3GE3

Crystal Structure of the reduced Toluene 4-Monooxygenase HD T201A mutant complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0006725	biological_process	obsolete cellular aromatic compound metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0018638	molecular_function	toluene 4-monooxygenase activity
A	0019439	biological_process	obsolete aromatic compound catabolic process
A	0042203	biological_process	toluene catabolic process
A	0046872	molecular_function	metal ion binding
B	0004497	molecular_function	monooxygenase activity
B	0006725	biological_process	obsolete cellular aromatic compound metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
B	0018638	molecular_function	toluene 4-monooxygenase activity
B	0019439	biological_process	obsolete aromatic compound catabolic process
B	0042203	biological_process	toluene catabolic process
C	0004497	molecular_function	monooxygenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0018638	molecular_function	toluene 4-monooxygenase activity
C	0019439	biological_process	obsolete aromatic compound catabolic process
C	0042203	biological_process	toluene catabolic process
E	0004497	molecular_function	monooxygenase activity
E	0006725	biological_process	obsolete cellular aromatic compound metabolic process
E	0019439	biological_process	obsolete aromatic compound catabolic process
E	0042203	biological_process	toluene catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 501

Chain	Residue
A	GLU134
A	GLU197
A	GLU231
A	HIS234
A	FE502
A	HOH900
A	ACT1428

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 502

Chain	Residue
A	HIS137
A	FE501
A	HOH689
A	HOH900
A	ACT1428
A	GLU104
A	GLU134

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site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ACT A 1428

Chain	Residue
A	GLU104
A	GLU134
A	ILE180
A	PHE196
A	GLU197
A	GLU231
A	FE501
A	FE502
A	HOH689
A	HOH900

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 503

Chain	Residue
A	ARG339
A	LYS481
A	ASP482

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:19033467, ECO:0000269|PubMed:19290655, ECO:0000269|PubMed:19705873, ECO:0000269|PubMed:22264099, ECO:0000269|PubMed:25248368, ECO:0000269|PubMed:28346937, ECO:0007744|PDB:3Q14, ECO:0007744|PDB:3Q2A, ECO:0007744|PDB:3Q3M, ECO:0007744|PDB:3Q3N, ECO:0007744|PDB:3Q3O, ECO:0007744|PDB:3RI7, ECO:0007744|PDB:3RMK, ECO:0007744|PDB:4P1B, ECO:0007744|PDB:4P1C, ECO:0007744|PDB:5TDS, ECO:0007744|PDB:5TDT, ECO:0007744|PDB:5TDU, ECO:0007744|PDB:5TDV

Chain	Residue	Details
A	GLU104
A	GLU134
A	HIS137
A	GLU197
A	GLU231
A	HIS234

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