3GBU

Crystal structure of an uncharacterized sugar kinase PH1459 from Pyrococcus horikoshii in complex with ATP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0006000	biological_process	fructose metabolic process
A	0008865	molecular_function	fructokinase activity
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0046835	biological_process	carbohydrate phosphorylation
B	0005524	molecular_function	ATP binding
B	0006000	biological_process	fructose metabolic process
B	0008865	molecular_function	fructokinase activity
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0046835	biological_process	carbohydrate phosphorylation
C	0005524	molecular_function	ATP binding
C	0006000	biological_process	fructose metabolic process
C	0008865	molecular_function	fructokinase activity
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0046835	biological_process	carbohydrate phosphorylation
D	0005524	molecular_function	ATP binding
D	0006000	biological_process	fructose metabolic process
D	0008865	molecular_function	fructokinase activity
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0046835	biological_process	carbohydrate phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ATP A 900

Chain	Residue
A	ARG164
A	GLY246
A	ALA276
A	HOH333
A	HOH353
A	HOH354
A	HOH355
A	HOH387
A	HOH460
A	HOH476
A	HOH510
A	LYS190
A	THR215
A	GLY217
A	GLY220
A	PHE221
A	VAL237
A	PRO239
A	ALA245

---

site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ATP B 900

Chain	Residue
B	ASN162
B	LYS190
B	THR215
B	GLY217
B	GLY220
B	SER234
B	TYR235
B	VAL237
B	ALA245
B	GLY246
B	ALA276
B	HOH340
B	HOH344
B	HOH351
B	HOH353
B	HOH410

---

site_id	AC3
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ATP C 900

Chain	Residue
C	LYS190
C	THR215
C	PHE221
C	TYR235
C	VAL237
C	ALA245
C	GLY246
C	ASN273
C	ALA276
C	ALA277
C	HOH328
C	HOH338
C	HOH339
C	HOH361
C	HOH362
C	HOH366
C	HOH376
C	HOH381
C	HOH449

---

site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ATP D 900

Chain	Residue
D	LYS190
D	THR215
D	GLY217
D	PRO218
D	GLY220
D	PHE221
D	SER234
D	TYR235
D	VAL237
D	PRO239
D	ALA245
D	GLY246
D	ALA276
D	HOH329
D	HOH333
D	HOH340
D	HOH349
D	HOH403
D	HOH629

---

Functional Information from PROSITE/UniProt

site_id	PS00583
Number of Residues	25
Details	PFKB_KINASES_1 pfkB family of carbohydrate kinases signature 1. GGaPaNVAvgVsRLGvkssliskvG

Chain	Residue	Details
A	GLY33-GLY57

---

site_id	PS00584
Number of Residues	14
Details	PFKB_KINASES_2 pfkB family of carbohydrate kinases signature 2. DTtGAGDafmAALL

Chain	Residue	Details
A	ASP241-LEU254

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0007744|PDB:3GBU

Chain	Residue	Details
A	LYS190
D	LYS190
D	THR215
D	GLY220
A	THR215
A	GLY220
B	LYS190
B	THR215
B	GLY220
C	LYS190
C	THR215
C	GLY220

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1rk2

Chain	Residue	Details
A	ALA245
A	GLY246
A	ASP247
A	GLY244

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1rk2

Chain	Residue	Details
B	ALA245
B	GLY246
B	ASP247
B	GLY244

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1rk2

Chain	Residue	Details
C	ALA245
C	GLY246
C	ASP247
C	GLY244

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1rk2

Chain	Residue	Details
D	ALA245
D	GLY246
D	ASP247
D	GLY244

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