Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003909 | molecular_function | DNA ligase activity |
| A | 0003910 | molecular_function | DNA ligase (ATP) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006260 | biological_process | DNA replication |
| A | 0006273 | biological_process | lagging strand elongation |
| A | 0006281 | biological_process | DNA repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051301 | biological_process | cell division |
| A | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 556 |
| Chain | Residue |
| A | ARG269 |
| A | ARG411 |
| A | LYS417 |
| A | PO4557 |
| A | HOH586 |
| A | HOH587 |
| A | HOH692 |
| A | HOH890 |
| A | HOH893 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 A 557 |
| Chain | Residue |
| A | LYS249 |
| A | GLU395 |
| A | LYS417 |
| A | LYS419 |
| A | GLU423 |
| A | PO4556 |
| A | PO4558 |
| A | HOH870 |
| A | HOH971 |
| A | HOH1012 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 558 |
| Chain | Residue |
| A | ARG528 |
| A | LYS531 |
| A | PO4557 |
| A | HOH730 |
| A | HOH890 |
| A | HOH904 |
| A | HOH990 |
| A | HOH1012 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 559 |
| Chain | Residue |
| A | GLN311 |
| A | ARG526 |
| A | HOH748 |
| A | HOH866 |
Functional Information from PROSITE/UniProt
| site_id | PS00333 |
| Number of Residues | 25 |
| Details | DNA_LIGASE_A2 ATP-dependent DNA ligase signature 2. EGVMIKlpssp...YIpgkrg.Knwl..KVK |
| Chain | Residue | Details |
| A | GLU395-LYS419 | |
| site_id | PS00697 |
| Number of Residues | 9 |
| Details | DNA_LIGASE_A1 ATP-dependent DNA ligase AMP-binding site. EWKFDGSRV |
| Chain | Residue | Details |
| A | GLU247-VAL255 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"N6-AMP-lysine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_00407","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00407","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a0i |
| Chain | Residue | Details |
| A | LYS249 | |
