A | HOH17 |
| A | ARG96 |
| A | ARG97 |
| A | SER98 |
| A | ARG100 |
| A | THR174 |
| A | VAL232 |
| A | THR233 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE IYR A 302 |
| Chain | Residue |
| A | GLU153 |
| A | TYR157 |
| A | LEU169 |
| A | THR174 |
| A | ASN175 |
| A | LYS178 |
| A | THR235 |
| A | FMN301 |
| A | HOH356 |
| A | HOH400 |
| B | GLY125 |
| B | ALA126 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1 |
| Chain | Residue |
| A | TYR207 |
| A | TYR208 |
| A | HOH331 |
| A | HOH411 |
| A | HOH415 |
| A | HOH462 |
| B | TRP165 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 3 |
| Chain | Residue |
| A | ARG76 |
| A | TYR77 |
| A | GLU81 |
| A | TYR157 |
| A | MET158 |
| A | VAL166 |
| A | LYS170 |
| site_id | AC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE FMN B 301 |
| Chain | Residue |
| A | PRO123 |
| A | SER124 |
| A | GLY125 |
| A | TYR208 |
| A | ILE211 |
| A | ILE215 |
| A | HOH416 |
| B | HOH13 |
| B | ARG96 |
| B | ARG97 |
| B | SER98 |
| B | ARG100 |
| B | LEU172 |
| B | VAL232 |
| B | THR233 |
| B | THR234 |
| B | THR235 |
| B | LEU273 |
| B | ARG275 |
| B | IYR302 |
| B | HOH308 |
| B | HOH333 |
| B | HOH550 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE IYR B 302 |
| Chain | Residue |
| A | GLY125 |
| A | ALA126 |
| A | TYR207 |
| B | GLU153 |
| B | TYR157 |
| B | MET161 |
| B | LEU169 |
| B | LEU172 |
| B | ASN175 |
| B | LYS178 |
| B | THR235 |
| B | FMN301 |
| B | HOH314 |
| B | HOH320 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 2 |
| Chain | Residue |
| A | LEU237 |
| B | TYR207 |
| B | TYR208 |
| B | HOH532 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19436071","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22238141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GB5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GH8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TNZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TO0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3GFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TNZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19436071","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22238141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3GFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TNZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
